Effect of drug therapy on pregnancy rate, sex hormone levels and adverse reactions after laparoscopic surgery in patients with endometriosis and infertility

Sun XY, Xuri Sun, X Y Sun, Liang Z, Z Liang
Journal of biological regulators and homeostatic agents · 2021 · vol. 35(1) , pp. 191–196 · doi:10.23812/20-458-l · PMID:33478207 · W3123115179
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⚙ AI-generated summary by gemini-2.5-flash-lite+body, 2026-08-03 ⓘ

This study evaluated the effects of gestrinone, mifepristone, and triptorelin acetate drug therapies on pregnancy rates, sex hormone levels, and adverse reactions in infertile patients with endometriosis after laparoscopic surgery.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-14 · read from full text ⓘ

This study investigated the efficacy of postoperative drug therapy in improving pregnancy rates and modulating sex hormone levels among patients with endometriosis-related infertility who underwent laparoscopic surgery. The research compared outcomes across different pharmacological interventions, including gestrinone, mifepristone, and triptorelin acetate, while also monitoring for adverse reactions associated with each treatment regimen. Key findings indicated that specific hormonal suppressants significantly influenced reproductive outcomes and biochemical markers following surgical intervention for the condition. This paper is centrally about endometriosis — specifically evaluating adjuvant medical therapies to enhance fertility after surgical management of the disease.

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Keywords

endometriosis;gestrinone;mifepristone;sex hormone levels;triptorelin acetate

References

Supporting Agencies Copyright (c) 2021 XY Sun, Z Liang This site is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). Editor-in-Chief Medical Genetics, University of Torino Medical School, Italy Co-Editor-in-Chief Department of Biomedical, Surgical and Dental Sciences, University of Milan, Italy Indexing & Archiving News & Announcements 2026-02-09 Journal of Biological Regulators and Homeostatic Agents (JBRHA, Print ISSN: 0393-974X, Electronic ISSN: 1724-6083) has officially transitioned to China Scientific Research Publishing, taking over publication from Asia Pacific Academy of Science Pte. Ltd. with effect from Vol 40, No 1 (2026). All new submissions should be made via the new journal website at https://journal.csrp-pub.com/index.php/jbrha from February 10, 2026. For any inquiries regarding this transition and the publication of manuscripts being processed, please contact the new publisher at [email protected] or [email protected]. 2025-02-01 In addition to the first issue that has already been published by the original publisher, there will be four more issues released this year, with scheduled publication dates in March, June, September, and December respectively. 2025-01-21 Starting from Volume 39 Issue 2 (2025), the ownership of Journal of Biological Regulators and Homeostatic Agents (ISSN: 0393-974X (P); 1724-6083 (O)) will be transferred from Biolife Sas to Asia Pacific Academy of Science Pte. Ltd. As of 21 January 2025, authors should make submissions to the new journal system and follow the author guidelines. Asia Pacific Academy of Science Pte. Ltd. will take over the publication of manuscripts being processed.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Endometriosis Endometriosis Infertility, Female Laparoscopy Female Gonadal Steroid Hormones Humans Pregnancy Pregnancy Rate

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