Multicompartment body composition analysis in older adults: a cross-sectional study

Multicompartment body composition analysis in older adults: a cross-sectional study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Multicompartment body composition analysis in older adults: a cross-sectional study Ana Claudia Rossini-Venturini, Lucas Veras, Pedro Pugliesi Abdalla, and 9 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-1835649/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 09 Feb, 2023 Read the published version in BMC Geriatrics → Version 1 posted 11 You are reading this latest preprint version Abstract Background: During aging, changes occur in the proportions of muscle, fat, and bone. The body composition (BC) alterations have a great impact on health, quality of life, and functional capacity. Several equations to predict BC using anthropometric measurements have been developed from a bi-compartmental (2-C) approach that determines only fat mass (FM) and fat-free mass (FFM). However, these models have several limitations, when considering constant density, progressive bone demineralization, and changes in the hydration of the FFM, as typical changes during senescence. Thus, the main purpose of this study was to propose and validate a new multi-compartmental anthropometric model to predict fat, bone, and musculature components in older adults of both sexes. Methods: This cross-sectional study included 100 older adults of both sexes. To determine the dependent variables (fat mass [FM], bone mineral content [BMC], and appendicular lean soft tissue [ALST]) whole total and regional DXA body scans were performed. Twenty-nine anthropometric measures and sex were appointed as independent variables. Models were developed through multivariate linear regression. Finally, the predicted residual error sum of squares (PRESS) statistic was used to measure the effectiveness of the predicted value for each dependent variable. Results: An equation was developed to simultaneously predict FM, BMC, and ALST from only four variables: weight, half arm span (HAS), triceps skinfold (TriSK), and sex. This model showed high coefficients of determination and low estimation errors (FM: R 2 adj : 0.83 and SEE: 3.16; BMC: R 2 adj : 0.61 and SEE: 0.30; ALST: R 2 adj : 0.85 and SEE: 1.65). Conclusion: The equations provide a reliable, practical, and low-cost instrument to monitor changes in body components during the aging process. The internal cross-validation method PRESS presented sufficient reliability in the model as an inexpensive alternative for clinical field use. aging DXA equation fat mass bone mineral content ALST Figures Figure 1 Background Muscle, fat, and bone are three main components of interest in the body composition (BC) field ( 1 ). Aging processe involve proportional changes in these components ( 1 ) due to decreased levels of anabolic steroids and sex hormones ( 2 ). These alterations in the older adults’ BC have a great impact on their health and quality of life, expose them to the risk of malnutrition, and could lead to conditions of disability ( 3 ). Skeletal muscle mass (SMM) has various essential physiological functions in humans and its maintenance is important to keep the body healthy, especially during aging. Thus, the reduction of SMM impairs muscle strength, and functional capacity, increasing the chances of morbidity and mortality ( 4 , 5 ). As result, diverse functional and metabolic disorders in older adults also can occur ( 6 , 7 ). As a large proportion of SMM (≅ 74%) is found in the extremities and the main proportion of appendicular lean soft tissue (ALST) is SMM (≅ 76%) ( 8 ). So, the ALST is a representative measure of the SMM. In addition, ALST is used to identify sarcopenia ( 9 ), sarcopenic obesity ( 10 ), osteosarcopenia ( 11 ), and osteosarcopenic obesity ( 2 ). In turn, the bone mineral content (BMC) presents important variations throughout the olders’ life. Peak BMC occurs in the third decade of life and declines over the years ( 12 ). This reduction is similar in men and women before 50 years of age, but after this, the differences become very distinct against women because of menopause ( 13 ). This skeletal reduction restrains bone strength and can cause osteopenia and osteoporosis. The World Health Organization defines osteopenia and osteoporosis as a T score equal to or less than − 1 and − 2.5 standard deviations, respectively; below the peak bone mass of a young healthy cohort ( 12 ). Osteoporosis increases the risk of fractures and is an important health problem faced by older adults ( 14 ). Meanwhile, fat mass (FM) presents an increase during aging ( 15 ). From the 70 years old, the FM increases (7.5%) in a similar way for both sexes ( 16 ), becoming one of the main risk factors for chronic diseases ( 17 ), some types of cancer ( 18 ), physical disability ( 19 ) and mortality ( 20 ). In this sense, changes in ALST, BMC, and FM during senescence have a great impact on their health ( 21 ), quality of life, and functional capacity ( 22 ). Follow-ups and interventional studies are desirable at this stage of life ( 23 ). To monitor this BC variability, simple and low-cost methods are required ( 23 ). Several equations to predict BC using anthropometric measurements have been developed to determine FM and fat-free mass (FFM). Body density (BD) is usually thereferential method for estimating body fat by hydrostatic weighing ( 24 – 28 ). However, these models have limitations regarding the estimation of older’s BD and BC ( 29 ). The traditional bi-compartmental (2-C) model is based on the assumption that there is a linear relationship between subcutaneous fat, total fat, and BD. However, the correlation between total and subcutaneous body fat decreases with age ( 30 , 31 ). Perhaps it is due to; 1) the redistribution of FM from the extremities to the visceral area, and 2) due to fat infiltration in the SMM. Thus, there is an overestimation of the BD, and consequently, the FM is underestimated ( 32 ). Another worrying limitation is to assume a constant density of 0.9007 g/cm 3 and 1.100 g/cm 3 for the FM ( 33 ) and FFM ( 34 ), respectively. However, the natural aging process causes a progressive bone demineralization ( 35 ) and changes in the hydration of the FFM, causing a decrease in its density ( 36 ) which also affects the FM estimate ( 35 , 36 ). Furthermore, these 2-C equations do not evaluate other components, such as ALST and BMC, fundamental components in vulnerable peoples ( 37 ) and older adults ( 38 ). Moreover, the ALST is a consensual parameter for SMM among agencies. It is equivalent to muscle tissue in arms and legs, except for a small amount of connective tissue and skin ( 39 ). Since the methodological advances are necessary to analyze the BC in a more precise and detailed way, providing a broader understanding of the metabolic functions of each component ( 40 ). Among imaging analysis methods, dual energy X-ray absorptiometry (DXA) is widely used because its offers advantages such as low cost, speed of measurement (whole-body scans need less than 20 min), noninvasive, efficiency in the simultaneous determination of several components in a single scan ( 41 ), and their radiation exposure are considered small and safe for repeated measures (< 1 mrem for whole-body scans) ( 42 ). Furthermore, DXA is considered a 3-C model ( 43 , 44 ), once it can accurately measure FM, BMC, and appendicular lean soft tissue (ALST) ( 45 ). ALST is mainly muscle (≅ 76%) ( 46 , 47 ) and a large proportion (≅ 74%) of SMM is in the extremities ( 8 ). Thus, ALST is the strongest predictor of SMM ( 8 ) and is widely used in sarcopenia consensus ( 9 , 48 ). However, BC assessment with sophisticated equipment such as DXA is restricted to specific professionals, requiring a specialized structure. Then, why anthropometric measurements are simple and with a low cost associated ( 49 ), their use has been presented as valid alternatives for estimating BC in a multicompartmental approach in children and adolescents of both sexes ( 50 , 51 ), sarcopenia risks ( 39 , 52 ) lipodystrophy of seropositive patients ( 37 , 53 ) and muscle loses in older adults ( 54 ). Accordingly, this proposal may also be viable for older adults, as long as it is a practical, simple and non-invasive tool. So, the objective of this study was to propose and validate a multi-compartmental anthropometric model for the prediction of fat, bone, and musculature components in older adults of both sexes. Our hypothesis is that body composition can be estimated through anthropometric measurements. Methods Design and Study population In this study, we adopted a cross-sectional design to develop and validate a multicomponent anthropometric model to simultaneously estimate LST, BMC, and FM. The study was conducted from October 2016 to May 2017. The study sample was derived from physically independent community-dwelling older adults in a city in southeastern Brazil. The inclusion criteria were: adults aged 60–85 years, of both sexes, who walk independently. The exclusion criteria were: the presence of diseases that restrict mobility or muscle strength; absence of unstable cardiovascular condition; acute infection; tumor; back pain; prostheses, individuals with a diagnosis of cancer or uncontrolled diseases, who presented sequel of stroke, experienced a weight loss more than three kilograms (kg) in the last 3 months, had a cognitive limitation that restricts understanding and taking tests, who did not complete all the stages or desired to withdraw from the study. The study was approved by the Ethical Review Board of Hospital das Clinicas at the Medical School of the University of Sao Paulo (HC-FMRP/USP), following the ethical guidelines outlined in the 1975 Helsinki Declaration. Written informed consents were obtained from all individuals included in the study, after a brief explanation of the study objectives and evaluations. This manuscript followed the guidelines from The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) conference list, and the completed checklist is attached. The sample size calculation was considered the desired maximum error (ε) and degree of confidence (Zy), previously knowing the population variability (σ 2 ) ( 55 ). For this, we used the variable with the greatest variability (FM; SD = 8.7 kg) expected for such a population ( 56 ). Once the predetermined error estimate (ε ≤ 1.8 kg) and maximum desired error (5%) the ideal n for the study ( 55 ) was defined (n = 90). Study protocol A multidisciplinary health-trained team (nurses, nutritionists, pharmacists, physical education professors, physicians, and physiotherapists) performed data collection. All procedures, for each participant, were completed during one visit to the laboratories at the Hospital das Clinicas at the Medical School of the University of Sao Paulo at Ribeirao Preto (HCFMRP/USP). Participants came to the laboratory after an overnight fast (8h fast), abstaining from vigorous exercises, and no caffeine and alcohol during the preceding 24h. Before the measurements, the subjects were asked to empty their bladders. A total-body DXA scan was executed according to the manufacturer's guidelines. The anthropometric measures were taken according to the literature guidelines ( 57 ), whose procedures are summarized below. The dependent variables Whole and regional body composition were determined by DXA (Hologic® scanner, model QDR4500W; version 11.2, Bedford, MA). The DXA measurements included absolute values of appendicular lean soft tissue (ALST, kg), bone mineral content (BMC, kg), and fat mass (FM, kg), considered dependent variables. As the BMC represents the gray portion of bone, the bone adjustment was performed by multiplying the BMC by 1.0436 ( 58 ). The ALST was obtained through the sum of the lean soft tissue (LST) of the lower and upper limbs on both sides ( 59 ). The DXA measurements were electronically transferred to an external HD and organized into a general data sheet without manual typing. The independent variables The participant’s body mass and height were measured with a digital scale (Filizola® (model Personal, Campo Grande , MS) and a hall fixed stadiometer (Sanny® Professional – ES2020), respectively. The skinfolds (n = 09) were measured with Lange caliper with precision in mm, on the right side of the body in the regions. The circumferences (n = 08) were realized using inelastic and inextensible tape (Sanny®). The widths (n = 08) were measured with Pachymeter (Sanny®). In addition, knee height and half arm span (HAS) were measured using a Sanny® segmometer. All these procedures followed conventional standardization ( 60 ). The anthropometric measurements of our laboratory remain within the limits of reliability ( 51 ). Statistical analysis The basic analysis involved descriptive statistics using measures of central tendency to describe the characteristics of the sample. To verify the data normality, the Shapiro–Wilk test was applied. Comparisons between sex were performed using Student’s t-test for independent samples. For the Multicompartmental anthropometric equation development, we adopted previous procedures ( 50 , 51 ), briefly described below. Through the determination of 30 independent variables plus the sex for the prediction of the 3 dependent variables, the multivariate regression model (nYm = nX(r + 1) (r + 1) βm + nεm) by diagonal mutual analysis, parameter estimation, and the least squares errors method was used ( 61 ) by R Statistical Software (version 4.1.2, R Foundation for Statistical Computing, Vienna, Austria). The criteria for selection and reduction of independent variables followed the following steps: a) factor analysis and model adequacy (Kaiser-Meyer-Olkin) and Sphericity test (Bartlett) were performed to verify the suitability of the sample; b) univariate linear regression