Differentiating coronavirus disease 2019 (COVID-19) from influenza and dengue

Differentiating coronavirus disease 2019 (COVID-19) from influenza and dengue | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Differentiating coronavirus disease 2019 (COVID-19) from influenza and dengue Tun-Linn Thein, Li Wei Ang, Barnaby Edward Young, Mark IC Chen, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-36343/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 05 Oct, 2021 Read the published version in Scientific Reports → Version 1 posted You are reading this latest preprint version Abstract Background: The novel coronavirus disease 2019 (COVID-19) presents with non-specific clinical features. This may result in misdiagnosis or delayed diagnosis, and lead to further transmission in the community. We aimed to derive early predictors to differentiate COVID-19 from influenza and dengue. Methods: The study comprised 126 patients with COVID-19, 171 with influenza and 180 with dengue, who presented within 5 days of symptom onset. All cases were confirmed by reverse transcriptase polymerase chain reaction tests. We used logistic regression models to identify clinical characteristics and laboratory markers in classifying COVID-19 versus influenza, and COVID-19 versus dengue. The performance of the models were evaluated using receiver operating characteristic curves (ROC). Results: Shortness of breath was the strongest predictor in the models for differentiating between COVID-19 and influenza, followed by diarrhoea. Higher lymphocyte count was predictive of COVID-19 versus influenza and versus dengue. In the model for differentiating between COVID-19 and dengue, patients with cough and higher platelet count were at increased odds of COVID-19, while headache, joint pain, skin rash and vomiting/nausea were indicative of dengue. The area under the ROC was 0.92 for flu model and 0.99 for dengue model. Conclusion: Models based on clinical features and simple laboratory markers for differentiating COVID-19 from influenza and dengue, which possess good predictive performance, can serve as a useful tool for primary care physicians to determine if further investigations or referrals would be required. Infectious Diseases COVID-19 influenza dengue Singapore predictive models Figures Figure 1 Figure 2 Introduction A cluster of cases of pneumonia with unknown cause was detected in Wuhan in December 2019 [1] . Caused by a novel human coronavirus now named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it has since spread rapidly on a global scale. On 11 March 2020, the World Health Organization (WHO) declared the novel coronavirus disease (COVID-19) as a pandemic, and expressed deep concern about the alarming levels of spread and severity [2] . Confirmation of acute SARS-CoV-2 infection requires detection of the virus in respiratory samples by reverse transcriptase polymerase chain reaction (RT-PCR) test. Clinical presentation of COVID-19 patients ranges from asymptomatic to mild non-specific acute symptoms such as fever, dry cough and fatigue [3] . Close to 20% of COVID-19 cases may be severe [4] . Influenza is prevalent globally and remains an important cause of morbidity and mortality from respiratory viral infections [5] while dengue is prevalent in tropical countries with geographic expansion [6] . Dengue is also known as not only the leading cause of fever in returning travelers in non-endemic countries, but also the main source for triggering autochthonous transmissions [7] , [8] . Since clinical presentations of these common viral infections are non-specific, it is difficult for primary care physicians to differentiate COVID-19 from influenza and dengue. This may result in misdiagnosis or delayed diagnosis, and lead to further transmission in the community. As the COVID-19 pandemic progresses, doctors in both dengue endemic [9] , [10] , [11] and non-endemic countries where influenza may be the most relevant differential diagnosis for COVID-19 5 , [12] , should maintain a high level of suspicion and be provided with effective tools to differentiate these three infections. Singapore is a tropical city state with several endemic viral infections. Influenza circulates year round with bimodal peaks typically observed in April-July and November-January [13] . Dengue epidemics of increasing magnitude have occurred in a five- to six-year cycle affecting more adults than children [14] . As of 15 Jun 2020, a total of 40,818 cases of the COVID-19 including 26 deaths have been reported in Singapore [15] . It is of concern that two local cases of COVID-19 with false positive dengue serology were reported in Singapore without travel or contact history [16] . In this study, we compared clinical presentations and laboratory parameters of patients with COVID-19, influenza and dengue. We constructed predictive models using logistic regression with the aim to assist doctors in differentiating COVID-19 from influenza and dengue based on clinical features and simple laboratory investigations. Methods Cohort description Our study population comprised laboratory confirmed COVID-19 from an ongoing prospective cohort, and influenza and dengue patients from previous studies. Briefly, prospective recruitment of COVID-19 patients took place from January to April 2020 at the National Centre for Infectious Diseases (NCID), Singapore 3 . Influenza patients were selected from a retrospective study of those who presented at Tan Tock Seng Hospital (TTSH), the primary centre for screening, treatment and isolation of H1N1(pdm09) cases from April to June 2009 in Singapore [17] . Dengue patients were selected from a prospective cohort study where adult patients presented with acute undifferentiated febrile illness to TTSH from January 2010 to September 2012 [18] . At first presentation to the hospital, demographic data, symptoms and signs were collected. Full blood count, renal and liver function tests were performed. SARS-CoV-2, influenza and dengue viruses were detected in respiratory samples or venous blood by RT-PCR tests 3 , 17 , 18 . Data of 215 patients with COVID-19, 200 with H1N1(pdm09) or seasonal influenza, and 300 with dengue (predominantly dengue virus serotype 2) were extracted. As our objective was to derive early predictors to differentiate COVID-19 from influenza and dengue, we analysed only symptomatic patients who presented to hospital within 5 days after symptom onset. Ethics Data for COVID-19 cohort was collected with waiver of informed consent granted by Ministry of Health, Singapore, under the Infectious Diseases Act as part of COVID-19 outbreak investigation. Research samples and data for the prospective COVID-19 and dengue cohort studies were collected with written informed consent approved by the Domain Specific Review Board (DSRB) of the National Healthcare Group, Singapore (DSRB/ E/12/917 and DSRB/E/09/432). Waiver of informed consent was approved for the retrospective study for influenza patients by the same review board (DSRB/E/09/344). Statistical analysis Fisher’s exact test was used to compare categorical variables and Mann-Whitney U test to compare continuous variables between any two groups. All statistical tests were two-sided, and statistical significance was taken as P < 0.05. We used multivariable logistic regression models as predictive tools to differentiate between COVID-19 and influenza, and COVID-19 and dengue. We followed the transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD) 2015 guideline [19] . Two multivariable models were fitted for differentiating COVID-19 versus influenza (flu models 1 and 2) and COVID-19 versus dengue (dengue models 1 and 2): flu model 1 and dengue model 1 contained demographics and symptoms, whereas flu model 2 and dengue model 2 included laboratory parameters in addition to demographics and symptoms. For the analysis on COVID-19 versus influenza, the proportion of missing data for laboratory parameters ranged from 3.4% (10 out of total 297 observations) for WBC count, haemoglobin, platelet, neutrophil count and lymphocyte count, to 28.3% (84 observations) for albumin, alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The variables for flu models 1 and 2 were selected through stepwise use of Akaike’s information criterion. Multicollinearity was then checked using variance inflation factor (VIF) for the final predictor variables included in these 2 multivariable models, which ranged from 1.01 to 1.25. For the analysis on COVID-19 versus dengue, the proportion of missing data for laboratory parameters ranged from 3.3% (10 out of total 306 observations) for WBC count, haemoglobin, haematocrit, platelet, neutrophil count and lymphocyte count, to 9.2% (28 observations) for AST. As the data for differentiating COVID-19 versus dengue exhibited separation, finite estimates of adjusted odds ratios (aOR) and Wald confidence intervals (CI) could not be obtained. Hence, we applied Firth’s modified score procedure to estimate OR and derived CI using the profile-penalized likelihood function [20] . The variables in dengue models 1 and 2 were selected by backward stepwise approach using penalized likelihood ratio tests. The VIF for the final predictor variables ranged from 1.01 to 1.23 for dengue model 1, and it ranged from 1.31 to 3.67 in dengue model 2 when laboratory parameters were included. We assessed the predictive performance of the multivariable logistic regression models using receiver operating characteristic (ROC) curves and the corresponding area under the ROC (AUC). Results This study comprised 126 patients with COVID-19, 171 with influenza and 180 with dengue, who presented within 5 days after symptom onset. The demographic characteristics of the patients are shown in Table 1. The age of COVID-19 patients was older compared with influenza and dengue patients. A lower proportion of COVID-19 patients were male compared with dengue patients. The proportion of COVID-19 patients having comorbidities was higher compared with dengue patients but not with influenza patients. The clinical features of patients with COVID-19, influenza and dengue at presentation are shown in Table 2. Shortness of breath and diarrhoea were more common in COVID-19 patients than in influenza patients, while fever, cough, running nose and sore throat were less common. Cough, shortness of breath, running nose and sore throat were more common in COVID-19 patients than in dengue patients. A lower proportion of COVID-19 patients had fever, diarrhoea, muscle aches, fatigue/malaise, abdominal pain, bleeding, conjunctivitis, headache, joint pain, skin rash and vomiting/nausea compared with dengue patients. We also provided an infographic of percentage of COVID-19, influenza and dengue patients with each symptom at presentation. It can be seen that COVID-19 and influenza patients have similar symptoms, while dengue patients present with symptoms that are significantly different from the other two groups (See Supplementary Table S1). The vital signs and laboratory parameters of patients with COVID-19, influenza and dengue are shown in Table 3. COVID-19 patients had lower white blood cell (WBC) count, neutrophil count and creatinine compared with influenza patients whereas their lymphocyte count and alanine aminotransferase (ALT) were higher. WBC, platelet, neutrophil and lymphocyte counts and albumin