[Retroperitoneal endometriosis : When a rare form of endometriosis becomes a urological disease].

R H Waegner, Marianne Schmid, M Schmid, L Trojan, Lutz Trojan, S A Ahyai, Sascha Ahyai
Der Urologe. Ausg. A · 2016 · vol. 55(6) , pp. 756–62 · doi:10.1007/s00120-016-0119-0 · PMID:27294488 · W2464522639
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Retroperitoneal endometriosis, a benign condition affecting the ureters and bladder, requires an interdisciplinary approach with surgical excision as the gold standard therapy for symptomatic involvement.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

The paper discusses retroperitoneal endometriosis from a urological perspective, describing its symptoms and proposed pathogenesis and providing an overview of diagnosis and current guideline-based therapy options. It summarizes that ureteral and urinary bladder involvement can occur, with ureter involvement causing hydronephrosis representing an absolute indication for therapy, and recurrent macrohematuria from bladder involvement potentially requiring treatment. The authors state that surgical excision of clinically significant endometriosis foci is the first-line “gold standard,” with minimally invasive approaches preferred when feasible and medication considered secondary. This paper is centrally about endometriosis — specifically retroperitoneal endometriosis involving the ureters and bladder.

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Abstract

BACKGROUND: Retroperitoneal endometriosis is a common benign disease, which requires an interdisciplinary approach. In the clinical practice diagnosis is often delayed for years after onset of the unspecific symptoms so that increased awareness is necessary for detection of the presence of the disease. OBJECTIVE: This article provides a description of the disease including the symptoms and pathogenesis, an introduction to the complexity of diagnostic investigations and the current therapy recommendations. MATERIAL AND METHODS: Comparison of current therapy recommendations according to the guidelines under consideration of individual studies and background research. Assessment of studies and the accompanying interpretations with the intention of presenting an introduction to the topic with therapy recommendations. RESULTS: From a urological point of view retroperitoneal endometriosis is a benign disease affecting the ureters and urinary bladder. Involvement of the ureters leading to hydronephrosis caused by ureteral compression represents an absolute indication for therapy. Recurrent macrohematuria can also necessitate treatment. Treatment includes surgical excision of the focal point of endometriosis as the first line therapy. Various operative procedures and access routes are available but when possible a minimally invasive procedure should be used. A second line drug therapy is also possible. CONCLUSION: Surgical excision of a clinically significant focus of endometriosis is the gold standard for therapy. This procedure should take place in a specialized center within an interdisciplinary consensus. Due to the fact that endometriosis is primarily a benign disease, medical clarification for the patient concerning the benefits and risks of therapy is absolutely necessary. An individual therapy concept under consideration of factors, such as the specific clinical relevance and psychological stress is recommended and in close cooperation with the patient.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Retroperitoneal Space Urologic Diseases Urologic Diseases Diagnosis, Differential Endometriosis Endometriosis Endometriosis Evidence-Based Medicine Female Humans Retroperitoneal Space Treatment Outcome Urologic Diseases Urologic Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (31)

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