to determine all common independent variables for each dependent variable (ALST, BMC, and FM), with significantly less than 5%; c) multivariate linear regression to estimate the parameters and Pillai approximation method for showing possible variables exclusions; d) testing of the remaining model (enter - univariate method), with estimated values of VIF (< 10.0) and multicollinearity (L < 1000) maximum permitted; e) adjustments by Pillai approach to testing the F values; f) as the variable sex is a categorical variable, it could not enter in the factor analysis. However, it will be added to the multivariate model due to its theoretical relevance and assumption of improving the model; g) then multivariate β parameters were determined, with the proposition of equations and residual distribution for each dependent variable; h) Akaike information criterion (AIC) statistic to ensure greater quality and simplicity of the statistical model. The details of the statistical procedures have been previously described in adolescents of both sexes ( 50 , 51 ). Finally, the predicted residual error sum of squares (PRESS) statistic was used to measure the effectiveness of the predicted equations for each dependent variable. The procedure may be understood as design efficiency in estimating the actual parameters by a virtual simulation that is, from the exclusion of an observation, equations are proposed with the remaining sample and replicated through cross-validation for each participant that was excluded. For validation, we follow the following steps: a) the correlation coefficients were estimated between predicted and measured values and b) cross-validation by PRESS method, coefficients of determination (Q 2 PRESS ), and error (S PRESS ) for each dependent variable (ALST, BMC, and FM) ( 61 ). Results Table 1 shows anthropometric and body composition measures of the eligible participants. The means of all variables are within the confidence interval (95% CI), within the range limits for normal trends of distribution. Men were statistically taller, heavier, larger, and longer in most comparisons with women. Also had higher values of ALST, BMC, and residual mass. On other hand, women presented higher skinfolds, fat mass, and circumferences of hip and thigh values ( p < 0.05). Table 1 – Descriptive values of anthropometric and body composition variables in older adults, difference test by sex. Men (n = 31) Women (n = 69) Mean (SD) 95% CI Variance Min - Max Mean (SD) 95% CI Variance Min - Max p IL UL IL UL Age (years) 72 (7.6) 69.2 74.8 57.8 60.0–88.0 69.8 (5.9) 68.4 71.3 35.4 60.0–85.0 0.133 Anthropometric variables Height (cm) 168.0 (8.0) 165.0 170.9 64.0 150.5–188.0 156.2 (6.0) 154.8 157.6 35.4 145.0–174.0 < 0.001 Weight (kg) 71.7 (13.3) 66.9 76.6 177.8 42.0–108.0 65.8 (11.4) 63.0 68.5 130.9 39.0–102.0 0.022 Knee height (cm) 53.6 (2.6) 52.6 54.5 7.0 49.1–61.8 49.6 (2.1) 49.1 50.1 4.5 45.0–54.4 < 0.001 Half arm span (cm) 87.4 (4.7) 85.6 89.1 21.8 78.7–101.0 80.9 (3.7) 79.9 81.8 13.9 69.1–89.5 < 0.001 Skinfold Subscapular skinfold (mm) 23.2 (8.5) 20.0 26.3 72.3 6.0–37.0 28.3 (8.8) 26.2 30.4 77.0 8.0–47.0 0.007 Triceps skinfold (mm) 15.1 (5.8) 13.0 17.3 34.0 4.0–26.0 25.8 (6.9) 24.2 27.5 48.0 9.0–46.0 < 0.001 Biceps skinfold (mm) 8.1 (3.5) 6.8 9.4 12.2 3.0–15.0 15.2 (5.3) 13.9 16.5 28.6 5.0–34.0 < 0.001 Media axillary skinfold (mm) 18.5 (7.6) 15.8 21.3 57.4 4.0–30.0 23.7 (6.8) 22.1 25.4 46.5 5.0–41.0 0.001 Pectoral skinfold (mm) 16.9 (5.4) 15.0 18.9 28.9 4.0–26.0 14.7 (6.4) 13.2 16.2 40.5 4.0–40.0 0.094 Suprailiac skinfold (mm) 19.7 (9.8) 16.1 23.3 95.5 5.0–39.0 29.3 (7.9) 27.4 31.2 63.0 8.0–50.0 < 0.001 Vertical abdominal skinfold (mm) 25.9 (8.3) 22.8 28.9 68.5 5.0–39.0 33.6 (8.6) 31.6 35.7 74.5 6.0–55.0 < 0.001 Media Thigh skinfold (mm) 18.1 (7.5) 15.4 20.9 56.0 5.0–40.0 32.2 (11) 29.6 34.8 120.1 9.0–65.0 < 0.001 Calf skinfold (mm) 11.9 (6.4) 9.5 14.3 41.4 2.0–34.0 23.8 (7.4) 22.0 25.6 55.2 6.0–45.0 < 0.001 Circumference Chest circumference (cm) 97.8 (9.2) 94.4 101.1 84.5 82.0–116.5 92.9 (7.6) 91.1 94.8 58.2 72.0–115.5 0.007 Arm circumference (cm) 28.8 (3.5) 27.6 30.1 12.0 20.0–36.0 29.9 (3.8) 29.0 30.8 14.1 22.0–40.8 0.178 Forearm circumference (cm) 26.0 (2.0) 25.2 26.7 3.8 20.0–30.0 23.8 (2.3) 23.3 24.4 5.1 19.0–30.0 < 0.001 Waist circumference (cm) 92.2 (11.1) 88.1 96.2 122.8 68.5–115.0 86.2 (10.0) 83.8 88.6 100.6 65.0–113.0 0.009 Abdominal circumference (cm) 96.1 (10.9) 92.1 100.1 118.5 68.0–115.5 95.4 (10.9) 92.8 98.0 119.7 70.0–120.0 0.766 Hip circumference (cm) 96.8 (6.6) 94.4 99.2 43.1 80.0–111.5 100.6 (9.0) 98.5 102.8 81.7 81.5–128.0 0.038 Medial thigh circumference (cm) 47.1 (5.6) 45.1 49.2 31.7 32.0–57.0 52.8 (6.3) 51.3 54.3 40.3 37.5–69.0 < 0.001 Calf circumference (cm) 35.6 (3.5) 34.3 36.9 12.1 26.5–42.5 34.9 (3.0) 34.2 35.6 8.7 25.2–42.0 0.268 Girth Bi-acromial breadth (cm) 39.9 (2.7) 38.9 40.9 7.1 33.6–44.1 37 (2.0) 36.6 37.5 4.1 32.9–45.0 < 0.001 Bi-iliac breadth (cm) 31.3 (2.6) 30.3 32.3 6.9 28.1–39.8 30.8 (2.1) 30.2 31.3 4.3 26.2–37.0 0.268 Bi-trochanteric breadth (cm) 33.8 (1.7) 33.2 34.5 2.9 31.4–39.7 33.3 (2.3) 32.8 33.9 5.2 28.7–39.9 0.289 Bi-maleolar breadth (cm) 7.0 (0.5) 6.8 7.2 0.3 6.0–8.2 6.3 (0.4) 6.2 6.4 0.1 5.4–7.4 < 0.001 Biepicondylar humerus breadth (cm) 6.7 (0.5) 6.5 6.9 0.2 5.7–7.7 5.8 (0.5) 5.7 5.9 0.2 4.8–6.8 < 0.001 Bi-styloid breadth (cm) 5.7 (0.4) 5.6 5.9 0.2 5.2–6.8 5.1 (0.4) 4.9 5.2 0.1 4.4–6.4 < 0.001 Biepicondylar femur breadth (cm) 9.7 (0.7) 9.5 9.9 0.4 7.9–11.6 9.4 (0.8) 9.2 9.6 0.6 8.0–12.4 0.062 Transverse thoracic breadth (cm) 30.8 (2.6) 29.9 31.8 6.6 24.9–36.7 27.7 (1.8) 27.3 28.2 3.3 22.3–31.4 < 0.001 Body composition ALST (kg) 20.7 (4.1) 19.2 22.2 16.5 12.6–32.5 14.6 (2.6) 14.0 15.2 6.5 9.2–22.5 < 0.001 Fat mass (kg) 21.7 (6.9) 19.2 24.2 47.4 7.7–33.6 27.9 (7.2) 26.1 29.6 51.7 13.6–47.9 < 0.001 Bone mineral content 2.6 (0.6) 2.3 2.8 0.3 1.4–3.8 2.0 (0.3) 1.9 2.1 0.1 1.4–3.1 < 0.001 Residual mass 22.8 (3.9) 21.4 24.2 15.1 15.8–36.2 18.5 (2.8) 17.8 19.2 8.1 12.7–27.7 < 0.001 CI: confidence interval; SD: standard deviation; UL: upper limit; IL: inferior limit; Min-Max: minimum-maximum; ALST: appendicular lean soft tissue. The Kaiser-Meyer-Olkin test showed the sample adequacy and resulted in a value of 0.885, classified as meritorious ( 62 ) and the Barlett sphericity test yielded a Χ 2 of 3368.04 (p < 0.001), indicating homogeneous variance between groups. From the univariate regression (stepwise), the number of remaining variables to ALST (n = 08), FM (n = 05) and BMC (n = 06) showed high r 2 adj (0.68 to 0.88) for the independent common variables for the three dependents variables (Table 2 ). In bold, variables with statistically significant coefficients (p < 0.05), common in at least two of the dependent variables are shown. Table 2 Univariate regression for selecting common independent variables at least twice (bold). Appendicular lean soft tissue Fat mass Bone mineral content Variables Coefficient p Variables Coefficient p Variables Coefficient p Pectoral skinfold (mm) 0.13018 < 0.001 Media axillary skinfold (mm) 0.16083 0.012 Bi-styloid breadth (cm) 0.210010 0.020 Weight (kg) 0.13214 < 0.001 Pectoral skinfold (mm) -0.24240 < 0.001 Waist circumference (cm) -0.030637 0.001 Knee height (cm) 0.23779 0.009 Media thigh skinfold (mm) 0.12626 0.008 Triceps skinfold (mm) -0.020330 0.001 Bi-acromial breadth (cm) 0.30532 0.001 Weight (kg) 0.35620 < 0.001 Weight (kg) 0.038668 < 0.001 Biepicondylar humerus breadth (cm) 1.22979 < 0.001 Half arm span (cm) -0.29770 0.002 Half arm span (cm) 0.032912 0.005 Calf circumference (cm) 0.26318 0.001 Medial thigh circumference (cm) -0.028782 0.001 Media thigh skinfold (mm) -0.07881 < 0.001 Triceps skinfold (mm) -0.09662 0.003 R 2 = 0.88 R 2 = 0.85 R 2 = 0.68 R 2 : coefficient of determination. Next, a multivariate linear regression model was developed, simultaneously for the three dependent variables from variables selected in the univariate models. The categorical sex variable has not been previously tested in the models; however, it was added to the multivariate procedure due to its theoretical relevance, as demonstrated by their significant comparisons in Table 1 . The coefficients, variance inflation factor (VIF), Pillai’s trace, and precision and cross-validation results are shown in Table 3. Table 3. Coefficients, precision, and validation of a multicomponent anthropometric model to estimate body composition in older adults. Appendicular lean soft tissue Fat mass Bone mineral content VIF F p (Pillai's trace) Coefficients Intercept -10.21376 17.85412 -1.21230 Weight 0.19336 0.50239 0.01912 2.045 676.33 < 0.001 Half arm span 0.20139 -0.40498 0.02944 2.049 9.53 < 0.001 Triceps skinfold -0.04796 0.17292 -0.01267 2.544 4.17 0.008 Sex -3.16675 4.73524 -0.13021 2.407 11.33 < 0.001 Precision R 2 0.85 0.83 0.62 R 2 adjusted 0.85 0.83 0.61 SEE 1.65 3.16 0.30 Cross-validation PRESS 287.00 1066.84 9.75 Q 2 PRESS 0.84 0.81 0.58 SEE PRESS 0.18 0.34 0.03 R 2 : coefficient of determination; R 2 adjusted : adjusted coefficient of determination; SEE: standard error to estimate; PRESS: sum of squares of residuals; Q 2 PRESS : press coefficient of determination; SEE PRESS : press standard error of estimate; VIF: variance inflation factor; Sex: male = 0; female = 1. Higher precision and cross-validation values of PRESS, Q 2 PRESS, and low SEE PRESS were found for each dependent variable (Table 3). These results showed that the models are valid to simultaneously predict ALST, FM, and BMC, with accordance close to “1” (Q 2 PRESS ) and error close to “0” (S PRESS ). The model standardized residuals are normally distributed (p = 0.099) according to Fig. 1 . Discussion To the best of our knowledge, this is the first study that proposes a valid anthropometric model to simultaneously estimate FM, ALST, and BMC in older adults from a multicompartmental approach. DXA was used as a reference method due to its advantages in estimating all components by a single scan ( 63 ). Our proposed model with three anthropometric variables plus sex showed high prediction coefficients and low errors to simultaneously predict ALST, FM, and BMC. Since the BC is affected by sex ( 64 ), and changes in BC due to aging occur differently between men and women ( 65 ), the inclusion of the variable sex was made arbitrarily in the models generated in this study. Therefore, the current prediction equations are useful for estimating and monitoring ALST, FM, and BMC in older adults of both sexes. Current anthropometric models to estimate BC in older adults have several limitations, causing errors in the estimation of BC. Furthermore, they have been developed using a bi-compartmental model (2-C) that determines FM and FFM ( 27 , 28 , 66 ), and this model is based on there is a linear relationship between subcutaneous fat, total fat, and BD. However, this is not true, because during the aging process there is age-related adipose tissue redistribution that is, an accumulation of visceral and abdominal fat occurs ( 67 ). Additionally, these equations do not evaluate ALST and BMC which are components that change during aging. The Lean equations (68) to estimate % body fat showed a coefficient of determination (r 2 ) of 0.77 and 0.70 and standard error of estimate (SEE) of 4.1% and 4.7% for older adults men and women, respectively. However, our results for FM determination showed higher coefficient of determination (r 2 = 0.83) and lower errors (SEE = 3,16 kg). Progressive and metabolically unfavorable changes in BC have long been observed with aging ( 69 ). In a prospective study that investigated age-dependent changes over two decades, the main results found were an increase in BM, BMI, and FM until the age of approximately 70 and 75 years, after these parameters start to decrease ( 70 ). Regarding the changes in the SMM, the studies have shown a greater reduction in men than in women, with a more accentuated decline between 70 and 79 years old in both sexes ( 56 , 69 ). However, the pattern and rate of age-related changes in BC may vary by sex, ethnicity, physical activity level, and caloric intake ( 71 ). DXA is the most popular technique for measuring BC ( 42 ) and it has shown to be a reliable method of FFM during aging ( 72 ). Furthermore, DXA may be considered the current reference technique for assessing SMM and BC in research and clinical practice ( 42 ). A high correlation (r = 0.97) between DXA-measured ALST and SMM measured by magnetic resonance imaging (MRI) was reported for both men and women (18–92 years) ( 8 ). In the same way, DXA-derived LST was found to be significantly correlated with MRI-measured SMM (r = 0.94; p ≤ 0.001) in older women ( 73 ). In comparisons between DXA-measured FM and MRI-measured adipose tissue the associations were also high and significant ( r = 0.99; p ≤ 0.001) for older women ( 73 ). The principle of DXA depends on the property of X-rays to be attenuated in proportion to the composition and depth of the material the beam is crossed. The DXA scanner emits two different energy beams (40 and 70 keV). From the number of photons that are transmitted concerning the number detected the quantity of BMC and soft tissue (fat and FFM) can be determined ( 42 ). Therefore, DXA can be used as a reference method to propose equations using anthropometry for clinical and professional practice ( 74 ). The anthropometric measurements are performed in both the geriatric nutritional assessment and epidemiological studies because they are painless, safe, non-invasive, simple, and low-cost procedures, which permit the estimation of the body components and also the calculation of nutritional indicators using predictive equations ( 32 ). The main anthropometric measurements used in the older adults for this purpose are weight, height, the calf and waist circumferences, as well as the triceps, biceps, subscapular and suprailiac skinfolds (32). The current