were higher in COVID-19 patients than dengue patients. The haemoglobin, haematocrit, aspartate aminotransferase (AST) and creatinine were lower in COVID-19 patients than dengue patients. The multivariable logistic regressions differentiating COVID-19 from influenza are shown in Table 4. In flu model 1 containing demographics and symptoms, older age (aOR 1.09; 95% CI: 1.07–1.12), shortness of breath (aOR 18.29; 95% CI: 2.28–411.81) and diarrhoea (aOR 13.70; 95% CI: 2.33–128.89) increased the odds that the patient had COVID-19, while fever, cough, running nose and vomiting/nauseas were indicative of influenza. In flu model 2 containing demographics, symptoms and laboratory parameters, older age (aOR 1.10; 95% CI: 1.07–1.13), shortness of breath (aOR 50.66; 95% CI: 3.09–1391.20), diarrhoea ((aOR 8.59; 95% CI: 1.67–67.62) and higher lymphocyte count (aOR 1.93; 95% CI: 1.09–3.46) were predictive of COVID-19, while cough, running nose and lower neutrophil count were indicative of influenza. Table 5 shows the multivariable logistic regression analysis differentiating COVID-19 versus dengue. In dengue model 1 containing demographics and symptoms, older age (aOR 1.06; 95% CI: 1.01–1.12) increased the odds that the patient had COVID-19, while fever, headache, joint pain, skin rash, vomiting/nauseas and bleeding were indicative of dengue. In dengue model 2 containing demographics, symptoms and laboratory parameters, patients who had cough (aOR 51.48; 95% CI: 4.47–4,662.18), higher platelet count (aOR 1.04; 95% CI: 1.01–1.09) and higher lymphocyte count (aOR 213.28; 95% CI: 9.65–98867.53) were at increased odds of COVID-19, while cough, headache, joint pain, skin rash and vomiting/nauseas were indicative of dengue. The AUC of flu model 1 containing demographics and symptoms was 0.893 (95% CI 0.856–0.931), and the AUC of flu model 2 which included laboratory parameters in differentiating COVID-19 versus influenza was 0.920 (95% CI 0.888–0.953) (Figure 1). The AUC of dengue model 1 without laboratory parameters and of dengue model 2 which included laboratory parameters for differentiating COVID-19 versus dengue were 0.995 (95% CI 0.992–1.000) and 0.999 (95% CI 0.999–1.000) respectively (Figure 2). Discussion Early identification of COVID-19 suspected cases is critical for effective surveillance and successful containment of disease spread. Cases who are not diagnosed correctly and in a timely manner may lead to further transmission of the virus [21] . However, rapid, sensitive, and affordable point-of-care screening tests are yet to be available [22] . To ensure that suspected cases are detected as early as possible, primary care physicians who serve as the first point of contact in the healthcare system need a reliable predictive tool to differentiate COVID-19 from other viral infections such as influenza and dengue at the first presentation. In this study, we built logistic regression models using clinical features and simple laboratory investigations to differentiate COVID-19 from influenza and dengue (Tables 4 and 5). In view of the lower sensitivity of flu model 1 when only symptoms were considered for differentiation of COVID-19 from influenza (Figure 1), it is important to consider full blood count for further assessment where appropriate. Decision algorithms for differentiating dengue, influenza and other febrile illnesses have been reported before [23] . There were a few studies on prediction models for diagnosis of COVID-19, however, these included measurement of cytokines, computed tomography scan or genome sequencing [24] . Recently, Sun et al has come up with algorithms for estimating the risk of COVID-19 among all patients who presented at NCID, which comprised a smaller number of the same cohort of COVID-19 cases in our study, but the duration of symptom onset was not taken into consideration and controls included all SARS-CoV-2 negative patients regardless of final diagnosis [25] . Sun et al found that the AUC of the logistic regression model that predicted COVID-19 was 0.65 when only demographics and clinical variables were considered. When laboratory and exposure-risk variables were included, the models had higher AUCs of 0.88 to 0.91 25 . As our study relied on simple parameters to differentiate COVID-19 from influenza and dengue, the predictors identified from the multivariable logistic regression models may guide primary care physicians, who serve as the first point of contact with the healthcare system, in deciding who should be tested with RT-PCR especially in the absence of travel history to high-risk countries and epidemiological links 16 . In countries and remote regions where confirmatory diagnostic capabilities are limited [26] , clinical features and simple laboratory parameters identified in this study may be used as one of the criteria for isolation of suspected cases to prevent further transmission arising from prolonged delay from symptom onset to isolation [27] . There are a few limitations in our study. We included patients who presented to hospital within 5 days of symptom onset, hence the findings may not be applicable to those presented late for medical care. Patients who were not suspected or sufficiently ill to be referred to hospitals were excluded. There may be differences in clinical and laboratory parameters among dengue patients by virus serotypes, and influenza patients by the circulating virus strains. Two COVID-19 cases co-infected with dengue were reported thus far; one in Singapore and one in Thailand [28] , [29] . Case series of pneumonia patients co-infected with COVID-19 and influenza was also reported in China [30] . There is a need for separate studies to assess such cases, as it would be more challenging to identify co-infections based on their presenting symptoms and simple laboratory markers. In conclusion, we have shown that multivariable models based on clinical features and simple laboratory markers for differentiating COVID-19 from influenza and dengue, which possess good predictive performance can serve as a useful tool for primary care physicians to determine if further investigations or referrals would be required. The findings from our study would need to be further validated, so as to address the knowledge gaps of the ongoing COVID-19 pandemic. Declarations Data availability The datasets analysed during the current study are available from the corresponding author on reasonable request. Acknowledgement This study was supported by National Medical Research Council, Singapore. Author Contributions Y.S.L. and D.C.L. designed the study. T.L.T. and L.W.A. reviewed literature. T.L.T., B.Y. and M.I.C. extracted data. L.W.A. analysed data. T.L.T., L.W.A., M.I.C., Y.S.L. and D.C.L. interpreted the data. T.L.T. and L.W.A. wrote the drafts of the manuscript. B.Y., M.I.C., Y.S.L. and D.C.L. commented on and helped revise the manuscript. All authors read and approved the final manuscript. Competing interest Dr. Young reports personal fees from Sanofi and Roche, outside the submitted work. All other authors have no potential competing interest. References Zhou, P. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579 , 270–273 (2020). World Health Organization. Coronavirus disease 2019 (COVID-19) Situation Report 52. (2020). Available at: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200312-sitrep-52-covid-19.pdf?sfvrsn=e2bfc9c0_4 . (Accessed: 27th May 2020). Young, B. E. et al. Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. JAMA . doi:10.1001/jama.2020.3204 (2020). Wu, Z. & McGoogan, J. M. 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Demographics of COVID-19, influenza and dengue patients COVID-19 (N=126) Influenza (N=171) P -value Dengue (N=180) P -value Age, median (IQR) 52 (37–62) 30 (22–40) <0.0005 36 (29–43) <0.0005 Male, n (%) 74 (58.7) 98 (57.3) 0.813 153 (85.0) <0.0005 Co-morbidity, n (%) 26 (20.6) 31 (18.1) 0.655 18 (10.0) 0.012 Diabetes 15 (11.9) 1 (0.6) <0.0005 1 (0.6) <0.0005 Chronic obstructive pulmonary disease (COPD)/Asthma 4 (3.2) 8 (4.7) 0.569 0 (0.0) 0.027 Myocardial infarction 7 (5.6) - - 1 (0.6) 0.009 Malignancies 2 (1.6) - - 0 (0.0) 0.167 Chronic liver disease 1 (0.8) - - 0 (0.0) 0.410 Chronic renal disease 1 (0.8) - - 0 (0.0) 0.410 IQR, interquartile range, ‘-‘ indicates data is not available. All P values shown are for comparison with COVID-19, based on Fisher’s exact test for categorical variables and Mann-Whitney U test for continuous variables. ^None of the COVID-19 and dengue patients had congestive heart failure, peripheral vascular disease, stroke or dementia, while these comorbid conditions were not recorded for influenza patients. Table 2. Clinical features at presentation of COVID-19, influenza and dengue patients Clinical feature, n (%) COVID-19 (N=126) Influenza (N=171) P -value Dengue (N=180) P -value Fever 86 (68.3) 155 (90.6) <0.0005 180 (100.0) <0.0005 Cough 82 (65.1) 139 (81.3) 0.002 44 (24.4) <0.0005 Shortness of breath 17 (13.5) 1 (0.6) <0.0005 8 (4.4) 0.005 Running nose 30 (23.8) 97 (56.7) <0.0005 14 (7.8) <0.0005 Sore throat 48 (38.1) 97 (56.7) 0.002 39 (21.7) 0.002 Diarrhoea 16 (12.7) 2 (1.2) <0.0005 68 (37.8) <0.0005 Muscle aches 26 (20.6) 31 (18.1) 0.655 137 (76.1) <0.0005 Fatigue/malaise 12 (9.5) 8 (4.7) 0.107 161 (89.4) <0.0005 Abdominal pain 1 (0.8) 3 (1.8) 0.64 32 (17.8) <0.0005 Bleeding 0 (0.0) - - 56 (31.1) <0.0005 Chest pain 2 (1.6) - - 10 (5.6) 0.132 Conjunctivitis 0 (0.0) - - 8 (4.4) 0.023 Headache 13 (10.3) 29 (17.0) 0.129 153 (85.0) <0.0005 Joint pain 1 (0.8) - - 111 (61.7) <0.0005 Skin rash 0 (0.0) - - 54 (30.0) <0.0005 Vomiting/nausea 5 (4.0) 8 (4.7) 1.000 130 (72.2) <0.0005 OR, odds ratio; CI, confidence interval, ‘-‘ indicates data is not available. All P values shown are for comparison with coronavirus disease 2019 (COVID-19), based on Fisher’s exact test. Table 3. Vital signs and laboratory parameters of COVID-19, influenza and dengue patients Value, median (IQR) COVID-19 (N=126) Influenza (N=171) P -value Dengue (N=180) P -value Vital signs at presentation Temperature, ◦ C 37.7 (37.1–38.1) 38.2 (37.6–38.7) <0.0005 37.5 (37.0–38.1) 0.547 Heart rate, beats per minute 89.0 (80.0–99.8) 103 (95–115) <0.0005 75 (66–84) <0.0005 Respiratory rate, breaths per minute 18.0 (17.0–19.0) - - 18 (18–18) 0.715 Systolic blood pressure (mmHg) 133.0 (121.0–146.0) 111 (103–123) <0.0005 119 (110–128) <0.0005 Diastolic blood pressure (mmHg) 80.0 (73.0–88.0) 68 (60–75) <0.0005 72 (65–80) <0.0005 Pulse oximeter O2 saturation (%) 98.0 (97.0–99.0) - - 99 (98–100) <0.0005 Baseline laboratory investigations WBC count, x 10 9 /L 4.7 (3.9–5.9) 6.8 (5.6–8.0) <0.0005 2.5 (2.0–3.2) <0.0005 Haemoglobin, g/dL 14.2 (13.0–15.1) 14.0 (13.0–14.9) 0.342 15.1 (14.1–15.9) <0.0005 Haematocrit, % 42.1 (38.7–44.4) - - 44.0 (41.4–46.6) <0.0005 Platelet count, x 10 9 /L 200.5 (168.5–237.5) 210.0 (171.0–260.0) 0.066 97.5 (73.0–119.0) <0.0005 Neutrophil count, x 10 9 /L 2.7 (2.0–4.1) 5.0 (3.5–6.3) <0.0005 1.5 (1.1–2.0) <0.0005 Lymphocyte count, x 10 9 /L 1.2 (0.9–1.5) 0.9 (0.7–1.3) <0.0005 0.6 (0.4–0.8) <0.0005 Albumin, g/L 41.0 (38.0–43.0) 40.0 (38.0–42.0) 0.463 39.0 (37.0–42.0) 0.044 ALT, U/L 28.0 (19.0–44.8) 20.0 (15.0–32.5) <0.0005 31.0 (22.0–52.0) 0.062 AST, U/L 26.5 (19.0–36.3) 24.0 (20.0–30.0) 0.271 47.0 (32.0–77.8) <0.0005 Creatinine, µmol/L 70.0 (59.0–89.0) 82.0 (67.3–98.0) <0.0005 76.0 (68.0–88.8) 0.011 IQR, interquartile