Comparative Analysis of Vertebral Body and Local Infiltration Anesthesia in PVP Procedures

Abstract Background This study evaluates the effectiveness of local infiltration anesthesia and vertebral cancellous bone infiltration anesthesia in providing pain relief during vertebroplasty. Methods Between 2022 and 2024, This study involved 100 patients with osteoporotic vertebral compression fractures, randomly divided into two groups: Group A (local infiltration anesthesia) and Group B (local infiltration combined with vertebral cancellous bone infiltration anesthesia). Pain was assessed using the Visual Analog Scale, mean arterial pressure, heart rate, and blood oxygen saturation at preoperative, intraoperative, and 2-hour postoperative stages. Results No significant differences were observed between the two groups preoperatively in HR, MAP, or VAS scores (P > 0.05). Intraoperatively, Group B demonstrated significantly lower HR and MAP compared to Group A (P < 0.01). Furthermore, Group B exhibited superior pain control, with lower VAS scores during surgery (P < 0.01). Postoperative HR and MAP remained lower in Group B, but no significant differences in VAS scores were noted between the groups (P > 0.05). Providing confidence intervals alongside P-values offers a clearer representation of statistical precision. Conclusion Vertebral cancellous bone infiltration anesthesia may reduce the risk of cardiovascular events and provide better pain management during vertebroplasty than local infiltration anesthesia. The superior intraoperative analgesic effects make vertebral cancellous bone infiltration anesthesia a valuable option in clinical practice.