investigation has several strengths. As far as we know, this is the first study that proposes equations to estimate the main components of BC from the same anthropometric variables for older adults. This implies a reduction in the prediction error and facilitates its use in epidemiological studies. Another positive point is that we included the variable sex in the generated models, facilitating the application in large groups of both sexes. Despite all the research efforts in this study, there were still some limitations: for example, DXA is not a gold standard for older adults’ body composition. However, the current state-of-the-art method for body composition measurement in the four compartments model (4-C models) at the molecular level, as it includes the evaluation of the main FFM components, thus reducing the effect of biological variability. Nonetheless, it requires sophisticated and highly specialized technical equipment; it implies the propagation of measurement errors, difficult to apply in certain population groups, and is time-consuming. Furthermore, it has high costs, making it difficult to use on large samples ( 75 ). Nevertheless, DXA represents a reference method for the assessment of human BC in the research field ( 63 , 76 ) and it is widely considered the gold standard for BC assessment in clinical practice because of its advantages ( 74 ). Moreover, reference values of BC assessed by DXA on adults over 60 years old are available from the National Health and Nutrition Examination Survey 1999–2004 and other studies on the local population ( 77 ). Although it is a program designed to assess the health of adults and children in the United States, these reference values should be helpful in the evaluation of a variety of adult abnormalities involving fat, LST, and bone. As it was hypothesized, using a multivariate regression model, simple anthropometric measures can be used to simultaneously estimate body components (ALST, FM, and BMC) in older adults of both sexes. As a practical simulation, an older adult male “A” with measurements of weight (66.3 kg), HAS (80.5 cm), TrSk (16 mm), and sex (0), when applied to our model, would have the estimated values of 18.1 kg, 21.3 kg and 2.2 kg for ALST, FM, and BMC, respectively. Their true measured values (DXA) were 18.2 kg, 20.8 kg, and 2.2 kg. If the equation is applied to an older adult woman “B” with values of weight (58.6 kg), HAS (81.5 cm), TriSK (26 mm), and sex ( 1 ) the estimated values for ALST, FM, and BMC would be: 13.1 kg, 23.5 kg and 1.9 kg, correspondingly. As noted, the values are close to the measured DXA values for ALST (13.2 kg), FM (23.4 kg), and BMC (2.0 kg). These values can be compared with the reference values National Health and Nutrition Examination Survey (NHANES) ( 77 ) and be useful for many applications in clinical and field practice. For example, using the criteria proposed by the FNIH (cutoffs < 19.75 for men and < 15.02 for women) we can classify both older adults with sarcopenia ( 78 ). Since older adult “A” presented predicted ALST values of 18.1 kg and older adult B of 13.1 kg. These findings are highly relevant as they allow permanent following/monitoring of excessive accumulation of FM, declines in BMC and ALST, as risks to older adults throughout the life course ( 79 , 80 ). Thus, keeping the balance rate of fat, muscle and bone are essential to preserving metabolic homeostasis, and health status and positively contributes to successful aging ( 74 ). For this reason, the assessment of BC in older adults is critical and could be an additional preventive strategy for age-related diseases ( 74 ), which may result in sarcopenia ( 9 , 48 , 81 ), osteoporosis ( 14 ) sarcopenic obesity ( 64 ) osteosarcopenic obesity ( 2 ) and osteosarcopenia ( 11 ). This should impair muscle strength, and functional capacity, as well as greater morbidity and mortality in older adults ( 4 , 5 ). Therefore, the current prediction equations could increase the available options for the estimation of body composition in older adults. To ensure dissemination and accessibility, an assessment of the main body components based on our predictive models can be found in an excel file (Additional file 1) in the following link ( http://posgraduacao.eerp.usp.br/files/Model_BodyComposition_OlderAdults.xlsx ). Lastly, future studies should evaluate the efficiency of these equations applied in longitudinal and intervention studies. Conclusion Our findings demonstrated that the anthropometric prediction equations developed in this study provide a reliable, practical, and low-cost instrument to assess the components that most change during the aging process. These results suggest that the equations can be valid alternative and reliable information about BC in older adults since the internal validation method PRESS presented high internal validity, high coefficients of determination, and low prediction errors. Abbreviations Body composition (BC) Skeletal muscle mass (SMM) Fat mass (FM) Fat-free mass (FFM) Bone mineral content (BMC) Lean soft tissue (LST) Appendicular lean soft tissue (ALST) Predicted residual error sum of squares (PRESS) Half arm span (HAS) Triceps skinfold (TriSK) Standard error to estimate (SEE) Body density (BD) Dual energy X-ray absorptiometry (DXA) Magnetic resonance imaging (MRI) Declarations Ethics approval and consent to participate. The study was approved by the Ethics Review Board at University Hospital, the University of São Paulo at Ribeirão Preto College of Nursing (EERP/USP), Brazil, with CAAE number: 18416619.3.0000.5393, and written informed consent was obtained from all subjects. All methods were carried out following the Declaration of Helsinki. Consent for publication Not applicable Availability of data and materials The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request. Competing interests The authors declare that they have no competing interests. Funding This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001. This study was supported by the National Council for Scientific and Technological Development (CNPq-Brazil) under Grant 142078/2019-0. Author’s contributions ACRV: Conceptualization; data curation; formal analysis; methodology; writing-original draft. LV: formal analysis; methodology; PPA: Data curation; formal analysis; writing-original draft. APS: Data curation; formal analysis; writing-original draft. MFTJ: Data curation; formal analysis; writing-original draft. LSLS: Data curation; formal analysis; writing-original draft. TCA: Data curation; formal analysis; writing-original draft. EF: Supervision; writing reviews and editing. JLGS: Supervision; writing reviews and editing. VRP: Supervision; writing reviews and editing. JM: Supervision; writing reviews and editing. DRLM: Conceptualization; supervision; writing-review and editing. Acknowledgments Jorge Mota, Jose Luis Garcia-Soidan e Vicente Romo-Perez were supported by IACObus-2021-2022 program. References Jiang Y, Zhang Y, Jin M, Gu Z, Pei Y, Meng P. Aged-Related Changes in Body Composition and Association between Body Composition with Bone Mass Density by Body Mass Index in Chinese Han Men over 50-year-old. PLoS One. 2015 Jun 19;10(6):e0130400. doi: 10.1371/journal.pone.0130400 Banitalebi E, Ghahfarrokhi MM, Dehghan M. Effect of 12-weeks elastic band resistance training on MyomiRs and osteoporosis markers in elderly women with Osteosarcopenic obesity: a randomized controlled trial. 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Rossini-Venturini","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAn0lEQVRIiWNgGAWjYPACGxDBRpKWNNK1HCZBC//s5oefK9vOJ86f3cD2uIIYLRJ3jhlLnm27nbjhzgF2wzNEWXMjwYyx4QxQi0QCm2QDMTrkb6R/A2o5lzh/BrFaDG7kAG2pOJDYcINYLYY3coolGyqSjTfcOdhuSJQWuRvpGz82GNjJzp/dfOwhUVoQQIKRRA1ALaRqGAWjYBSMghEDAAl6NDpuTCGZAAAAAElFTkSuQmCC","orcid":"","institution":"University of São Paulo","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Ana","middleName":"Claudia","lastName":"Rossini-Venturini","suffix":""},{"id":119679580,"identity":"aa956fef-d729-4c18-a35e-1d6cd1494c03","order_by":1,"name":"Lucas Veras","email":"","orcid":"","institution":"University of Porto","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Lucas","middleName":"","lastName":"Veras","suffix":""},{"id":119679583,"identity":"82058dcf-0b8f-4845-a361-247aa5f7060a","order_by":2,"name":"Pedro Pugliesi Abdalla","email":"","orcid":"","institution":"University of São Paulo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Pedro","middleName":"Pugliesi","lastName":"Abdalla","suffix":""},{"id":119679584,"identity":"6ed35f8c-3a0e-43ac-a809-3716bf48721e","order_by":3,"name":"André Pereira Santos","email":"","orcid":"","institution":"University of São Paulo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"André","middleName":"Pereira","lastName":"Santos","suffix":""},{"id":119679586,"identity":"bd15094c-7aa2-4980-95cf-c54ee552f13d","order_by":4,"name":"Márcio Fernando Tasinafo Junior","email":"","orcid":"","institution":"University of São Paulo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Márcio","middleName":"Fernando Tasinafo","lastName":"Junior","suffix":""},{"id":119679588,"identity":"3ebcb94f-f653-4c5c-b20d-7a17c40ad015","order_by":5,"name":"Leonardo Santos Lopes Silva","email":"","orcid":"","institution":"University of São Paulo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Leonardo","middleName":"Santos Lopes","lastName":"Silva","suffix":""},{"id":119679589,"identity":"a1d9e1d4-f3c7-44ad-bd2a-eb7016d97a9c","order_by":6,"name":"Thiago Cândido Alves","email":"","orcid":"","institution":"University of São Paulo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Thiago","middleName":"Cândido","lastName":"Alves","suffix":""},{"id":119679590,"identity":"7fcaeb15-b603-4de6-a1c9-12108b33fb0e","order_by":7,"name":"Eduardo Ferrioli","email":"","orcid":"","institution":"University of São Paulo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Eduardo","middleName":"","lastName":"Ferrioli","suffix":""},{"id":119679591,"identity":"fd766efa-f15a-4ff6-bccb-db7807ccefb7","order_by":8,"name":"Vicente Romo-Perez","email":"","orcid":"","institution":"University of Vigo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Vicente","middleName":"","lastName":"Romo-Perez","suffix":""},{"id":119679593,"identity":"570c02ce-3fc8-4d2d-8c1c-ed00b2d9a220","order_by":9,"name":"Jose Luis Garcia-Soidan","email":"","orcid":"","institution":"University of Vigo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Jose","middleName":"Luis","lastName":"Garcia-Soidan","suffix":""},{"id":119679595,"identity":"79cce20d-240c-4431-a9bb-a070209190f8","order_by":10,"name":"Jorge Mota","email":"","orcid":"","institution":"University of Porto","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Jorge","middleName":"","lastName":"Mota","suffix":""},{"id":119679597,"identity":"757c3428-8d17-40d3-9ec1-c35772550a94","order_by":11,"name":"Dalmo Roberto Lopes Machado","email":"","orcid":"","institution":"University of São Paulo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Dalmo","middleName":"Roberto Lopes","lastName":"Machado","suffix":""}],"badges":[],"createdAt":"2022-07-07 14:14:18","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-1835649/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-1835649/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1186/s12877-023-03752-1","type":"published","date":"2023-02-09T18:44:17+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":23778666,"identity":"e4a35e95-7d0c-41dc-9bfd-f0c648329a9c","added_by":"auto","created_at":"2022-07-12 17:32:13","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":274669,"visible":true,"origin":"","legend":"\u003cp\u003eModel standardized residuals\u003c/p\u003e\u003cp\u003eALST: appendicular lean soft tissue; FM: fat mass; BMC: bone mineral content.\u003c/p\u003e","description":"","filename":"Figure1.png","url":"https://assets-eu.researchsquare.com/files/rs-1835649/v1/e7aa97c167f3712f72e39255.png"},{"id":44718929,"identity":"d7720d5d-5556-4c84-94e9-0d5007d2abe4","added_by":"auto","created_at":"2023-10-16 18:52:14","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":636732,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-1835649/v1/2401e012-0bcb-440a-a344-7fd6b7ec5648.