range; ALT, alanine aminotransferase; AST, aspartate aminotransferase, WBC, white blood cell ‘-‘ indicates data is not available. All P values shown are for comparison with coronavirus disease 2019 (COVID-19), based on Mann-Whitney U test for continuous variables. Table 4. Final covariates in multivariable logistic regression models for differentiating COVID-19 versus influenza Variable Flu model 1 Flu model 2 aOR (95% CI) P -value aOR (95% CI) P -value Age 1.09 (1.07–1.12) <0.0005 1.10 (1.07–1.13) <0.0005 Fever 0.22 (0.09–0.48) <0.0005 0.44 (0.18–1.05) 0.067 Cough 0.31 (0.15–0.63) 0.001 0.32 (0.14–0.72) 0.007 Shortness of breath 18.29 (2.28–411.81) 0.018 50.66 (3.09–1,391.20) 0.007 Running nose 0.30 (0.15–0.56) <0.0005 0.31 (0.15–0.62) 0.001 Diarrhoea 13.70 (2.33–128.89) 0.009 8.59 (1.67–67.62) 0.018 Vomiting/nausea 0.11 (0.01–0.73) 0.031 0.19 (0.02–1.29) 0.120 Neutrophil count, x 10 9 /L 0.69 (0.57–0.82) <0.0005 Lymphocyte count, x 10 9 /L 1.93 (1.09–3.46) 0.025 aOR, adjusted odds ratio shown as odds of having COVID-19, CI, confidence interval Table 5. Final covariates in multivariable logistic regression models for differentiating COVID-19 versus dengue Variable Dengue model 1 Dengue model 2 aOR (95% CI) P -value aOR (95% CI) P -value Age 1.06 (1.01–1.12) 0.017 Fever 0.09 (0.00–0.86) 0.034 Headache 0.04 (0.007–0.15) 0.000 0.01 (0.00002–0.09) <0.0005 Cough 51.48 (4.47–4662.18) <0.0005 Joint pain 0.01 (0.001–0.11) <0.0005 0.02 (0.0001–0.26) 0.001 Skin rash 0.02 (0.0001–0.38) 0.007 0.01 (0.00001–0.22) 0.002 Vomiting/nausea 0.02 (0.002–0.11) 0.000 0.001 (0.0000001–0.08) <0.0005 Bleeding 0.01 (0.0001–0.21) 0.002 Platelet count, x 10 9 /L 1.04 (1.01–1.09) 0.001 Lymphocyte count, x 10 9 /L 213.28 (9.65–98,867.53) <0.0005 aOR, adjusted odds ratio shown as odds of having COVID-19 , CI, confidence interval Supplementary Files COVID19influenzaanddengueSupplementarytable.docx Cite Share Download PDF Status: Published Journal Publication published 05 Oct, 2021 Read the published version in Scientific Reports → Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-36343","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":686154,"identity":"d9034671-57f3-4429-abfd-fd704ea9fe71","order_by":1,"name":"Tun-Linn Thein","email":"","orcid":"https://orcid.org/0000-0002-5254-032X","institution":"National Centre for Infectious Diseases","correspondingAuthor":false,"prefix":"","firstName":"Tun-Linn","middleName":"","lastName":"Thein","suffix":""},{"id":686155,"identity":"5a4a2f64-a28f-4bc6-bbe2-8172e10f1903","order_by":2,"name":"Li Wei Ang","email":"","orcid":"https://orcid.org/0000-0002-0036-255X","institution":"National Centre for Infectious Diseases","correspondingAuthor":false,"prefix":"","firstName":"Li","middleName":"Wei","lastName":"Ang","suffix":""},{"id":686156,"identity":"4e3f777c-b557-49c3-874b-9efc46bd9b8f","order_by":3,"name":"Barnaby Edward Young","email":"","orcid":"https://orcid.org/0000-0003-1010-2230","institution":"National Centre for Infectious Diseases\t","correspondingAuthor":false,"prefix":"","firstName":"Barnaby","middleName":"Edward","lastName":"Young","suffix":""},{"id":686157,"identity":"f351663f-29e2-465c-bf8a-a5d0bdac8e21","order_by":4,"name":"Mark IC Chen","email":"","orcid":"https://orcid.org/0000-0001-9369-5830","institution":"National Centre for Infectious Diseases\t","correspondingAuthor":false,"prefix":"","firstName":"Mark","middleName":"IC","lastName":"Chen","suffix":""},{"id":686164,"identity":"867b68cc-6a8d-4d57-a77e-c70107ad7024","order_by":5,"name":"Yee-Sin Leo","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA50lEQVRIie3RsWvCQBTH8V84yC2vZH1FxH/hQSG49V9RCnHJEHCstAeCjq79cyKBuDi465DJSVBwyeDQaywdL3YTvO9wd8N9cjwC+Hx3mORAUIs92L0CODC3EEVXouQm8mxvqMYCIdu9nUR6mitkO4ielu/ZpN810WrjJCGVAzvLHkJlsv0q+cVwmrkJpwKSAsJpvH0yPDRMAzfpHU9X0jvE44ZE6xbChN9XKFYNwShvmSUR1RBK3jpkZ5lx6hQIdVEF9aXA67xYnmny0V1Eq8ptAF3b5dP8fQQ/f/af6dZXfD6f77H6Bj1BPMOxpppjAAAAAElFTkSuQmCC","orcid":"https://orcid.org/0000-0003-4978-5825","institution":"National Centre for Infectious Diseases\t","correspondingAuthor":true,"prefix":"","firstName":"Yee-Sin","middleName":"","lastName":"Leo","suffix":""},{"id":686165,"identity":"07bfe8b5-3f88-44af-b4a0-8d4c924b1348","order_by":6,"name":"David Chien Lye","email":"","orcid":"https://orcid.org/0000-0003-0324-0205","institution":"National Centre for Infectious Diseases\t","correspondingAuthor":false,"prefix":"","firstName":"David","middleName":"Chien","lastName":"Lye","suffix":""}],"badges":[],"createdAt":"2020-06-18 10:13:03","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-36343/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-36343/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1038/s41598-021-99027-z","type":"published","date":"2021-10-05T14:56:43+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":1364577,"identity":"081970a9-05c8-467a-b0ca-24a05af3e60a","added_by":"auto","created_at":"2020-06-18 22:03:30","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":160026,"visible":true,"origin":"","legend":"Receiver operating characteristic curves for flu model 1 (demographics and symptoms) and model 2 (demographics, symptoms and laboratory parameters) for differentiating COVID-19 versus influenza","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-36343/v1/1.png"},{"id":1364578,"identity":"0a0749e4-84f9-47eb-b030-f108db28bfba","added_by":"auto","created_at":"2020-06-18 22:03:30","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":140050,"visible":true,"origin":"","legend":"Receiver operating characteristic curves for dengue model 1 (demographics and symptoms) and model 2 (demographics, symptoms and laboratory parameters) for differentiating COVID-19 versus dengue","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-36343/v1/2.png"},{"id":14261845,"identity":"c6aef92a-2525-4222-9ba9-cfc029a3256a","added_by":"auto","created_at":"2021-10-05 14:56:47","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":613070,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-36343/v1/79cc9e9b-ac3d-4c01-b512-74cd9ac86d65.pdf"},{"id":1364580,"identity":"91ed6d2d-40e3-4961-831c-e37057f6cfed","added_by":"auto","created_at":"2020-06-18 22:03:30","extension":"docx","order_by":1,"title":"","display":"","copyAsset":false,"role":"supplement","size":29136,"visible":true,"origin":"","legend":"","description":"","filename":"COVID19influenzaanddengueSupplementarytable.docx","url":"https://assets-eu.researchsquare.com/files/rs-36343/v1/COVID19influenzaanddengueSupplementarytable.docx"}],"financialInterests":"","formattedTitle":"\u003cp\u003eDifferentiating coronavirus disease 2019 (COVID-19) from influenza and dengue\u003c/p\u003e","fulltext":[{"header":"Introduction","content":"\u003cp\u003eA cluster of cases of pneumonia with unknown cause was detected in Wuhan in December 2019\u003csup\u003e\u003ca href=\"#_edn1\" name=\"_ednref1\"\u003e[1]\u003c/a\u003e\u003c/sup\u003e. Caused by a novel human coronavirus now named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it has since spread rapidly on a global scale. On 11 March 2020, the World Health Organization (WHO) declared the novel coronavirus disease (COVID-19) as a pandemic, and expressed deep concern about the alarming levels of spread and severity\u003csup\u003e\u003ca href=\"#_edn2\" name=\"_ednref2\"\u003e[2]\u003c/a\u003e\u003c/sup\u003e. Confirmation of acute SARS-CoV-2 infection requires detection of the virus in respiratory samples by reverse transcriptase polymerase chain reaction (RT-PCR) test. Clinical presentation of COVID-19 patients ranges from asymptomatic to mild non-specific acute symptoms such as fever, dry cough and fatigue\u003csup\u003e\u003ca href=\"#_edn3\" name=\"_ednref3\"\u003e[3]\u003c/a\u003e\u003c/sup\u003e. Close to 20% of COVID-19 cases may be severe\u003csup\u003e\u003ca href=\"#_edn4\" name=\"_ednref4\"\u003e[4]\u003c/a\u003e\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eInfluenza is prevalent globally and remains an important cause of morbidity and mortality from respiratory viral infections\u003csup\u003e\u003ca href=\"#_edn5\" name=\"_ednref5\"\u003e[5]\u003c/a\u003e\u003c/sup\u003e while dengue is prevalent in tropical countries with geographic expansion\u003csup\u003e\u003ca href=\"#_edn6\" name=\"_ednref6\"\u003e[6]\u003c/a\u003e\u003c/sup\u003e. Dengue is also known as not only the leading cause of fever in returning travelers in non-endemic countries, but also the main source for triggering autochthonous transmissions\u003csup\u003e\u003ca href=\"#_edn7\" name=\"_ednref7\"\u003e[7]\u003c/a\u003e,\u003ca href=\"#_edn8\" name=\"_ednref8\"\u003e[8]\u003c/a\u003e\u003c/sup\u003e. Since clinical presentations of these common viral infections are non-specific, it is difficult for primary care physicians to differentiate COVID-19 from influenza and dengue. This may result in misdiagnosis or delayed diagnosis, and lead to further transmission in the community. As the COVID-19 pandemic progresses, doctors in both dengue endemic\u003csup\u003e\u003ca href=\"#_edn9\" name=\"_ednref9\"\u003e[9]\u003c/a\u003e,\u003ca href=\"#_edn10\" name=\"_ednref10\"\u003e[10]\u003c/a\u003e,\u003ca href=\"#_edn11\" name=\"_ednref11\"\u003e[11]\u003c/a\u003e\u003c/sup\u003e and non-endemic countries where influenza may be the most relevant differential diagnosis for COVID-19\u003csup\u003e5\u003c/sup\u003e\u003csup\u003e,\u003ca href=\"#_edn12\" name=\"_ednref12\"\u003e[12]\u003c/a\u003e\u003c/sup\u003e, should maintain a high level of suspicion and be provided with effective tools to differentiate these three infections.\u003c/p\u003e\n\u003cp\u003eSingapore is a tropical city state with several endemic viral infections. Influenza circulates year round with bimodal peaks typically observed in April-July and November-January\u003csup\u003e\u003ca href=\"#_edn13\" name=\"_ednref13\"\u003e[13]\u003c/a\u003e\u003c/sup\u003e. Dengue epidemics of increasing magnitude have occurred in a five- to six-year cycle affecting more adults than children\u003csup\u003e\u003ca href=\"#_edn14\" name=\"_ednref14\"\u003e[14]\u003c/a\u003e\u003c/sup\u003e. As of 15 Jun 2020, a total of 40,818 cases of the COVID-19 including 26 deaths have been reported in Singapore\u003csup\u003e\u003ca href=\"#_edn15\" name=\"_ednref15\"\u003e[15]\u003c/a\u003e\u003c/sup\u003e. It is of concern that two local cases of COVID-19 with false positive dengue serology were reported in Singapore without travel or contact history\u003csup\u003e\u003ca href=\"#_edn16\" name=\"_ednref16\"\u003e[16]\u003c/a\u003e\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eIn this study, we compared clinical presentations and laboratory parameters of patients with COVID-19, influenza and dengue. We constructed predictive models using logistic regression with the aim to assist doctors in differentiating COVID-19 from influenza and dengue based on clinical features and simple laboratory investigations.