Clinical Efficacy of Laparoscopic Operation Combined with Neiyi Xiaozheng Decoction on Endometriosis Associated with Infertility

Objective This study was purposed to investigate the clinical efficacy of laparoscopic surgery combined with Neiyi Xiaozheng decoction on endometriosis(EM)associated with infertility.Methods Sixty patients with EM infertility in our hospital from June 2011 to December 2011 were selected and randomly divided into two groups.The control group received laparoscopic operation(n=30) and the observation group was treated with Neiyi Xiaozheng decoction on the basis of laparoscopic operation(n=28).The clinical efficacy,pregnancy rate,serum cancer antigen 125(CA125),adverse reactions and relapse rate were observed and compared between the two groups.Results The pregnancy rate of observation group was 67.86% after one year which was significantly higher than that of control group(P 0.05).The serum CA125 level in the observation group was 12.71±10.08(U/ml) and it was significantly lower than that in the control group(P 0.05).But there was no obvious difference in adverse reaction rate between two groups.Conclusion Laparoscopic surgery combined with Neiyi Xiaozheng decoction could improve the clinical pregnancy rate and the blood stasis state.This method is effective for treating EM infertility without obvious adverse reaction.