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Multicompartment body composition analysis in older adults: a cross-sectional study","fulltext":[{"header":"Background","content":"\u003cp\u003e \u003cdiv class=\"BlockQuote\"\u003e \u003cp\u003eMuscle, fat, and bone are three main components of interest in the body composition (BC) field (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e). Aging processe involve proportional changes in these components (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e) due to decreased levels of anabolic steroids and sex hormones (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e). These alterations in the older adults\u0026rsquo; BC have a great impact on their health and quality of life, expose them to the risk of malnutrition, and could lead to conditions of disability (\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e). Skeletal muscle mass (SMM) has various essential physiological functions in humans and its maintenance is important to keep the body healthy, especially during aging. Thus, the reduction of SMM impairs muscle strength, and functional capacity, increasing the chances of morbidity and mortality (\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e, \u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e). As result, diverse functional and metabolic disorders in older adults also can occur (\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e, \u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e). As a large proportion of SMM (\u0026cong;\u0026thinsp;74%) is found in the extremities and the main proportion of appendicular lean soft tissue (ALST) is SMM (\u0026cong;\u0026thinsp;76%) (\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e). So, the ALST is a representative measure of the SMM. In addition, ALST is used to identify sarcopenia (\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e), sarcopenic obesity (\u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e), osteosarcopenia (\u003cspan citationid=\"CR11\" class=\"CitationRef\"\u003e11\u003c/span\u003e), and osteosarcopenic obesity (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e). In turn, the bone mineral content (BMC) presents important variations throughout the olders\u0026rsquo; life. Peak BMC occurs in the third decade of life and declines over the years (\u003cspan citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e). This reduction is similar in men and women before 50 years of age, but after this, the differences become very distinct against women because of menopause (\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e). This skeletal reduction restrains bone strength and can cause osteopenia and osteoporosis. The World Health Organization defines osteopenia and osteoporosis as a T score equal to or less than \u0026minus;\u0026thinsp;1 and \u0026minus;\u0026thinsp;2.5 standard deviations, respectively; below the peak bone mass of a young healthy cohort (\u003cspan citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e). Osteoporosis increases the risk of fractures and is an important health problem faced by older adults (\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e). Meanwhile, fat mass (FM) presents an increase during aging (\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e). From the 70 years old, the FM increases (7.5%) in a similar way for both sexes (\u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e), becoming one of the main risk factors for chronic diseases (\u003cspan citationid=\"CR17\" class=\"CitationRef\"\u003e17\u003c/span\u003e), some types of cancer (\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e), physical disability (\u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e) and mortality (\u003cspan citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e). In this sense, changes in ALST, BMC, and FM during senescence have a great impact on their health (\u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e), quality of life, and functional capacity (\u003cspan citationid=\"CR22\" class=\"CitationRef\"\u003e22\u003c/span\u003e). Follow-ups and interventional studies are desirable at this stage of life (\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e). To monitor this BC variability, simple and low-cost methods are required (\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eSeveral equations to predict BC using anthropometric measurements have been developed to determine FM and fat-free mass (FFM). Body density (BD) is usually thereferential method for estimating body fat by hydrostatic weighing (\u003cspan additionalcitationids=\"CR25 CR26 CR27\" citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR28\" class=\"CitationRef\"\u003e28\u003c/span\u003e). However, these models have limitations regarding the estimation of older\u0026rsquo;s BD and BC (\u003cspan citationid=\"CR29\" class=\"CitationRef\"\u003e29\u003c/span\u003e). The traditional bi-compartmental (2-C) model is based on the assumption that there is a linear relationship between subcutaneous fat, total fat, and BD. However, the correlation between total and subcutaneous body fat decreases with age (\u003cspan citationid=\"CR30\" class=\"CitationRef\"\u003e30\u003c/span\u003e, \u003cspan citationid=\"CR31\" class=\"CitationRef\"\u003e31\u003c/span\u003e). Perhaps it is due to; 1) the redistribution of FM from the extremities to the visceral area, and 2) due to fat infiltration in the SMM. Thus, there is an overestimation of the BD, and consequently, the FM is underestimated (\u003cspan citationid=\"CR32\" class=\"CitationRef\"\u003e32\u003c/span\u003e). Another worrying limitation is to assume a constant density of 0.9007 g/cm\u003csup\u003e3\u003c/sup\u003e and 1.100 g/cm\u003csup\u003e3\u003c/sup\u003e for the FM (\u003cspan citationid=\"CR33\" class=\"CitationRef\"\u003e33\u003c/span\u003e) and FFM (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e), respectively. However, the natural aging process causes a progressive bone demineralization (\u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e) and changes in the hydration of the FFM, causing a decrease in its density (\u003cspan citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e) which also affects the FM estimate (\u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e, \u003cspan citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e). Furthermore, these 2-C equations do not evaluate other components, such as ALST and BMC, fundamental components in vulnerable peoples (\u003cspan citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e) and older adults (\u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e). Moreover, the ALST is a consensual parameter for SMM among agencies. It is equivalent to muscle tissue in arms and legs, except for a small amount of connective tissue and skin (\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eSince the methodological advances are necessary to analyze the BC in a more precise and detailed way, providing a broader understanding of the metabolic functions of each component (\u003cspan citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e). Among imaging analysis methods, dual energy X-ray absorptiometry (DXA) is widely used because its offers advantages such as low cost, speed of measurement (whole-body scans need less than 20 min), noninvasive, efficiency in the simultaneous determination of several components in a single scan (\u003cspan citationid=\"CR41\" class=\"CitationRef\"\u003e41\u003c/span\u003e), and their radiation exposure are considered small and safe for repeated measures (\u0026lt;\u0026thinsp;1 mrem for whole-body scans) (\u003cspan citationid=\"CR42\" class=\"CitationRef\"\u003e42\u003c/span\u003e). Furthermore, DXA is considered a 3-C model (\u003cspan citationid=\"CR43\" class=\"CitationRef\"\u003e43\u003c/span\u003e, \u003cspan citationid=\"CR44\" class=\"CitationRef\"\u003e44\u003c/span\u003e), once it can accurately measure FM, BMC, and appendicular lean soft tissue (ALST) (\u003cspan citationid=\"CR45\" class=\"CitationRef\"\u003e45\u003c/span\u003e). ALST is mainly muscle (\u0026cong;\u0026thinsp;76%) (\u003cspan citationid=\"CR46\" class=\"CitationRef\"\u003e46\u003c/span\u003e, \u003cspan citationid=\"CR47\" class=\"CitationRef\"\u003e47\u003c/span\u003e) and a large proportion (\u0026cong;\u0026thinsp;74%) of SMM is in the extremities (\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e). Thus, ALST is the strongest predictor of SMM (\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e) and is widely used in sarcopenia consensus (\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e, \u003cspan citationid=\"CR48\" class=\"CitationRef\"\u003e48\u003c/span\u003e). However, BC assessment with sophisticated equipment such as DXA is restricted to specific professionals, requiring a specialized structure. Then, why anthropometric measurements are simple and with a low cost associated (\u003cspan citationid=\"CR49\" class=\"CitationRef\"\u003e49\u003c/span\u003e), their use has been presented as valid alternatives for estimating BC in a multicompartmental approach in children and adolescents of both sexes (\u003cspan citationid=\"CR50\" class=\"CitationRef\"\u003e50\u003c/span\u003e, \u003cspan citationid=\"CR51\" class=\"CitationRef\"\u003e51\u003c/span\u003e), sarcopenia risks (\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e, \u003cspan citationid=\"CR52\" class=\"CitationRef\"\u003e52\u003c/span\u003e) lipodystrophy of seropositive patients (\u003cspan citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e, \u003cspan citationid=\"CR53\" class=\"CitationRef\"\u003e53\u003c/span\u003e) and muscle loses in older adults (\u003cspan citationid=\"CR54\" class=\"CitationRef\"\u003e54\u003c/span\u003e). Accordingly, this proposal may also be viable for older adults, as long as it is a practical, simple and non-invasive tool. So, the objective of this study was to propose and validate a multi-compartmental anthropometric model for the prediction of fat, bone, and musculature components in older adults of both sexes. Our hypothesis is that body composition can be estimated through anthropometric measurements.\u003c/p\u003e \u003c/div\u003e \u003c/p\u003e"},{"header":"Methods","content":"\u003cdiv id=\"Sec3\" class=\"Section2\"\u003e \u003ch2\u003eDesign and Study population\u003c/h2\u003e \u003cp\u003eIn this study, we adopted a cross-sectional design to develop and validate a multicomponent anthropometric model to simultaneously estimate LST, BMC, and FM. The study was conducted from October 2016 to May 2017. The study sample was derived from physically independent community-dwelling older adults in a city in southeastern Brazil. The inclusion criteria were: adults aged 60\u0026ndash;85 years, of both sexes, who walk independently. The exclusion criteria were: the presence of diseases that restrict mobility or muscle strength; absence of unstable cardiovascular condition; acute infection; tumor; back pain; prostheses, individuals with a diagnosis of cancer or uncontrolled diseases, who presented sequel of stroke, experienced a weight loss more than three kilograms (kg) in the last 3 months, had a cognitive limitation that restricts understanding and taking tests, who did not complete all the stages or desired to withdraw from the study.\u003c/p\u003e \u003cp\u003e The study was approved by the Ethical Review Board of Hospital das Clinicas at the Medical School of the University of Sao Paulo (HC-FMRP/USP), following the ethical guidelines outlined in the 1975 Helsinki Declaration. Written informed consents were obtained from all individuals included in the study, after a brief explanation of the study objectives and evaluations. This manuscript followed the guidelines from The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) conference list, and the completed checklist is attached.\u003c/p\u003e \u003cp\u003eThe sample size calculation was considered the desired maximum error (ε) and degree of confidence (Zy), previously knowing the population variability (σ\u003csup\u003e2\u003c/sup\u003e) (\u003cspan citationid=\"CR55\" class=\"CitationRef\"\u003e55\u003c/span\u003e). For this, we used the variable with the greatest variability (FM; SD\u0026thinsp;=\u0026thinsp;8.7 kg) expected for such a population (\u003cspan citationid=\"CR56\" class=\"CitationRef\"\u003e56\u003c/span\u003e). Once the predetermined error estimate (ε\u0026thinsp;\u0026le;\u0026thinsp;1.8 kg) and maximum desired error (5%) the ideal n for the study (\u003cspan citationid=\"CR55\" class=\"CitationRef\"\u003e55\u003c/span\u003e) was defined (n\u0026thinsp;=\u0026thinsp;90).\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec4\" class=\"Section2\"\u003e \u003ch2\u003eStudy protocol\u003c/h2\u003e \u003cp\u003eA multidisciplinary health-trained team (nurses, nutritionists, pharmacists, physical education professors, physicians, and physiotherapists) performed data collection. All procedures, for each participant, were completed during one visit to the laboratories at the Hospital das Clinicas at the Medical School of the University of Sao Paulo at Ribeirao Preto (HCFMRP/USP). Participants came to the laboratory after an overnight fast (8h fast), abstaining from vigorous exercises, and no caffeine and alcohol during the preceding 24h. Before the measurements, the subjects were asked to empty their bladders. A total-body DXA scan was executed according to the manufacturer's guidelines. The anthropometric measures were taken according to the literature guidelines (\u003cspan citationid=\"CR57\" class=\"CitationRef\"\u003e57\u003c/span\u003e), whose procedures are summarized below.\u003c/p\u003e \u003cdiv id=\"Sec5\" class=\"Section3\"\u003e \u003ch2\u003eThe dependent variables\u003c/h2\u003e \u003cp\u003e\u003cdiv class=\"BlockQuote\"\u003e\u003cp\u003e Whole and regional body composition were determined by DXA (Hologic\u0026reg; scanner, model QDR4500W; version 11.2, Bedford, MA). The DXA measurements included absolute values of appendicular lean soft tissue (ALST, kg), bone mineral content (BMC, kg), and fat mass (FM, kg), considered dependent variables. As the BMC represents the gray portion of bone, the bone adjustment was performed by multiplying the BMC by 1.0436 (\u003cspan citationid=\"CR58\" class=\"CitationRef\"\u003e58\u003c/span\u003e). The ALST was obtained through the sum of the lean soft tissue (LST) of the lower and upper limbs on both sides (\u003cspan citationid=\"CR59\" class=\"CitationRef\"\u003e59\u003c/span\u003e). The DXA measurements were electronically transferred to an external HD and organized into a general data sheet without manual typing.\u003c/p\u003e\u003c/div\u003e\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv id=\"Sec6\" class=\"Section2\"\u003e \u003ch2\u003eThe independent variables\u003c/h2\u003e \u003cp\u003e \u003cdiv class=\"BlockQuote\"\u003e \u003cp\u003eThe participant\u0026rsquo;s body mass and height were measured with a digital scale (Filizola\u0026reg; (model Personal, \u003cem\u003eCampo Grande\u003c/em\u003e, MS) and a hall fixed stadiometer (Sanny\u0026reg; Professional \u0026ndash; ES2020), respectively. The skinfolds (n\u0026thinsp;=\u0026thinsp;09) were measured with Lange caliper with precision in mm, on the right side of the body in the regions. The circumferences (n\u0026thinsp;=\u0026thinsp;08) were realized using inelastic and inextensible tape (Sanny\u0026reg;). The widths (n\u0026thinsp;=\u0026thinsp;08) were measured with Pachymeter (Sanny\u0026reg;). In addition, knee height and half arm span (HAS) were measured using a Sanny\u0026reg; segmometer. All these procedures followed conventional standardization (\u003cspan citationid=\"CR60\" class=\"CitationRef\"\u003e60\u003c/span\u003e). The anthropometric measurements of our laboratory remain within the limits of reliability (\u003cspan citationid=\"CR51\" class=\"CitationRef\"\u003e51\u003c/span\u003e).