Uro-colon CT in the diagnosis of pelvic deep infiltrating endometriosis. .

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Uro-colon CT with a dose-reduction protocol showed high diagnostic accuracy for deep infiltrating endometriosis involving the digestive tract and bladder, aiding presurgical planning.

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Abstract

Purpose: To evaluate the diagnostic accuracy (DA) of the uro-colon-CT (UCCT) with dose-reduction dedicated protocol in preoperative study of deep infiltrating endometriosis of the anterior and posterior compartments (aDIE and/or pDIE). \nMethods and Materials: 73 patients with clinical suspicion of aDIE and/or pDIE were analysed retrospectively, undergone U-CCT between January 2012 and December 2014 before laparoscopic surgery, and imaging data were compared with the surgical and histological reports. We calculated sensitivity, specificity, PPV, NPV of U-CCT and evaluated the utility of this technique to select patients who need a more detailed presurgical planning. \nResults: 74 surgical interventions were performed on 73 patients (one patient was exposed to surgery twice due to DIE relapse after two years). In 4/74 surgical interventions U-CCT with dose-reduction dedicated protocol was negative for DIE. The urologists were properly involved when DIE nodules concerning ureters and bladder (p=0,042); The colorectal surgeons were more often involved when DIE nodules concerning sigmoid colon, particularly in case of bowel stenosis >50% (p=0,031%). U-CCT attested better results in the evaluation of DIE nodules involving digestive tract (DA 81%; p=0,000) and bladder (DA 87,8%; p=0,000). \nConclusion: U-CCT with dose-reduction dedicated protocol proved to be a valid alternative to barium-enema x-ray and urography or in absence of MRI with targeted protocol, to elaborate a detailed presurgical planning in selected patients with DIE; in particular this method is very helpful to individuate DIE nodules involving digestive tract or bladder and to evaluate the correct involvement of the urologist and/or the colorectal surgeon.
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Keywords

Urinary Tract / Bladder, Colon, Genital / Reproductive system female, CT, Colonography CT, Dosimetric comparison Authors: S. Zanardi, F. Coppola, D. Papadopoulos, D. Valerio, A. O. Di Vincenzo, L. Zannoni, R. Seracchioli, R. Golfieri; Bologna/IT DOI: 10.1594/ecr2017/B-1099 Purpose To evaluate the diagnostic accuracy (DA) of CT-colonography with intravenous contrast medium and urographic phase (U-CTC) in the preoperative evaluation of pelvic deep infiltrating endometriosis (DIE) with intestinal and/or urinary tract localizations.

Methods

and materials We retrospectively analyzed the 186 consecutive patients that underwent an U-CTC examination for strong clinical suspicion of intestinal and/or urinary tract DIE. U-CTC is a low-dose CT colonography with a dedicated protocol with fasting for six hours before the examinations, then 10 minutes before the U-CTC an intramuscular injection of 20 mg of hyoscine-N-butylbromide was administered (in absence of contraindications) to reduce bowel peristalsis. The distention of the colon was obtained by introducing 1.5-2 L of air or CO2 in the rectum through a 24...

Results

Fifty-five patients (75.3%) had lesions involving the GI tract at U-CTC (18 of them required the involvement of the general surgeon, 32.7%) while 46 patients (63.0%) had lesions involving the urinary tract and 31 of them (67.4%) required the involvement of an urologist. Thirty-six of these patients showed lesions in both compartments (49.3%). The diagnostic performance of U-CTC for the diagnosis of DIE according to the different anatomical localizations is shown in Table 1. As far as the intestinal lesions were concerned, U-CTC demonstrated sensitivity...

Conclusion

In our experience U-CTC is not routinely adopted for the diagnosis of endometriosis, usually achieved with TVS or MRI, but it is performed only before surgery, in selected patients with strong clinical suspicion of DIE nodules that result to be more difficult to detect with TVS and standard MRI, like localizations involving the sigmoid colon, the recto-sigmoid junction, the ureters and the bladder dome. The limitations of this technique is the radiation exposure in young females, even if a dose reduction protocol was utilized, but...

References

1.Chapron C,Fauconnier A, Dubuisson JB, Barakat H, Vieira M, Breart G. Deep infiltrating endometriosis: relation between severity of dysmenorrhoea and extent of disease. Human Reproduction 2003; 18(4):760-766. 2. Roman H, Ness I, Suciu N, Bridoux V, Gourcerol G, Leroi AM et Al. Are digestive symptoms in women presenting with pelvic endometriosis specific to lesion localizations? A preliminary prospective study. Hum Reprod 2012; 27(12):3440-3449. 3. Moawad NS, Caplin A. Diagnosis, management, and long-term outcomes of rectovaginal endometriosis. Int J Womens Health 2013; 5:753-63 4. Ferrero S,...

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endometriosisdie_deep_infiltrating

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