\u003c/p\u003e"},{"header":"Methods","content":"\u003cp\u003e\u003cstrong\u003eCohort description\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eOur study population comprised laboratory confirmed COVID-19 from an ongoing prospective cohort, and influenza and dengue patients from previous studies. Briefly, prospective recruitment of COVID-19 patients took place from January to April 2020 at the National Centre for Infectious Diseases (NCID), Singapore\u003csup\u003e3\u003c/sup\u003e. Influenza patients were selected from a retrospective study of those who presented at Tan Tock Seng Hospital (TTSH), the primary centre for screening, treatment and isolation of H1N1(pdm09) cases from April to June 2009 in Singapore\u003csup\u003e\u003ca href=\"#_edn1\" name=\"_ednref1\"\u003e[17]\u003c/a\u003e\u003c/sup\u003e. Dengue patients were selected from a prospective cohort study where adult patients presented with acute undifferentiated febrile illness to TTSH from January 2010 to September 2012\u003csup\u003e\u003ca href=\"#_edn2\" name=\"_ednref2\"\u003e[18]\u003c/a\u003e\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eAt first presentation to the hospital, demographic data, symptoms and signs were collected. Full blood count, renal and liver function tests were performed. SARS-CoV-2, influenza and dengue viruses were detected in respiratory samples or venous blood by RT-PCR tests\u003csup\u003e3\u003c/sup\u003e\u003csup\u003e,\u003c/sup\u003e\u003csup\u003e17\u003c/sup\u003e\u003csup\u003e,\u003c/sup\u003e\u003csup\u003e18\u003c/sup\u003e. Data of 215 patients with COVID-19, 200 with H1N1(pdm09) or seasonal influenza, and 300 with dengue (predominantly dengue virus serotype 2) were extracted. As our objective was to derive early predictors to differentiate COVID-19 from influenza and dengue, we analysed only symptomatic patients who presented to hospital within 5 days after symptom onset.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthics\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eData for COVID-19 cohort was collected with waiver of informed consent granted by Ministry of Health, Singapore, under the Infectious Diseases Act as part of COVID-19 outbreak investigation. Research samples and data for the prospective COVID-19 and dengue cohort studies were collected with written informed consent approved by the Domain Specific Review Board (DSRB) of the National Healthcare Group, Singapore (DSRB/ E/12/917 and DSRB/E/09/432). Waiver of informed consent was approved for the retrospective study for influenza patients by the same review board (DSRB/E/09/344).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eStatistical analysis\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFisher\u0026rsquo;s exact test was used to compare categorical variables and Mann-Whitney U test to compare continuous variables between any two groups. All statistical tests were two-sided, and statistical significance was taken as \u003cem\u003eP \u0026lt; \u003c/em\u003e0.05.\u003c/p\u003e\n\u003cp\u003eWe used multivariable logistic regression models as predictive tools to differentiate between COVID-19 and influenza, and COVID-19 and dengue. We followed the transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD) 2015 guideline\u003csup\u003e\u003ca href=\"#_edn3\" name=\"_ednref3\"\u003e[19]\u003c/a\u003e\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eTwo multivariable models were fitted for differentiating COVID-19 versus influenza (flu models 1 and 2) and COVID-19 versus dengue (dengue models 1 and 2): flu model 1 and dengue model 1 contained demographics and symptoms, whereas flu model 2 and dengue model 2 included laboratory parameters in addition to demographics and symptoms.\u003c/p\u003e\n\u003cp\u003eFor the analysis on COVID-19 versus influenza, the proportion of missing data for laboratory parameters ranged from 3.4% (10 out of total 297 observations) for WBC count, haemoglobin, platelet, neutrophil count and lymphocyte count, to 28.3% (84 observations) for albumin, alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The variables for flu models 1 and 2 were selected through stepwise use of Akaike\u0026rsquo;s information criterion. Multicollinearity was then checked using variance inflation factor (VIF) for the final predictor variables included in these 2 multivariable models, which ranged from 1.01 to 1.25.\u003c/p\u003e\n\u003cp\u003eFor the analysis on COVID-19 versus dengue, the proportion of missing data for laboratory parameters ranged from 3.3% (10 out of total 306 observations) for WBC count, haemoglobin, haematocrit, platelet, neutrophil count and lymphocyte count, to 9.2% (28 observations) for AST. As the data for differentiating COVID-19 versus dengue exhibited separation, finite estimates of adjusted odds ratios (aOR) and Wald confidence intervals (CI) could not be obtained. Hence, we applied Firth\u0026rsquo;s modified score procedure to estimate OR and derived CI using the profile-penalized likelihood function\u003csup\u003e\u003ca href=\"#_edn4\" name=\"_ednref4\"\u003e[20]\u003c/a\u003e\u003c/sup\u003e. The variables in dengue models 1 and 2 were selected by backward stepwise approach using penalized likelihood ratio tests. The VIF for the final predictor variables ranged from 1.01 to 1.23 for dengue model 1, and it ranged from 1.31 to 3.67 in dengue model 2 when laboratory parameters were included.\u003c/p\u003e\n\u003cp\u003eWe assessed the predictive performance of the multivariable logistic regression models using receiver operating characteristic (ROC) curves and the corresponding area under the ROC (AUC).\u003c/p\u003e\n\u003cp\u003e\u003ca href=\"#_ednref1\" name=\"_edn1\"\u003e\u003c/a\u003e\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003eThis study comprised 126 patients with COVID-19, 171 with influenza and 180 with dengue, who presented within 5 days after symptom onset. The demographic characteristics of the patients are shown in Table 1. The age of COVID-19 patients was older compared with influenza and dengue patients. A lower proportion of COVID-19 patients were male compared with dengue patients. The proportion of COVID-19 patients having comorbidities was higher compared with dengue patients but not with influenza patients.\u003c/p\u003e\n\u003cp\u003eThe clinical features of patients with COVID-19, influenza and dengue at presentation are shown in Table 2. Shortness of breath and diarrhoea were more common in COVID-19 patients than in influenza patients, while fever, cough, running nose and sore throat were less common. Cough, shortness of breath, running nose and sore throat were more common in COVID-19 patients than in dengue patients. A lower proportion of COVID-19 patients had fever, diarrhoea, muscle aches, fatigue/malaise, abdominal pain, bleeding, conjunctivitis, headache, joint pain, skin rash and vomiting/nausea compared with dengue patients. We also provided an infographic of percentage of COVID-19, influenza and dengue patients with each symptom at presentation. It can be seen that COVID-19 and influenza patients have similar symptoms, while dengue patients present with symptoms that are significantly different from the other two groups (See Supplementary Table S1).\u003c/p\u003e\n\u003cp\u003eThe vital signs and laboratory parameters of patients with COVID-19, influenza and dengue are shown in Table 3. COVID-19 patients had lower white blood cell (WBC) count, neutrophil count and creatinine compared with influenza patients whereas their lymphocyte count and alanine aminotransferase (ALT) were higher. WBC, platelet, neutrophil and lymphocyte counts and albumin were higher in COVID-19 patients than dengue patients. The haemoglobin, haematocrit, aspartate aminotransferase (AST) and creatinine were lower in COVID-19 patients than dengue patients.\u003c/p\u003e\n\u003cp\u003eThe multivariable logistic regressions differentiating COVID-19 from influenza are shown in Table 4. In flu model 1 containing demographics and symptoms, older age (aOR 1.09; 95% CI: 1.07\u0026ndash;1.12), shortness of breath (aOR 18.29; 95% CI: 2.28\u0026ndash;411.81) and diarrhoea (aOR 13.70; 95% CI: 2.33\u0026ndash;128.89) increased the odds that the patient had COVID-19, while fever, cough, running nose and vomiting/nauseas were indicative of influenza. In flu model 2 containing demographics, symptoms and laboratory parameters, older age (aOR 1.10; 95% CI: 1.07\u0026ndash;1.13), shortness of breath (aOR 50.66; 95% CI: 3.09\u0026ndash;1391.20), diarrhoea ((aOR 8.59; 95% CI: 1.67\u0026ndash;67.62) and higher lymphocyte count (aOR 1.93; 95% CI: 1.09\u0026ndash;3.46) were predictive of COVID-19, while cough, running nose and lower neutrophil count were indicative of influenza.\u003c/p\u003e\n\u003cp\u003eTable 5 shows the multivariable logistic regression analysis differentiating COVID-19 versus dengue. In dengue model 1 containing demographics and symptoms, older age (aOR 1.06; 95% CI: 1.01\u0026ndash;1.12) increased the odds that the patient had COVID-19, while fever, headache, joint pain, skin rash, vomiting/nauseas and bleeding were indicative of dengue. In dengue model 2 containing demographics, symptoms and laboratory parameters, patients who had cough (aOR 51.48; 95% CI: 4.47\u0026ndash;4,662.18), higher platelet count (aOR 1.04; 95% CI: 1.01\u0026ndash;1.09) and higher lymphocyte count (aOR 213.28; 95% CI: 9.65\u0026ndash;98867.53) were at increased odds of COVID-19, while cough, headache, joint pain, skin rash and vomiting/nauseas were indicative of dengue.\u003c/p\u003e\n\u003cp\u003eThe AUC of flu model 1 containing demographics and symptoms was 0.893 (95% CI 0.856\u0026ndash;0.931), and the AUC of flu model 2 which included laboratory parameters in differentiating COVID-19 versus influenza was 0.920 (95% CI 0.888\u0026ndash;0.953) (Figure 1). The AUC of dengue model 1 without laboratory parameters and of dengue model 2 which included laboratory parameters for differentiating COVID-19 versus dengue were 0.995 (95% CI 0.992\u0026ndash;1.000) and 0.999 (95% CI 0.999\u0026ndash;1.000) respectively (Figure 2).\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eEarly identification of COVID-19 suspected cases is critical for effective surveillance and successful containment of disease spread. Cases who are not diagnosed correctly and in a timely manner may lead to further transmission of the virus\u003csup\u003e\u003ca href=\"#_edn1\" name=\"_ednref1\"\u003e[21]\u003c/a\u003e\u003c/sup\u003e. However, rapid, sensitive, and affordable point-of-care screening tests are yet to be available\u003csup\u003e\u003ca href=\"#_edn2\" name=\"_ednref2\"\u003e[22]\u003c/a\u003e\u003c/sup\u003e. To ensure that suspected cases are detected as early as possible, primary care physicians who serve as the first point of contact in the healthcare system need a reliable predictive tool to differentiate COVID-19 from other viral infections such as influenza and dengue at the first presentation.\u003c/p\u003e\n\u003cp\u003eIn this study, we built logistic regression models using clinical features and simple laboratory investigations to differentiate COVID-19 from influenza and dengue (Tables 4 and 5). In view of the lower sensitivity of flu model 1 when only symptoms were considered for differentiation of COVID-19 from influenza (Figure 1), it is important to consider full blood count for further assessment where appropriate.