\u003c/p\u003e \u003c/div\u003e \u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec7\" class=\"Section2\"\u003e \u003ch2\u003eStatistical analysis\u003c/h2\u003e \u003cp\u003eThe basic analysis involved descriptive statistics using measures of central tendency to describe the characteristics of the sample. To verify the data normality, the Shapiro\u0026ndash;Wilk test was applied. Comparisons between sex were performed using Student\u0026rsquo;s t-test for independent samples. For the Multicompartmental anthropometric equation development, we adopted previous procedures (\u003cspan citationid=\"CR50\" class=\"CitationRef\"\u003e50\u003c/span\u003e, \u003cspan citationid=\"CR51\" class=\"CitationRef\"\u003e51\u003c/span\u003e), briefly described below.\u003c/p\u003e \u003cp\u003eThrough the determination of 30 independent variables plus the sex for the prediction of the 3 dependent variables, the multivariate regression model (nYm\u0026thinsp;=\u0026thinsp;nX(r\u0026thinsp;+\u0026thinsp;1) (r\u0026thinsp;+\u0026thinsp;1) βm\u0026thinsp;+\u0026thinsp;nεm) by diagonal mutual analysis, parameter estimation, and the least squares errors method was used (\u003cspan citationid=\"CR61\" class=\"CitationRef\"\u003e61\u003c/span\u003e) by R Statistical Software (version 4.1.2, R Foundation for Statistical Computing, Vienna, Austria). The criteria for selection and reduction of independent variables followed the following steps: a) factor analysis and model adequacy (Kaiser-Meyer-Olkin) and Sphericity test (Bartlett) were performed to verify the suitability of the sample; b) univariate linear regression to determine all common independent variables for each dependent variable (ALST, BMC, and FM), with significantly less than 5%; c) multivariate linear regression to estimate the parameters and Pillai approximation method for showing possible variables exclusions; d) testing of the remaining model (enter - univariate method), with estimated values of VIF (\u0026lt;\u0026thinsp;10.0) and multicollinearity (L\u0026thinsp;\u0026lt;\u0026thinsp;1000) maximum permitted; e) adjustments by Pillai approach to testing the F values; f) as the variable sex is a categorical variable, it could not enter in the factor analysis. However, it will be added to the multivariate model due to its theoretical relevance and assumption of improving the model; g) then multivariate β parameters were determined, with the proposition of equations and residual distribution for each dependent variable; h) Akaike information criterion (AIC) statistic to ensure greater quality and simplicity of the statistical model. The details of the statistical procedures have been previously described in adolescents of both sexes (\u003cspan citationid=\"CR50\" class=\"CitationRef\"\u003e50\u003c/span\u003e, \u003cspan citationid=\"CR51\" class=\"CitationRef\"\u003e51\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eFinally, the predicted residual error sum of squares (PRESS) statistic was used to measure the effectiveness of the predicted equations for each dependent variable. The procedure may be understood as design efficiency in estimating the actual parameters by a virtual simulation that is, from the exclusion of an observation, equations are proposed with the remaining sample and replicated through cross-validation for each participant that was excluded. For validation, we follow the following steps: a) the correlation coefficients were estimated between predicted and measured values and b) cross-validation by PRESS method, coefficients of determination (Q\u003csup\u003e2\u003c/sup\u003e\u003csub\u003ePRESS\u003c/sub\u003e), and error (S\u003csub\u003ePRESS\u003c/sub\u003e) for each dependent variable (ALST, BMC, and FM) (\u003cspan citationid=\"CR61\" class=\"CitationRef\"\u003e61\u003c/span\u003e).\u003c/p\u003e \u003c/div\u003e"},{"header":"Results","content":"\u003cp\u003eTable \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003e shows anthropometric and body composition measures of the eligible participants. The means of all variables are within the confidence interval (95% CI), within the range limits for normal trends of distribution. Men were statistically taller, heavier, larger, and longer in most comparisons with women. Also had higher values of ALST, BMC, and residual mass. On other hand, women presented higher skinfolds, fat mass, and circumferences of hip and thigh values (\u003cem\u003ep\u003c/em\u003e\u0026thinsp;\u0026lt;\u0026thinsp;0.05).\u003c/p\u003e\n\u003cdiv class=\"gridtable\"\u003e\u0026nbsp;\u003ctable border=\"1\" id=\"Tab1\"\u003e\n \u003ccaption language=\"En\"\u003e\n \u003cdiv class=\"CaptionNumber\"\u003eTable 1\u003c/div\u003e\n \u003cdiv class=\"CaptionContent\"\u003e\n \u003cp\u003e\u0026ndash; Descriptive values of anthropometric and body composition variables in older adults, difference test by sex.\u003c/p\u003e\n \u003c/div\u003e\n \u003c/caption\u003e\n \u003ccolgroup cols=\"13\"\u003e\u003c/colgroup\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth align=\"left\" style=\"width: 13.9464%;\"\u003e\u0026nbsp;\u003c/th\u003e\n \u003cth align=\"left\" colspan=\"5\" style=\"width: 22.838%;\"\u003e\n \u003cp\u003eMen (n\u0026thinsp;=\u0026thinsp;31)\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" colspan=\"5\" style=\"width: 22.838%;\"\u003e\n \u003cp\u003eWomen (n\u0026thinsp;=\u0026thinsp;69)\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" style=\"width: 3.8977%;\"\u003e\u0026nbsp;\u003c/th\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003cth align=\"left\" style=\"width: 13.9464%;\"\u003e\u0026nbsp;\u003c/th\u003e\n \u003cth align=\"left\" rowspan=\"2\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003eMean (SD)\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" colspan=\"2\" style=\"width: 6.8819%;\"\u003e\n \u003cp\u003e95% CI\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" rowspan=\"2\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003eVariance\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" rowspan=\"2\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003eMin - Max\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" rowspan=\"2\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003eMean (SD)\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" colspan=\"2\" style=\"width: 6.8819%;\"\u003e\n \u003cp\u003e95% CI\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" rowspan=\"2\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003eVariance\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" rowspan=\"2\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003eMin - Max\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" rowspan=\"2\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u003cem\u003ep\u003c/em\u003e\u003c/p\u003e\n \u003c/th\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003cth align=\"left\" style=\"width: 13.9464%;\"\u003e\u0026nbsp;\u003c/th\u003e\n \u003cth align=\"left\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003eIL\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003eUL\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003eIL\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003eUL\u003c/p\u003e\n \u003c/th\u003e\n \u003c/tr\u003e\n \u003c/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eAge (years)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e72 (7.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e69.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e74.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e57.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e60.0\u0026ndash;88.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e69.8 (5.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e68.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e71.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e35.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e60.0\u0026ndash;85.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.133\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003e\u003cem\u003eAnthropometric variables\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.8977%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eHeight (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e168.0 (8.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e165.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e170.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e64.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e150.5\u0026ndash;188.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e156.2 (6.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e154.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e157.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e35.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e145.0\u0026ndash;174.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eWeight (kg)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e71.7 (13.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e66.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e76.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e177.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e42.0\u0026ndash;108.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e65.8 (11.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e63.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e68.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e130.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e39.0\u0026ndash;102.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.022\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eKnee height (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e53.6 (2.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e52.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e54.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e7.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e49.1\u0026ndash;61.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e49.6 (2.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e49.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e50.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e4.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e45.0\u0026ndash;54.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eHalf arm span (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e87.4 (4.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e85.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e89.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e21.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e78.7\u0026ndash;101.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e80.9 (3.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e79.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e81.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e13.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e69.1\u0026ndash;89.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003e\u003cem\u003eSkinfold\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.8977%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eSubscapular skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e23.2 (8.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e20.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e26.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e72.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e6.0\u0026ndash;37.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e28.3 (8.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e26.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e30.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e77.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e8.0\u0026ndash;47.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.007\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eTriceps skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e15.1 (5.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e13.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e17.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e34.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e4.0\u0026ndash;26.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e25.8 (6.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e24.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e27.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e48.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e9.0\u0026ndash;46.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBiceps skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e8.1 (3.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e6.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e9.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e12.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e3.0\u0026ndash;15.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e15.2 (5.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e13.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e16.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e28.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.0\u0026ndash;34.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eMedia axillary skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e18.5 (7.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e15.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e21.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e57.