A Multicenter Study of the Correlations of Anterior and Posterior Corneal Parameters in Chinese Myopic Patients

In this observational cross-sectional study consisting of 8365 Chinese myopic patients from five different ophthalmic centers, we investigated the correlations between anterior and posterior corneal parameters. Strongly negative anterior-posterior correlations of the mean corneal curvature were observed, with similar correlation coefficients in all myopic groups ( R -0.85 to -0.88). The anterior-posterior correlations of corneal astigmatism ( R 0.65 to 0.75), eccentricity ( R 0.27 to 0.38) and asphericity ( R 0.29 to 0.41) were all positive, with slightly different correlation coefficients between the myopic groups. The anterior-posterior correlations of mean corneal curvature were strongly negative with similar correlation coefficients in all quantile groups of six corneal and anterior chamber parameters ( R -0.84 to -0.91), except Sim Km ( R -0.36 to -0.64). The anterior-posterior correlations of corneal astigmatism were all positive with slightly different correlation coefficients between the quantile groups of SimKm ( R 0.66 to 0.74). The anterior-posterior correlations of corneal eccentricity ( R 0.30 to 0.44) and asphericity ( R 0.33 to 0.45) were positive and slightly different between the quantile groups of SimKm, pachy apex and corneal volume. In conclusion, anterior-posterior correlations of corneal curvature, astigmatism, eccentricity and asphericity can be affected by the severity of myopia and some other corneal parameters.