Clinical course and characteristics of patients with 2019 novel coronavirus disease in Wuhan, China: a single-centered, retrospective, observational study

Background: COVID-19 associated with SARS-CoV-2 infection is of outbreak worldwide. This project aimed to provide clinical features, treatment advice and risk factors of patients diagnosed with COVID-19.MethodsIn this study, we analyzed 109 patients with confirmed COVID-19. We compared the relevant data of patients over 60 years old and under 60 years old, analyzed the data of patients with chronic diseases, and clarified the importance of the combination of laboratory examination and CT diagnosis.ResultsMost of patients 59(54.1%) had no fever. 100(91.7%) of patients required supplemental O 2 , and their SpO2 values reached normal after oxygen therapy. 72 (66.1%) patients were over 60 years old, and they were more likely to develop respiratory symptoms. Among all patients, only 14 (12.8%) patients were positive for anti-SARS-CoV-2 antibody, SARS-COV-2 RT-PCR assay and CT diagnosis.Conclusion(1) O 2 supplement therapy plays an important role in the treatment of COVID-19 patients.(2) People over 60 years old or(and) having chronic diseases are risk factors of SARS-CoV-2 infection.(3) Most patients infected with SARS-CoV-2 have no fever symptoms.(4) We recommend that CT positive results be included in the confirmed diagnosis criteria, which is important for the diagnosis of COVID-19.