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e4.0\u0026ndash;30.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e23.7 (6.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e22.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e25.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e46.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.0\u0026ndash;41.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003ePectoral skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e16.9 (5.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e15.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e18.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e28.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e4.0\u0026ndash;26.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e14.7 (6.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e13.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e16.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e40.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e4.0\u0026ndash;40.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.094\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eSuprailiac skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e19.7 (9.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e16.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e23.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e95.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.0\u0026ndash;39.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e29.3 (7.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e27.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e31.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e63.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e8.0\u0026ndash;50.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eVertical abdominal skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e25.9 (8.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e22.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e28.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e68.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.0\u0026ndash;39.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e33.6 (8.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e31.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e35.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e74.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e6.0\u0026ndash;55.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eMedia Thigh skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e18.1 (7.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e15.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e20.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e56.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.0\u0026ndash;40.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e32.2 (11)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e29.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e34.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e120.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e9.0\u0026ndash;65.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eCalf skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e11.9 (6.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e9.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e14.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e41.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e2.0\u0026ndash;34.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e23.8 (7.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e22.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e25.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e55.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e6.0\u0026ndash;45.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003e\u003cem\u003eCircumference\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.8977%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eChest circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e97.8 (9.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e94.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e101.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e84.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e82.0\u0026ndash;116.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e92.9 (7.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e91.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e94.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e58.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e72.0\u0026ndash;115.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.007\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eArm circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e28.8 (3.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e27.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e30.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e12.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e20.0\u0026ndash;36.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e29.9 (3.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e29.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e30.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e14.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e22.0\u0026ndash;40.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.178\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eForearm circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e26.0 (2.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e25.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e26.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e3.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e20.0\u0026ndash;30.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e23.8 (2.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e23.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e24.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e5.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e19.0\u0026ndash;30.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eWaist circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e92.2 (11.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e88.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e96.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e122.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e68.5\u0026ndash;115.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e86.2 (10.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e83.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e88.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e100.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e65.0\u0026ndash;113.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.009\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eAbdominal circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e96.1 (10.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e92.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e100.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e118.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e68.0\u0026ndash;115.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e95.4 (10.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e92.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e98.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e119.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e70.0\u0026ndash;120.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.766\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eHip circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e96.8 (6.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e94.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e99.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e43.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e80.0\u0026ndash;111.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e100.6 (9.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e98.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e102.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e81.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e81.5\u0026ndash;128.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.038\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eMedial thigh circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e47.1 (5.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e45.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e49.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e31.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e32.0\u0026ndash;57.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e52.8 (6.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e51.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e54.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e40.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e37.5\u0026ndash;69.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eCalf circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e35.6 (3.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e34.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e36.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e12.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e26.5\u0026ndash;42.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e34.9 (3.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e34.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e35.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e8.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e25.2\u0026ndash;42.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.268\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003e\u003cem\u003eGirth\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.8977%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBi-acromial breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e39.9 (2.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e38.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e40.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e7.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e33.6\u0026ndash;44.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e37 (2.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e36.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e37.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e4.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e32.9\u0026ndash;45.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBi-iliac breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e31.3 (2.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e30.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e32.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e6.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e28.1\u0026ndash;39.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e30.8 (2.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e30.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e31.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e4.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e26.2\u0026ndash;37.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.268\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBi-trochanteric breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e33.8 (1.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e33.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e34.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e2.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e31.4\u0026ndash;39.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e33.3 (2.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e32.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e33.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e5.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e28.7\u0026ndash;39.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.289\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBi-maleolar breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e7.0 (0.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e6.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e7.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e6.0\u0026ndash;8.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e6.3 (0.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e6.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e6.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.4\u0026ndash;7.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBiepicondylar humerus breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e6.7 (0.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e6.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e6.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.7\u0026ndash;7.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e5.8 (0.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e5.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e5.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e4.8\u0026ndash;6.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBi-styloid breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e5.7 (0.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e5.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e5.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e5.2\u0026ndash;6.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e5.1 (0.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e4.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e5.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e4.4\u0026ndash;6.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBiepicondylar femur breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e9.7 (0.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e9.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e9.