Vol.:(0123456789)1 3
Archives of Gynecology and Obstetrics (2019) 299:287
https://doi.org/10.1007/s00404-018-4984-1
LETTER
Letter to the editor
Jacob Brink Laursen1 · Jeppe Bennekou Schroll1
Received: 16 August 2018 / Accepted: 17 November 2018 / Published online: 7 December 2018
© Springer-Verlag GmbH Germany, part of Springer Nature 2018
Dear Editor
Recently, we read the article “The effect of surgical man -
agement of endometrioma on the IVF/ICSI outcomes when
compared with no treatment? A systematic review and
metaanalysis” [1]. It was written by M. Nickkho-Amiry as
the lead author and published in your journal. We read it
with great interest. Together with my research group, I wrote
an article on the same topic, based on almost the same mate-
rial and it was published in Acta Obstetricia et Gynecologica
Scandinavica in spring 2017 [2].
In Fig. 2 (Forrest Plots examining outcome measures),
in the Forrest plot for “Live Birth Rate/cycle”, the axis
may have been named wrongly. A quick calculation shows
that number of events out of total events in the “Treated
Endometrioma”-group of the Bongioanni study equals
roughly 26% (29/112 = 0.258). The events out of total events
in the “Non Treated Endometrioma”-group of the same
study equals 35% (49/142 = 0.345). This must necessarily
mean that the result favors no surgery, since the percentage
of live birth rates per cycle is higher. This is in contrast to
what the plot shows, as this indicates that the result is in
favor of surgery (The square is on the “favors surgery”-side
of 1). The same appears to go for all the other studies and
actually also includes the Forrest plots of “Clinical Preg -
nancy/cycle” and “Pregnancy/Cycle”. Based on the results
of our own systematic review, it probably will not have any
effect on the final result and recommendations, but I hope
you will have the opportunity to look into the matter and
acquire a comment from the authors.
If it turns out that I have misinterpreted the figure, please
accept my apologies, and I will of course take any comment
from you or the authors into consideration.
Kind regards,
Jacob Brink Laursen, MD, Senior Registrar
Jeppe Schroll, MD
Author contributions JBL Manuscript writing/editing; JBS Manuscript
editing.
Compliance with ethical standards
Conflict of interest We declare we have no conflict of interest.
References
1. Nickkho-Amiry M, Savant R, Majumder K, Edi-O’sagie E, Akhtar
M (2018) The effect of surgical management of endometrioma
on the IVF/ICSI outcomes when compared with no treatment?
A systematic review and meta-analysis. Arch Gynecol Obstet
297(4):1043–1057. https ://doi.org/10.1007/s0040 4-017-4640-1
2. Brink Laursen J, Schroll JB, Macklon KT, Rudnicki M (2017)
Surgery versus conservative management of endometriomas in
subfertile women. A systematic review. Acta Obstet Gynecol
Scand 96:727–735
* Jacob Brink Laursen
[email protected]
1 Hvidovre Hospital, Copenhagen, Denmark
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