\u003c/p\u003e\n\u003cp\u003eDecision algorithms for differentiating dengue, influenza and other febrile illnesses have been reported before\u003csup\u003e\u003ca href=\"#_edn3\" name=\"_ednref3\"\u003e[23]\u003c/a\u003e\u003c/sup\u003e. There were a few studies on prediction models for diagnosis of COVID-19, however, these included measurement of cytokines, computed tomography scan or genome sequencing\u003csup\u003e\u003ca href=\"#_edn4\" name=\"_ednref4\"\u003e[24]\u003c/a\u003e\u003c/sup\u003e. Recently, Sun et al has come up with algorithms for estimating the risk of COVID-19 among all patients who presented at NCID, which comprised a smaller number of the same cohort of COVID-19 cases in our study, but the duration of symptom onset was not taken into consideration and controls included all SARS-CoV-2 negative patients regardless of final diagnosis\u003csup\u003e\u003ca href=\"#_edn5\" name=\"_ednref5\"\u003e[25]\u003c/a\u003e\u003c/sup\u003e. Sun et al found that the AUC of the logistic regression model that predicted COVID-19 was 0.65 when only demographics and clinical variables were considered. When laboratory and exposure-risk variables were included, the models had higher AUCs of 0.88 to 0.91\u003csup\u003e25\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eAs our study relied on simple parameters to differentiate COVID-19 from influenza and dengue, the predictors identified from the multivariable logistic regression models may guide primary care physicians, who serve as the first point of contact with the healthcare system, in deciding who should be tested with RT-PCR especially in the absence of travel history to high-risk countries and epidemiological links\u003csup\u003e16\u003c/sup\u003e. In countries and remote regions where confirmatory diagnostic capabilities are limited\u003csup\u003e\u003ca href=\"#_edn6\" name=\"_ednref6\"\u003e[26]\u003c/a\u003e\u003c/sup\u003e, clinical features and simple laboratory parameters identified in this study may be used as one of the criteria for isolation of suspected cases to prevent further transmission arising from prolonged delay from symptom onset to isolation\u003csup\u003e\u003ca href=\"#_edn7\" name=\"_ednref7\"\u003e[27]\u003c/a\u003e\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eThere are a few limitations in our study. We included patients who presented to hospital within 5 days of symptom onset, hence the findings may not be applicable to those presented late for medical care. Patients who were not suspected or sufficiently ill to be referred to hospitals were excluded. There may be differences in clinical and laboratory parameters among dengue patients by virus serotypes, and influenza patients by the circulating virus strains. Two COVID-19 cases co-infected with dengue were reported thus far; one in Singapore and one in Thailand\u003csup\u003e\u003ca href=\"#_edn8\" name=\"_ednref8\"\u003e[28]\u003c/a\u003e,\u003ca href=\"#_edn9\" name=\"_ednref9\"\u003e[29]\u003c/a\u003e\u003c/sup\u003e. Case series of pneumonia patients co-infected with COVID-19 and influenza was also reported in China\u003csup\u003e\u003ca href=\"#_edn10\" name=\"_ednref10\"\u003e[30]\u003c/a\u003e\u003c/sup\u003e. There is a need for separate studies to assess such cases, as it would be more challenging to identify co-infections based on their presenting symptoms and simple laboratory markers.\u003c/p\u003e\n\u003cp\u003eIn conclusion, we have shown that multivariable models based on clinical features and simple laboratory markers for differentiating COVID-19 from influenza and dengue, which possess good predictive performance can serve as a useful tool for primary care physicians to determine if further investigations or referrals would be required. The findings from our study would need to be further validated, so as to address the knowledge gaps of the ongoing COVID-19 pandemic.\u003c/p\u003e\n\u003cp\u003e\u003ca href=\"#_ednref1\" name=\"_edn1\"\u003e\u003c/a\u003e\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eData availability\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe datasets analysed during the current study are available from the corresponding author on reasonable request.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcknowledgement\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study was supported by National Medical Research Council, Singapore.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthor Contributions\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eY.S.L. and D.C.L. designed the study. T.L.T. and L.W.A. reviewed literature. T.L.T., B.Y. and M.I.C. extracted data. L.W.A. analysed data. T.L.T., L.W.A., M.I.C., Y.S.L. and D.C.L. interpreted the data. T.L.T. and L.W.A. wrote the drafts of the manuscript. B.Y., M.I.C., Y.S.L. and D.C.L. commented on and helped revise the manuscript. All authors read and approved the final manuscript.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCompeting interest\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eDr. Young reports personal fees from Sanofi and Roche, outside the submitted work. All other authors have no potential competing interest.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli class=\"p1\"\u003eZhou, P. \u003cem\u003eet al.\u003c/em\u003e A pneumonia outbreak associated with a new coronavirus of probable bat origin. \u003cem\u003eNature\u003c/em\u003e \u003cstrong\u003e579\u003c/strong\u003e, 270\u0026ndash;273 (2020).\u003c/li\u003e\n\u003cli class=\"p1\"\u003eWorld Health Organization. Coronavirus disease 2019 (COVID-19) Situation Report 52. (2020). 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H. \u003cem\u003eet al.\u003c/em\u003e The early clinical features of dengue in adults: challenges for early clinical diagnosis. \u003cem\u003ePLoS Negl Trop Dis\u003c/em\u003e \u003cstrong\u003e5\u003c/strong\u003e, e1191 (2011).\u003c/li\u003e\n\u003cli class=\"p1\"\u003eWynants, L. \u003cem\u003eet al.\u003c/em\u003e Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal. \u003cem\u003eBMJ\u003c/em\u003e \u003cstrong\u003e369\u003c/strong\u003e, m1328 (2020).\u003c/li\u003e\n\u003cli class=\"p1\"\u003eSun, Y. \u003cem\u003eet al.\u003c/em\u003e Epidemiological and Clinical Predictors of COVID-19. \u003cem\u003eClin Infect Dis\u003c/em\u003e doi:10.1093/cid/ciaa322 (2020).\u003c/li\u003e\n\u003cli class=\"p1\"\u003eGilbert, M. \u003cem\u003eet al.\u003c/em\u003e Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study. \u003cem\u003eLancet\u003c/em\u003e \u003cstrong\u003e395\u003c/strong\u003e, 871\u0026ndash;877 (2020).\u003c/li\u003e\n\u003cli class=\"p1\"\u003eHellewell, J. \u003cem\u003eet al.\u003c/em\u003e Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts. \u003cem\u003eLancet Glob Health\u003c/em\u003e \u003cstrong\u003e8\u003c/strong\u003e, e488\u0026ndash;e496 (2020).\u003c/li\u003e\n\u003cli class=\"p1\"\u003eTeo, J. \u0026amp; Zhou, T. Coronavirus: Rare to have Covid-19 and dengue, say experts of Singapore\u0026rsquo;s first patient with both. \u003cem\u003eThe Straits Times\u003c/em\u003e (2020). Available at: \u003ca href=\"https://imsva91-ctp.trendmicro.com:443/wis/clicktime/v1/query?url=https%3a%2f%2fwww.straitstimes.com%2fsingapore%2fhealth%2frare%2dto%2dhave%2dcoronavirus%2dand%2ddengue\u0026amp;umid=9E2CB401-A72A-1E05-AC6A-9221743181E8\u0026amp;auth=6e3fe59570831a389716849e93b5d483c90c3fe4-c2db50327f134d126933fd5741d9b4ce40040d58\"\u003e\u003cspan class=\"s1\"\u003ehttps://www.straitstimes.com/singapore/health/rare-to-have-coronavirus-and-dengue\u003c/span\u003e\u003c/a\u003e (Accessed: 31st March 2020)\u003c/li\u003e\n\u003cli class=\"p1\"\u003eTun, S. Thailand records first coronavirus death: health official. \u003cem\u003eReuters\u003c/em\u003e (2020).\u003c/li\u003e\n\u003cli class=\"p1\"\u003eDing, Q., Lu, P., Fan, Y., Xia, Y. \u0026amp; Liu, M. The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China. \u003cem\u003eJournal of Medical Virology\u003c/em\u003e doi:10.1002/jmv.25781 (2020).\u003c/li\u003e\n\u003c/ol\u003e"},{"header":"tables","content":"\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 11px; line-height: 26.666664123535156px; font-family: Verdana, Geneva, sans-serif; color: rgb(0, 0, 0);\"\u003eTable 1. Demographics of COVID-19, influenza and dengue patients\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 591.25pt;border-collapse: collapse;\" width=\"788\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 19pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"3.1725888324873095%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 179pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.32994923857868%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 99pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eCOVID-19\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=126)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eInfluenza\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=171)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-value\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eDengue\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=180)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-value\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 2.75in;border: none;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"33.50253807106599%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eAge, median (IQR)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;border: none;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e52 (37\u0026ndash;62)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;border: none;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e30 (22\u0026ndash;40)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;border: none;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;border: none;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e36 (29\u0026ndash;43)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;border: none;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 2.75in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"33.50253807106599%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eMale, n (%)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e74 (58.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e98 (57.3)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.813\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e153 (85.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 2.75in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"33.50253807106599%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eCo-morbidity, n (%)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e26 (20.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e31 (18.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.655\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e18 (10.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.012\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 19pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"3.1725888324873095%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 179pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.32994923857868%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eDiabetes\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e15 (11.9)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 19pt;padding: 0in 5.4pt;height: 18.75pt;vertical-align: top;\" valign=\"top\" width=\"3.1725888324873095%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 179pt;padding: 0in 5.4pt;height: 18.75pt;vertical-align: top;\" valign=\"top\" width=\"30.32994923857868%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eChronic obstructive pulmonary disease (COPD)/Asthma\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;padding: 0in 5.4pt;height: 18.75pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e4 (3.2)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;padding: 0in 5.4pt;height: 18.75pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e8 (4.