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e7.9\u0026ndash;11.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e9.4 (0.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e9.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e9.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e8.0\u0026ndash;12.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e0.062\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eTransverse thoracic breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e30.8 (2.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e29.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e31.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e6.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e24.9\u0026ndash;36.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e27.7 (1.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e27.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e28.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e3.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e22.3\u0026ndash;31.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003e\u003cem\u003eBody composition\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.933%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.4105%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.6029%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 5.4202%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.8977%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eALST (kg)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e20.7 (4.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e19.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e22.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e16.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e12.6\u0026ndash;32.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e14.6 (2.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e14.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e15.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e6.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e9.2\u0026ndash;22.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eFat mass (kg)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e21.7 (6.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e19.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e24.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e47.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e7.7\u0026ndash;33.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e27.9 (7.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e26.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e29.6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e51.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e13.6\u0026ndash;47.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eBone mineral content\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e2.6 (0.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e2.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e2.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e1.4\u0026ndash;3.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e2.0 (0.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e1.9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e2.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e0.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e1.4\u0026ndash;3.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 13.9464%;\"\u003e\n \u003cp\u003eResidual mass\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e22.8 (3.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e21.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e24.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e15.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e15.8\u0026ndash;36.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 4.933%;\"\u003e\n \u003cp\u003e18.5 (2.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e17.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.4105%;\"\u003e\n \u003cp\u003e19.2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.6029%;\"\u003e\n \u003cp\u003e8.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 5.4202%;\"\u003e\n \u003cp\u003e12.7\u0026ndash;27.7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"char\" style=\"width: 3.8977%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003ctfoot\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"12\" style=\"width: 64.19%;\"\u003eCI: confidence interval; SD: standard deviation; UL: upper limit; IL: inferior limit; Min-Max: minimum-maximum; ALST: appendicular lean soft tissue.\u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tfoot\u003e\n \u003c/table\u003e\n\u003c/div\u003e\n\u003cdiv class=\"gridtable\"\u003e\n \u003cdiv align=\"left\" class=\"colspec\"\u003eThe Kaiser-Meyer-Olkin test showed the sample adequacy and resulted in a value of 0.885, classified as meritorious (\u003cspan class=\"CitationRef\"\u003e62\u003c/span\u003e) and the Barlett sphericity test yielded a \u0026Chi;\u003csup\u003e2\u003c/sup\u003e of 3368.04 (p\u0026thinsp;\u0026lt;\u0026thinsp;0.001), indicating homogeneous variance between groups. From the univariate regression (stepwise), the number of remaining variables to ALST (n\u0026thinsp;=\u0026thinsp;08), FM (n\u0026thinsp;=\u0026thinsp;05) and BMC (n\u0026thinsp;=\u0026thinsp;06) showed high r\u003csup\u003e2\u003c/sup\u003e\u003csub\u003eadj\u003c/sub\u003e (0.68 to 0.88) for the independent common variables for the three dependents variables (Table \u003cspan class=\"InternalRef\"\u003e2\u003c/span\u003e). In bold, variables with statistically significant coefficients (p\u0026thinsp;\u0026lt;\u0026thinsp;0.05), common in at least two of the dependent variables are shown.\u003c/div\u003e\u0026nbsp;\u003ctable border=\"1\" id=\"Tab2\"\u003e\n \u003ccaption language=\"En\"\u003e\n \u003cdiv class=\"CaptionNumber\"\u003eTable 2\u003c/div\u003e\n \u003cdiv class=\"CaptionContent\"\u003e\n \u003cp\u003eUnivariate regression for selecting common independent variables at least twice (bold).\u003c/p\u003e\n \u003c/div\u003e\n \u003c/caption\u003e\n \u003ccolgroup cols=\"12\"\u003e\u003c/colgroup\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth align=\"left\" colspan=\"3\" style=\"width: 15.2685%;\"\u003e\n \u003cp\u003eAppendicular lean soft tissue\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" colspan=\"4\" style=\"width: 15.0788%;\"\u003e\n \u003cp\u003eFat mass\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\" colspan=\"3\" style=\"width: 18.3981%;\"\u003e\n \u003cp\u003eBone mineral content\u003c/p\u003e\n \u003c/th\u003e\n \u003c/tr\u003e\n \u003c/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eVariables\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCoefficient\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003ep\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eVariables\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.785%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCoefficient\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.9399%;\"\u003e\n \u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003ep\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eVariables\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCoefficient\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003ep\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePectoral skinfold (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.13018\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\n \u003cp\u003eMedia axillary skinfold (mm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\n \u003cp\u003e0.16083\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\n \u003cp\u003e0.012\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003eBi-styloid breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.210010\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.020\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWeight (kg)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.13214\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePectoral skinfold (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\n \u003cp\u003e-0.24240\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003eWaist circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e-0.030637\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003eKnee height (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.23779\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.009\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMedia thigh skinfold (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\n \u003cp\u003e0.12626\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\n \u003cp\u003e0.008\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTriceps skinfold (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e-0.020330\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003eBi-acromial breadth (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.30532\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWeight (kg)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\n \u003cp\u003e0.35620\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWeight (kg)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.038668\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eBiepicondylar humerus breadth (cm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e1.22979\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eHalf arm span (cm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\n \u003cp\u003e-0.29770\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\n \u003cp\u003e0.002\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eHalf arm span (cm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.032912\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.005\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003eCalf circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e0.26318\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003eMedial thigh circumference (cm)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e-0.028782\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMedia thigh skinfold (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e-0.07881\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTriceps skinfold (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\n \u003cp\u003e-0.09662\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\n \u003cp\u003e0.003\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" style=\"width: 8.4404%;\"\u003e\n \u003cp\u003eR\u003csup\u003e2\u003c/sup\u003e\u0026thinsp;=\u0026thinsp;0.88\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 6.3066%;\"\u003e\n \u003cp\u003eR\u003csup\u003e2\u003c/sup\u003e\u0026thinsp;=\u0026thinsp;0.85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 3.6512%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" colspan=\"2\" style=\"width: 5.0737%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 11.5225%;\"\u003e\n \u003cp\u003eR\u003csup\u003e2\u003c/sup\u003e\u0026thinsp;=\u0026thinsp;0.68\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 4.5047%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\" style=\"width: 2.3709%;\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003ctfoot\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"10\" style=\"width: 49.9783%;\"\u003eR\u003csup\u003e2\u003c/sup\u003e: coefficient of determination.\u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tfoot\u003e\n \u003c/table\u003e\n\u003c/div\u003e\n\u003cp\u003eNext, a multivariate linear regression model was developed, simultaneously for the three dependent variables from variables selected in the univariate models. The categorical sex variable has not been previously tested in the models; however, it was added to the multivariate procedure due to its theoretical relevance, as demonstrated by their significant comparisons in Table \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003e. The coefficients, variance inflation factor (VIF), Pillai\u0026rsquo;s trace, and precision and cross-validation results are shown in Table\u0026nbsp;3.\u003c/p\u003e\n\u003cp\u003eTable 3. Coefficients, precision, and validation of a multicomponent anthropometric model to estimate body composition in older adults.