The incidence and Risk Factors of fetuses with mirror-image dextrocardia with solitus inversus

Objective: This research seeks to ascertain the prevalence and determinants of mirror-image dextrocardia in fetuses Study Design: With December of 2022 as the reference point , we compiled colleted data on pregnant women who carried fetuses with mirror-image dextrocardia in Xi'an, Shaanxi Province: September-October 2022, November 2022, and December 2022-January 2023 An online questionnaire was distributed to 209 pregnant across china who had contracted COVID-19. The case group comprised women whose final menstrual cycle occurred in November 2022 and who had a fetus with mirror-image dextrocardia. Women with a November 2022 final menstrual period and a fetus without this condition made up the control group. To identify the risk factors associated with fetal mirror-image dextrocardia, both univariate and multivariate logistic regression analyses were employed. Results: : A significant difference was noted in the gestational age at COVID-19 infection women with a September to October 2022 and December 2022 to January 2023 final menstrual period who did not bear a fetus with mirror-image dextrocardia, and those with a November 2022 final menstrual period whose fetus exhibited this condition. The univariate and multivariate analyses conducted on pregnant women with a final menstrual period in November 2022 who had contracted COVID-19 revealed significant differences in the presence and duration of fever between those bearing fetuses with mirror-image dextrocardia and those without (P = 0.000). Conclusion: The findings suggest two critical factors to the increased prevalence of fetal mirror-image dextrocardia : 1) the infection timing which occurs between the 4th and 6th week of pregnancy; 2) the presence of fever and its prolonged duration.