Mapping and characterizing endometrial implants by registering 2D transvaginal ultrasound to 3D pelvic magnetic resonance images.

Yavariabdi A, Adrien Bartoli, Samir C, Artigues M, Michel Canis
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2015 · doi:10.1016/j.compmedimag.2015.07.007 · PMID:26241161
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Abstract

We propose a new deformable slice-to-volume registration method to register a 2D Transvaginal Ultrasound (TVUS) to a 3D Magnetic Resonance (MR) volume. Our main goal is to find a cross-section of the MR volume such that the endometrial implants and their depth of infiltration can be mapped from TVUS to MR. The proposed TVUS-MR registration method uses contour to surface correspondences through a novel variational one-step deformable Iterative Closest Point (ICP) method. Specifically, we find a smooth deformation field while establishing point correspondences automatically. We demonstrate the accuracy of the proposed method by quantitative and qualitative tests on both semi-synthetic and clinical data. To generate semi-synthetic data sets, 3D surfaces are deformed with 4-40% degrees of deformation and then various intersection curves are obtained at 0-20° cutting angles. Results show an average mean square error of 5.7934±0.4615mm, average Hausdorff distance of 2.493±0.14mm, and average Dice similarity coefficient of 0.9750±0.0030.
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