Research progress of the pathogenesis of endometriosis

中华妇幼临床医学杂志(电子版) ›› 2015, Vol. 11 ›› Issue (01) : 121 -123. doi: 10.3877/cma.j.issn.1673-5250.2015.01.029 所属专题： 文献； 综述 子宫内膜异位症发病机制的研究进展 - 1. 524000 广东省湛江市，广东医学院 2. 516000 广东省惠州市中心人民医院妇科 - 1. Guangdong Medical College, Zhanjiang 524000, Guangdong Province, China 2. Department of Gynecology, Huizhou Municipal Central Hospital, Huizhou 516000, Guangdong Province, China 子宫内膜异位症(EM)是指具有生长功能的子宫内膜组织出现在子宫腔被覆内膜及子宫体肌层以外的其他部位，是育龄期妇女的常见疾病。目前EM的发病机制尚未明确，可能与子宫内膜干细胞、甾体类激素及其受体、新生血管生成、炎症与免疫等因素有关。笔者拟就EM发病机制的研究进展进行综述如下。 Endometriosis(EM) is defined as the presence of endometrial glands, stroma outside of the endometrial lining and uterine musculature. EM is a common gynecologic disorder among women of reproductive age. Its pathogenesis remains not clear. Current studies suggest that endometrial stem cell, steroid hormones and its veceptors, genetic factors, neovascularization, inflammation and immune may all play important roles in the pathogenesis of EM. 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