Study of Thermodynamic Properties of L-serine and L-threonine in Aqueous Solutions of 1- (2-carboxyethyl)-3-methylimidazolium chloride [HOOCEMIM][Cl]

Study of Thermodynamic Properties of L-serine and L-threonine in Aqueous Solutions of 1- (2-carboxyethyl)-3-methylimidazolium chloride [HOOCEMIM][Cl] | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Study of Thermodynamic Properties of L-serine and L-threonine in Aqueous Solutions of 1- (2-carboxyethyl)-3-methylimidazolium chloride [HOOCEMIM][Cl] Behnaz Asadzadeh, Roghayeh Majdan-Cegincara, Mohammed Taghi Zafarani-Moattar This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-1915213/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 20 Jan, 2023 Read the published version in Journal of Solution Chemistry → Version 1 posted 7 You are reading this latest preprint version Abstract The stability of amino acids in solutions containing electrolytes and the effect of ambient pH on their biological activity is one of the new research areas. In this research work, the volumetric and transport properties of ionic liquid (IL) aqueous solution with special performance of 1- (2-carboxyethyl) -3-methylimidazolium chloride ([HOOCEMIM][Cl]) were studied. The selected IL acts as an electrolyte with minimal toxicity and also allows the study of systems containing amino acids at acidic pH. In this work, the density, speed of sound and viscosity of binary and ternary solutions of IL in aqueous solution of amino acids in the structure of proteins, namely L-serine and L-threonine within IL molality range of (0.05, 0.07 and 0.09 mol kg -1 ) were measured at 298.15 K. From these quantities, apparent molar volume, limiting apparent molar volume, apparent molar isentropic compression, limiting apparent molar isentropic compression, transfer standard volumes for amino acids from water to the aqueous IL solutions and viscosity B -coefficients were calculated using the equations of Redlich–Meyer and Jones–Dole. Close examination of literature indicates that there is no data for water activity for solution of L-serine + H 2 O at 308.15 and 318.15 K. In this way water activity, osmotic coefficient and vapor pressure were measured and using the interaction parameters of Wilson, NRTL, NRF-NRTL and UNIQUAC models, activity coefficient values of L-serine calculated. Ionic liquid 1- (2-carboxyethyl) -3-methylimidazolium chloride L-serine Aqueous solutions Volumetric and transport properties Water activity Activity coefficient Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 20 Jan, 2023 Read the published version in Journal of Solution Chemistry → Version 1 posted Editorial decision: Major revision 05 Nov, 2022 Reviews received at journal 10 Oct, 2022 Reviewers agreed at journal 20 Sep, 2022 Reviewers invited by journal 25 Aug, 2022 Editor assigned by journal 01 Aug, 2022 Submission checks completed at journal 01 Aug, 2022 First submitted to journal 31 Jul, 2022 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-1915213","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":125554155,"identity":"5a75bc63-e144-48da-aef4-2ad4de1ee2a3","order_by":0,"name":"Behnaz Asadzadeh","email":"data:image/png;base64,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","orcid":"","institution":"Aalto University","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Behnaz","middleName":"","lastName":"Asadzadeh","suffix":""},{"id":125554157,"identity":"411cbf7d-f3f2-444a-889b-1174823e6e23","order_by":1,"name":"Roghayeh Majdan-Cegincara","email":"","orcid":"","institution":"Islamic Azad University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Roghayeh","middleName":"","lastName":"Majdan-Cegincara","suffix":""},{"id":125554160,"identity":"d8493fcb-2eeb-4e53-85c4-c6bc469b06c1","order_by":2,"name":"Mohammed Taghi Zafarani-Moattar","email":"","orcid":"","institution":"University of Tabriz","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Mohammed","middleName":"Taghi","lastName":"Zafarani-Moattar","suffix":""}],"badges":[],"createdAt":"2022-07-31 19:14:15","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-1915213/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-1915213/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1007/s10953-022-01235-2","type":"published","date":"2023-01-20T18:25:48+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":24795323,"identity":"cc1ed70d-389b-4b51-9b34-a667d01ca636","added_by":"auto","created_at":"2022-08-04 17:22:20","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":508801,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript1.pdf","url":"https://assets-eu.researchsquare.com/files/rs-1915213/v1_covered.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Study of Thermodynamic Properties of L-serine and L-threonine in Aqueous Solutions of 1- (2-carboxyethyl)-3-methylimidazolium chloride [HOOCEMIM][Cl]","fulltext":[{"header":"Full Text","content":"This preprint is available for \u003ca href='/article/rs-1915213/latest.pdf' target='_blank'\u003edownload as a PDF\u003c/a\u003e."}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"journal-of-solution-chemistry","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"josl","sideBox":"Learn more about [Journal of Solution Chemistry](http://link.springer.com/journal/10953)","snPcode":"10953","submissionUrl":"https://submission.nature.com/new-submission/10953/3","title":"Journal of Solution Chemistry","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false},"keywords":"Ionic liquid, 1- (2-carboxyethyl) -3-methylimidazolium chloride, L-serine, Aqueous solutions, Volumetric and transport properties, Water activity, Activity coefficient ","lastPublishedDoi":"10.21203/rs.3.rs-1915213/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-1915213/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThe stability of amino acids in solutions containing electrolytes and the effect of ambient pH on their biological activity is one of the new research areas. In this research work, the volumetric and transport properties of ionic liquid (IL) aqueous solution with special performance of 1- (2-carboxyethyl) -3-methylimidazolium chloride ([HOOCEMIM][Cl]) were studied. The selected IL acts as an electrolyte with minimal toxicity and also allows the study of systems containing amino acids at acidic pH. In this work, the density, speed of sound and viscosity of binary and ternary solutions of IL in aqueous solution of amino acids in the structure of proteins, namely L-serine and L-threonine within IL molality range of (0.05, 0.07 and 0.09 mol kg\u003csup\u003e-1\u003c/sup\u003e) were measured at 298.15 K. 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