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;padding: 0in 5.4pt;height: 18.75pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.569\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;padding: 0in 5.4pt;height: 18.75pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0 (0.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;padding: 0in 5.4pt;height: 18.75pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.027\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 19pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"3.1725888324873095%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 179pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.32994923857868%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eMyocardial infarction\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e7 (5.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.009\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 19pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"3.1725888324873095%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 179pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.32994923857868%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eMalignancies\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e2 (1.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0 (0.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.167\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 19pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"3.1725888324873095%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 179pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.32994923857868%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eChronic liver disease\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0 (0.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.410\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 19pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"3.1725888324873095%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 179pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.32994923857868%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eChronic renal disease\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 99pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.751269035532996%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.25in;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.228426395939087%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.644670050761421%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 100pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.878172588832488%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0 (0.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47.25pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"7.99492385786802%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.410\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eIQR, interquartile range, \u0026lsquo;-\u0026lsquo; indicates data is not available.\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eAll \u003cem\u003eP\u003c/em\u003e values shown are for comparison with COVID-19, based on Fisher\u0026rsquo;s exact test for categorical variables and Mann-Whitney U test for continuous variables.\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003e^None of the COVID-19 and dengue patients had congestive heart failure, peripheral vascular disease, stroke or dementia, while these comorbid conditions were not recorded for influenza patients.\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eTable 2. Clinical features at presentation of COVID-19, influenza and dengue patients\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 446.45pt;border-collapse: collapse;\" width=\"595\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eClinical feature, n (%)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eCOVID-19\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=126)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eInfluenza\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=171)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-value\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eDengue\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=180)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-value\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eFever\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, 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29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eCough\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e82 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sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.002\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e44 (24.4)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eShortness of breath\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e17 (13.5)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e8 (4.4)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 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width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e48 (38.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e97 (56.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.002\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e39 (21.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.002\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eDiarrhoea\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e16 (12.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e2 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sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e68 (37.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e26 (20.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e31 (18.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.655\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e137 (76.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eFatigue/malaise\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e12 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sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.107\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e161 (89.4)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eAbdominal pain\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e3 (1.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.64\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e32 (17.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 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21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e56 (31.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eChest 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sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e10 (5.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, 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\u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eHeadache\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e13 (10.3)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e29 (17.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.129\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e153 (85.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eJoint pain\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1 (0.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e111 (61.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eSkin rash\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0 (0.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e54 (30.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 106.35pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"23.865546218487395%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eVomiting/nausea\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85.05pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.991596638655462%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e5 (4.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e8 (4.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1.000\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e130 (72.2)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.285714285714286%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eOR, odds ratio; CI, confidence interval, \u0026lsquo;-\u0026lsquo; indicates data is not available.\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eAll \u003cem\u003eP\u003c/em\u003e values shown are for comparison with coronavirus disease 2019 (COVID-19), based on\u0026nbsp;Fisher\u0026rsquo;s exact test.\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eTable 3. Vital signs and laboratory parameters of COVID-19, influenza and dengue patients\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 645pt;border-collapse: collapse;\" width=\"860\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 184.3pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"28.571428571428573%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eValue, median (IQR)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eCOVID-19\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=126)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eInfluenza\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=171)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-value\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eDengue\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e(N=180)\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-value\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 184.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"28.571428571428573%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eVital signs at presentation\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eTemperature, \u003csup\u003e◦\u003c/sup\u003eC\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e37.7 (37.1\u0026ndash;38.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e38.2 (37.6\u0026ndash;38.7)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e37.5 (37.0\u0026ndash;38.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.547\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eHeart rate, beats per minute\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e89.0 (80.0\u0026ndash;99.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e103 (95\u0026ndash;115)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e75 (66\u0026ndash;84)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eRespiratory rate, breaths per minute\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e18.0 (17.0\u0026ndash;19.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e18 (18\u0026ndash;18)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.715\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eSystolic blood pressure (mmHg)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e133.0 (121.0\u0026ndash;146.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e111 (103\u0026ndash;123)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e119 (110\u0026ndash;128)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eDiastolic blood pressure (mmHg)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e80.0 (73.0\u0026ndash;88.