Nexplanon: the new implant for long-term contraception. A comprehensive descriptive review

Stefano Palomba, Angela Falbo, Annalisa Di Cello, Caterina Materazzo, Fulvio Zullo
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2012 · vol. 28(9) , pp. 710–721 · doi:10.3109/09513590.2011.652247 · PMID:22339096 · W2123564518
review OA: closed CC0 ⤵ 1 in-corpus citation
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This review analyzes published data on Nexplanon's contraceptive effectiveness, pharmacological properties, insertion/removal procedures, efficacy, safety, bleeding management, potential uses for endometriosis and PMS, and contraindications.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Nexplanon(®) is a new long-term reversible contraception method. The current review is aimed to analyze the published data concerning the contraceptive effectiveness of Nexplanon(®) and its effects on reproductive function. Pharmacological properties and technical procedures of insertion and removal, as well as the efficacy and safety data available, were discussed. Possible strategies for treating Nexplanon(®)-related bleeding were also described. With regard to the future research and the future scientific developments of contraceptive implants, the possible use of Nexplanon(®) wide-ranging for the symptomatic treatment of endometriosis and premenstrual syndrome (PMS) were considered. Finally, it was defined in which women the use of Nexplanon(®) is indicated and in which it is contra-indicated.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Contraception Contraceptive Agents, Female Desogestrel Contraception Contraceptive Agents, Female Desogestrel Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (78)

Cited by (1)

Source provenance

europepmc
last seen: 2026-06-21T06:12:49.409960+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:16:23.388809+00:00
unpaywall
last seen: 2026-06-21T16:06:39.831647+00:00
License: CC0 · commercial use OK