Effect of Hydrogenated Palm Oil and Milk Ghee on Plasma Lipids and White Adipose Tissues in Rats

The type of dietary fat may affect blood lipids or/and obesity, leading to various diseases. Hyperlipidemia is an increase in total cholesterol (TC), low-density lipoproteins (LDL-C), triglycerides (TG), or all of them. Objective: This study aimed to investigate the effect of milk ghee (MG) and hydrogenated palm oil (HPO) on plasma lipids and white adipose tissue as an obesity indicator in rats. Method: Twelve male albino rats were divided into two groups, each group fed on a diet containing different fats for eight weeks. Plasma TC, high-density lipoproteins (HDL-C), VLDL-C&LDL-C and TG were analyzed. White adi-pose tissues were investigated. Results: Results showed that rats fed HPO had signifi-cantly higher levels of HDL-C than rats fed MG (56.33 and 51.66 mg/dl) respectively. The MG group had significantly high levels of TC, LDL-C, and TG (86.4, 34.73, and 56.20 mg/dl), and the HPO group recorded (81.14, 24.80, and 47.13 mg/dl). Rats fed HPO have a significant decrease in white adipose tissue weight than the MG group, and a small size of adipose cells. Conclusion: The consumption of hydrogenated palm oil could have a bene-ficial impact on improving plasma lipids and obesity instead of milk ghee.