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e68 (60\u0026ndash;75)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e72 (65\u0026ndash;80)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003ePulse oximeter O2 saturation (%)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e98.0 (97.0\u0026ndash;99.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e99 (98\u0026ndash;100)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 184.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"28.571428571428573%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eBaseline laboratory investigations\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eWBC count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e4.7 (3.9\u0026ndash;5.9)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e6.8 (5.6\u0026ndash;8.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e2.5 (2.0\u0026ndash;3.2)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eHaemoglobin, g/dL\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e14.2 (13.0\u0026ndash;15.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e14.0 (13.0\u0026ndash;14.9)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.342\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e15.1 (14.1\u0026ndash;15.9)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eHaematocrit, %\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e42.1 (38.7\u0026ndash;44.4)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e-\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e44.0 (41.4\u0026ndash;46.6)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003ePlatelet count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e200.5 (168.5\u0026ndash;237.5)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e210.0 (171.0\u0026ndash;260.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.066\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e97.5 (73.0\u0026ndash;119.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eNeutrophil count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e2.7 (2.0\u0026ndash;4.1)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e5.0 (3.5\u0026ndash;6.3)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1.5 (1.1\u0026ndash;2.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eLymphocyte count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e1.2 (0.9\u0026ndash;1.5)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.9 (0.7\u0026ndash;1.3)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.6 (0.4\u0026ndash;0.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 15.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eAlbumin, g/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e41.0 (38.0\u0026ndash;43.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e40.0 (38.0\u0026ndash;42.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.463\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e39.0 (37.0\u0026ndash;42.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.044\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 11.1pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"1.7421602787456445%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 173.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"26.829268292682926%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eALT, U/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e28.0 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29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e31.0 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29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e26.5 (19.0\u0026ndash;36.3)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e24.0 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sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e47.0 (32.0\u0026ndash;77.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n 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sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003eCreatinine, \u0026micro;mol/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 121.6pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"18.81533101045296%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e70.0 (59.0\u0026ndash;89.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 112.3pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"17.421602787456447%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e82.0 (67.3\u0026ndash;98.0)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.75pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.872241579558652%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 106.35pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"16.492450638792103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e76.0 (68.0\u0026ndash;88.8)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.826945412311266%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e0.011\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eIQR, interquartile range; ALT, alanine aminotransferase; AST, aspartate aminotransferase, WBC, white blood cell\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003e\u0026lsquo;-\u0026lsquo; indicates data is not available.\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eAll \u003cem\u003eP\u003c/em\u003e values shown are for comparison with coronavirus disease 2019 (COVID-19), based on Mann-Whitney U test for continuous variables.\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eTable 4. Final covariates in multivariable logistic regression models for differentiating COVID-19 versus influenza\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 512pt;border-collapse: collapse;\" width=\"683\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 157pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: black;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eVariable\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 171pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"33.43108504398827%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eFlu model 1\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;border-style: solid none none;border-top-width: 1pt;border-top-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 163pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"31.818181818181817%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eFlu model 2\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"13.530655391120508%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eaOR\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"21.141649048625794%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e(95% CI)\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"13.530655391120508%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003eP\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e-value\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"5.919661733615222%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"13.530655391120508%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eaOR\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"18.816067653276956%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e(95% CI)\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 11.9pt;vertical-align: top;\" valign=\"top\" width=\"13.530655391120508%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003eP\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e-value\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eAge\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e1.09\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.662756598240469%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(1.07\u0026ndash;1.12)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e1.10\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"13.049853372434018%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(1.07\u0026ndash;1.13)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n 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11px;\"\u003eFever\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.22\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.662756598240469%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, 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11px;\"\u003e0.001\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eDiarrhoea\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e13.70\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.662756598240469%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(2.33\u0026ndash;128.89)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.009\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e8.59\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"13.049853372434018%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(1.67\u0026ndash;67.62)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.018\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eVomiting/nausea\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.11\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"14.662756598240469%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.01\u0026ndash;0.73)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.031\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.19\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"13.049853372434018%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.02\u0026ndash;1.29)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.120\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eNeutrophil count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"14.662756598240469%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.69\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"13.049853372434018%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.57\u0026ndash;0.82)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eLymphocyte count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"14.662756598240469%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e1.93\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"13.049853372434018%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(1.09\u0026ndash;3.46)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.025\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eaOR, adjusted odds ratio\u0026nbsp;shown as odds of having COVID-19, CI, confidence interval\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 21.333335876464844px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eTable 5. Final covariates in multivariable logistic regression models for differentiating COVID-19 versus dengue\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 512pt;border-collapse: collapse;\" width=\"683\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 157pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: black;background-color: white;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eVariable\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 171pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"33.43108504398827%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eDengue model 1\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;border-style: solid none none;border-top-width: 1pt;border-top-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 163pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"31.818181818181817%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eDengue model 2\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 13.5pt;vertical-align: top;\" valign=\"top\" width=\"13.530655391120508%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eaOR\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.6pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 13.5pt;vertical-align: top;\" valign=\"top\" width=\"21.775898520084567%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e(95% CI)\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.4pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 13.5pt;vertical-align: top;\" valign=\"top\" width=\"12.896405919661733%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003eP\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e-value\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 13.5pt;vertical-align: top;\" valign=\"top\" width=\"5.919661733615222%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 13.5pt;vertical-align: top;\" valign=\"top\" width=\"13.530655391120508%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003eaOR\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.8pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 13.5pt;vertical-align: top;\" valign=\"top\" width=\"19.873150105708245%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e(95% CI)\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.2pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;background-color: white;padding: 0in 5.4pt;height: 13.5pt;vertical-align: top;\" valign=\"top\" width=\"12.473572938689218%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cstrong\u003e\u003cem\u003eP\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e-value\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eAge\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e1.06\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.102639296187684%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(1.01\u0026ndash;1.12)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.4pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.944281524926685%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.017\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"13.782991202346041%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.651026392961876%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eFever\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.09\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.102639296187684%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.00\u0026ndash;0.86)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.4pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.944281524926685%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.034\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\n \u003cp style=\"margin: 0in 0in 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11px;\"\u003e0.001\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eSkin rash\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.02\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.102639296187684%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.0001\u0026ndash;0.38)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.4pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.944281524926685%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.007\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.01\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"13.782991202346041%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.00001\u0026ndash;0.22)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.651026392961876%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.002\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eVomiting/nausea\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.02\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.6pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"15.102639296187684%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.002\u0026ndash;0.11)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.4pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.944281524926685%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.001\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.8pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"13.782991202346041%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.0000001\u0026ndash;0.08)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.2pt;padding: 0in 5.4pt;height: 14.5pt;vertical-align: top;\" valign=\"top\" width=\"8.651026392961876%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eBleeding\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.01\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.6pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"15.102639296187684%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(0.0001\u0026ndash;0.21)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.4pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"8.944281524926685%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.002\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.8pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"13.782991202346041%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.2pt;padding: 0in 5.4pt;height: 12.45pt;vertical-align: top;\" valign=\"top\" width=\"8.651026392961876%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003ePlatelet count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.6pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"15.102639296187684%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.4pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"8.944281524926685%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 21pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"4.105571847507331%\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cbr\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/td\u003e\n \u003ctd style=\"width: 48pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e1.04\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.8pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"13.782991202346041%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(1.01\u0026ndash;1.09)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.2pt;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"8.651026392961876%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e0.001\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 157pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"30.64516129032258%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003eLymphocyte count, x 10\u003csup\u003e9\u003c/sup\u003e/L\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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16pt;vertical-align: top;\" valign=\"top\" width=\"9.3841642228739%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e213.28\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.8pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"13.782991202346041%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e(9.65\u0026ndash;98,867.53)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.2pt;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 16pt;vertical-align: top;\" valign=\"top\" width=\"8.651026392961876%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;line-height: normal;font-size:15px;font-family: Calibri, sans-serif;text-align: center;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u0026lt;0.0005\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;line-height: 29.333335876464844px;font-size:15px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 11px;\"\u003e\u003cspan style=\"line-height: 26.666664123535156px;\"\u003eaOR, adjusted odds ratio\u0026nbsp;shown as odds of having COVID-19\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003cspan style=\"font-size: 11px; line-height: 26.666664123535156px; font-family: Verdana, Geneva, sans-serif; color: rgb(0, 0, 0);\"\u003e, CI, confidence interval \u003c/span\u003e\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"COVID-19, influenza, dengue, Singapore, predictive models","lastPublishedDoi":"10.21203/rs.3.rs-36343/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-36343/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e The novel coronavirus disease 2019 (COVID-19) presents with non-specific clinical features. This may result in misdiagnosis or delayed diagnosis, and lead to further transmission in the community. We aimed to derive early predictors to differentiate COVID-19 from influenza and dengue.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eMethods: \u003c/strong\u003eThe study comprised 126 patients with COVID-19, 171 with influenza and 180 with dengue, who presented within 5 days of symptom onset. All cases were confirmed by reverse transcriptase polymerase chain reaction tests. We used logistic regression models to identify clinical characteristics and laboratory markers in classifying COVID-19 versus influenza, and COVID-19 versus dengue. The performance of the models were evaluated using receiver operating characteristic curves (ROC).\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eResults: \u003c/strong\u003eShortness of breath was the strongest predictor in the models for differentiating between COVID-19 and influenza, followed by diarrhoea. Higher lymphocyte count was predictive of COVID-19 versus influenza and versus dengue. In the model for differentiating between COVID-19 and dengue, patients with cough and higher platelet count were at increased odds of COVID-19, while headache, joint pain, skin rash and vomiting/nausea were indicative of dengue. The area under the ROC was 0.92 for flu model and 0.99 for dengue model.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eConclusion:\u003c/strong\u003e Models based on clinical features and simple laboratory markers for differentiating COVID-19 from influenza and dengue, which possess good predictive performance, can serve as a useful tool for primary care physicians to determine if further investigations or referrals would be required.\u003c/p\u003e","manuscriptTitle":"Differentiating coronavirus disease 2019 (COVID-19) from influenza and dengue","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2020-06-18 22:03:29","doi":"10.21203/rs.3.rs-36343/v1","editorialEvents":[{"type":"communityComments","content":1}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"78ad99d5-8fd5-4f94-9835-7dc07849997c","owner":[],"postedDate":"June 18th, 2020","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":123512,"name":"Infectious Diseases"}],"tags":[],"updatedAt":"2021-10-05T14:56:43+00:00","versionOfRecord":{"articleIdentity":"rs-36343","link":"https://doi.org/10.1038/s41598-021-99027-z","journal":{"identity":"scientific-reports","isVorOnly":false,"title":"Scientific Reports"},"publishedOn":"2021-10-05 14:56:43","publishedOnDateReadable":"October 5th, 2021"},"versionCreatedAt":"2020-06-18 22:03:29","video":"","vorDoi":"10.1038/s41598-021-99027-z","vorDoiUrl":"https://doi.org/10.1038/s41598-021-99027-z","workflowStages":[]},"version":"v1","identity":"rs-36343","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-36343","identity":"rs-36343","version":["v1"]},"buildId":"_2-kVJe1T_tPrBINL-cwx","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}