Hematological profile derangement in newborns as an outcome of hypertensive disorders of pregnancy.

Abstract Objectives This study aimed at determining the changes of hematological parameters in newborns of mothers with HDP compared to normotensive mothers.Results This was a hospital-based comparative cross-sectional study conducted from December 2017 to May 2018. The study groups consisted of 70 normotensives and 73 hypertensive pregnant women as a comparison and index group respectively. The male to female ratio for the newborns was 1:1. Newborns of the hypertensive mothers had a lower birth weight, lower APGAR score and had a lower median gestation age at the time of birth compared to the newborns of normotensive mothers (P < 0001). White blood cell and differential counts were lower in cord blood of the newborns of HDP group than in the normotensive group (P≤0.001). Approximately 50% of newborns of hypertensive mothers had thrombocytopenia. Furthermore, hypertensive disorders of pregnancy were found to independently predict neutropenia [OR=6 (2.1 – 19.4), p<0.05] and thrombocytopenia [OR=4.3(1.7 – 11.1), p<0.001] in the newborns.