\u003c/p\u003e\n\u003cdiv class=\"gridtable\"\u003e\u0026nbsp;\u003ctable border=\"1\" id=\"Taba\"\u003e\n \u003ccolgroup cols=\"7\"\u003e\u003c/colgroup\u003e\n \u003cthead\u003e\n \u003ctr\u003e\n \u003cth align=\"left\"\u003e\u0026nbsp;\u003c/th\u003e\n \u003cth align=\"left\"\u003e\n \u003cp\u003eAppendicular lean soft tissue\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\"\u003e\n \u003cp\u003eFat mass\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\"\u003e\n \u003cp\u003eBone mineral content\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\"\u003e\n \u003cp\u003eVIF\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\"\u003e\n \u003cp\u003eF\u003c/p\u003e\n \u003c/th\u003e\n \u003cth align=\"left\"\u003e\n \u003cp\u003e\u003cem\u003ep\u003c/em\u003e (Pillai\u0026apos;s trace)\u003c/p\u003e\n \u003c/th\u003e\n \u003c/tr\u003e\n \u003c/thead\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003eCoefficients\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eIntercept\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e-10.21376\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e17.85412\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e-1.21230\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eWeight\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.19336\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.50239\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.01912\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e2.045\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e676.33\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eHalf arm span\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.20139\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e-0.40498\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.02944\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e2.049\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e9.53\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eTriceps skinfold\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e-0.04796\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.17292\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e-0.01267\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e2.544\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e4.17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.008\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eSex\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e-3.16675\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e4.73524\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e-0.13021\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e2.407\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e11.33\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e\u0026lt;\u0026thinsp;0.001\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003ePrecision\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eR\u003csup\u003e2\u003c/sup\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.83\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.62\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eR\u003csup\u003e2\u003c/sup\u003e\u003csub\u003eadjusted\u003c/sub\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.83\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.61\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eSEE\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e1.65\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e3.16\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.30\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\" colspan=\"2\"\u003e\n \u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003eCross-validation\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003ePRESS\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e287.00\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e1066.84\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e9.75\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eQ\u003csup\u003e2\u003c/sup\u003e\u003csub\u003ePRESS\u003c/sub\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.84\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.81\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.58\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003eSEE\u003csub\u003ePRESS\u003c/sub\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.18\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.34\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\n \u003cp\u003e0.03\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003ctd align=\"left\"\u003e\u0026nbsp;\u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003ctfoot\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\"\u003eR\u003csup\u003e2\u003c/sup\u003e: coefficient of determination; R\u003csup\u003e2\u003c/sup\u003e\u003csub\u003eadjusted\u003c/sub\u003e: adjusted coefficient of determination; SEE: standard error to estimate; PRESS: sum of squares of\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\"\u003eresiduals; Q\u003csup\u003e2\u003c/sup\u003e\u003csub\u003ePRESS\u003c/sub\u003e: press coefficient of determination; SEE\u003csub\u003ePRESS\u003c/sub\u003e: press standard error of estimate; VIF: variance inflation factor; Sex: male\u0026thinsp;=\u0026thinsp;0; female\u0026thinsp;=\u0026thinsp;1.\u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tfoot\u003e\n \u003c/table\u003e\n\u003c/div\u003e\n\u003cp\u003eHigher precision and cross-validation values of PRESS, Q\u003csup\u003e2\u003c/sup\u003e\u003csub\u003ePRESS,\u003c/sub\u003e and low SEE\u003csub\u003ePRESS\u003c/sub\u003e were found for each dependent variable (Table 3). These results showed that the models are valid to simultaneously predict ALST, FM, and BMC, with accordance close to \u0026ldquo;1\u0026rdquo; (Q\u003csup\u003e2\u003c/sup\u003e\u003csub\u003ePRESS\u003c/sub\u003e) and error close to \u0026ldquo;0\u0026rdquo; (S\u003csub\u003ePRESS\u003c/sub\u003e).\u003c/p\u003e\n\u003cp\u003eThe model standardized residuals are normally distributed (p\u0026thinsp;=\u0026thinsp;0.099) according to Fig. \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003e.\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003e \u003cdiv class=\"BlockQuote\"\u003e \u003cp\u003eTo the best of our knowledge, this is the first study that proposes a valid anthropometric model to simultaneously estimate FM, ALST, and BMC in older adults from a multicompartmental approach. DXA was used as a reference method due to its advantages in estimating all components by a single scan (\u003cspan citationid=\"CR63\" class=\"CitationRef\"\u003e63\u003c/span\u003e). Our proposed model with three anthropometric variables plus sex showed high prediction coefficients and low errors to simultaneously predict ALST, FM, and BMC. Since the BC is affected by sex (\u003cspan citationid=\"CR64\" class=\"CitationRef\"\u003e64\u003c/span\u003e), and changes in BC due to aging occur differently between men and women (\u003cspan citationid=\"CR65\" class=\"CitationRef\"\u003e65\u003c/span\u003e), the inclusion of the variable sex was made arbitrarily in the models generated in this study. Therefore, the current prediction equations are useful for estimating and monitoring ALST, FM, and BMC in older adults of both sexes.\u003c/p\u003e \u003cp\u003eCurrent anthropometric models to estimate BC in older adults have several limitations, causing errors in the estimation of BC. Furthermore, they have been developed using a bi-compartmental model (2-C) that determines FM and FFM (\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e, \u003cspan citationid=\"CR28\" class=\"CitationRef\"\u003e28\u003c/span\u003e, \u003cspan citationid=\"CR66\" class=\"CitationRef\"\u003e66\u003c/span\u003e), and this model is based on there is a linear relationship between subcutaneous fat, total fat, and BD. However, this is not true, because during the aging process there is age-related adipose tissue redistribution that is, an accumulation of visceral and abdominal fat occurs (\u003cspan citationid=\"CR67\" class=\"CitationRef\"\u003e67\u003c/span\u003e). Additionally, these equations do not evaluate ALST and BMC which are components that change during aging. The Lean equations (68) to estimate % body fat showed a coefficient of determination (r\u003csup\u003e2\u003c/sup\u003e) of 0.77 and 0.70 and standard error of estimate (SEE) of 4.1% and 4.7% for older adults men and women, respectively. However, our results for FM determination showed higher coefficient of determination (r\u003csup\u003e2\u003c/sup\u003e\u0026thinsp;=\u0026thinsp;0.83) and lower errors (SEE\u0026thinsp;=\u0026thinsp;3,16 kg).\u003c/p\u003e \u003cp\u003eProgressive and metabolically unfavorable changes in BC have long been observed with aging (\u003cspan citationid=\"CR69\" class=\"CitationRef\"\u003e69\u003c/span\u003e). In a prospective study that investigated age-dependent changes over two decades, the main results found were an increase in BM, BMI, and FM until the age of approximately 70 and 75 years, after these parameters start to decrease (\u003cspan citationid=\"CR70\" class=\"CitationRef\"\u003e70\u003c/span\u003e). Regarding the changes in the SMM, the studies have shown a greater reduction in men than in women, with a more accentuated decline between 70 and 79 years old in both sexes (\u003cspan citationid=\"CR56\" class=\"CitationRef\"\u003e56\u003c/span\u003e, \u003cspan citationid=\"CR69\" class=\"CitationRef\"\u003e69\u003c/span\u003e). However, the pattern and rate of age-related changes in BC may vary by sex, ethnicity, physical activity level, and caloric intake (\u003cspan citationid=\"CR71\" class=\"CitationRef\"\u003e71\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eDXA is the most popular technique for measuring BC (\u003cspan citationid=\"CR42\" class=\"CitationRef\"\u003e42\u003c/span\u003e) and it has shown to be a reliable method of FFM during aging (\u003cspan citationid=\"CR72\" class=\"CitationRef\"\u003e72\u003c/span\u003e). Furthermore, DXA may be considered the current reference technique for assessing SMM and BC in research and clinical practice (\u003cspan citationid=\"CR42\" class=\"CitationRef\"\u003e42\u003c/span\u003e). A high correlation (r\u0026thinsp;=\u0026thinsp;0.97) between DXA-measured ALST and SMM measured by magnetic resonance imaging (MRI) was reported for both men and women (18\u0026ndash;92 years) (\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e). In the same way, DXA-derived LST was found to be significantly correlated with MRI-measured SMM (r\u0026thinsp;=\u0026thinsp;0.94; p\u0026thinsp;\u0026le;\u0026thinsp;0.001) in older women (\u003cspan citationid=\"CR73\" class=\"CitationRef\"\u003e73\u003c/span\u003e). In comparisons between DXA-measured FM and MRI-measured adipose tissue the associations were also high and significant ( r\u0026thinsp;=\u0026thinsp;0.99; p\u0026thinsp;\u0026le;\u0026thinsp;0.001) for older women (\u003cspan citationid=\"CR73\" class=\"CitationRef\"\u003e73\u003c/span\u003e). The principle of DXA depends on the property of X-rays to be attenuated in proportion to the composition and depth of the material the beam is crossed. The DXA scanner emits two different energy beams (40 and 70 keV). From the number of photons that are transmitted concerning the number detected the quantity of BMC and soft tissue (fat and FFM) can be determined (\u003cspan citationid=\"CR42\" class=\"CitationRef\"\u003e42\u003c/span\u003e). Therefore, DXA can be used as a reference method to propose equations using anthropometry for clinical and professional practice (\u003cspan citationid=\"CR74\" class=\"CitationRef\"\u003e74\u003c/span\u003e). The anthropometric measurements are performed in both the geriatric nutritional assessment and epidemiological studies because they are painless, safe, non-invasive, simple, and low-cost procedures, which permit the estimation of the body components and also the calculation of nutritional indicators using predictive equations (\u003cspan citationid=\"CR32\" class=\"CitationRef\"\u003e32\u003c/span\u003e). The main anthropometric measurements used in the older adults for this purpose are weight, height, the calf and waist circumferences, as well as the triceps, biceps, subscapular and suprailiac skinfolds (32).\u003c/p\u003e \u003cp\u003eThe current investigation has several strengths. As far as we know, this is the first study that proposes equations to estimate the main components of BC from the same anthropometric variables for older adults. This implies a reduction in the prediction error and facilitates its use in epidemiological studies. Another positive point is that we included the variable sex in the generated models, facilitating the application in large groups of both sexes. Despite all the research efforts in this study, there were still some limitations: for example, DXA is not a gold standard for older adults\u0026rsquo; body composition. However, the current state-of-the-art method for body composition measurement in the four compartments model (4-C models) at the molecular level, as it includes the evaluation of the main FFM components, thus reducing the effect of biological variability. Nonetheless, it requires sophisticated and highly specialized technical equipment; it implies the propagation of measurement errors, difficult to apply in certain population groups, and is time-consuming. Furthermore, it has high costs, making it difficult to use on large samples (\u003cspan citationid=\"CR75\" class=\"CitationRef\"\u003e75\u003c/span\u003e). Nevertheless, DXA represents a reference method for the assessment of human BC in the research field (\u003cspan citationid=\"CR63\" class=\"CitationRef\"\u003e63\u003c/span\u003e, \u003cspan citationid=\"CR76\" class=\"CitationRef\"\u003e76\u003c/span\u003e) and it is widely considered the gold standard for BC assessment in clinical practice because of its advantages (\u003cspan citationid=\"CR74\" class=\"CitationRef\"\u003e74\u003c/span\u003e). Moreover, reference values of BC assessed by DXA on adults over 60 years old are available from the National Health and Nutrition Examination Survey 1999\u0026ndash;2004 and other studies on the local population (\u003cspan citationid=\"CR77\" class=\"CitationRef\"\u003e77\u003c/span\u003e). Although it is a program designed to assess the health of adults and children in the United States, these reference values should be helpful in the evaluation of a variety of adult abnormalities involving fat, LST, and bone.\u003c/p\u003e \u003cp\u003eAs it was hypothesized, using a multivariate regression model, simple anthropometric measures can be used to simultaneously estimate body components (ALST, FM, and BMC) in older adults of both sexes. As a practical simulation, an older adult male \u0026ldquo;A\u0026rdquo; with measurements of weight (66.3 kg), HAS (80.5 cm), TrSk (16 mm), and sex (0), when applied to our model, would have the estimated values of 18.1 kg, 21.3 kg and 2.2 kg for ALST, FM, and BMC, respectively. Their true measured values (DXA) were 18.2 kg, 20.8 kg, and 2.2 kg. If the equation is applied to an older adult woman \u0026ldquo;B\u0026rdquo; with values of weight (58.6 kg), HAS (81.5 cm), TriSK (26 mm), and sex (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e) the estimated values for ALST, FM, and BMC would be: 13.1 kg, 23.5 kg and 1.9 kg, correspondingly. As noted, the values are close to the measured DXA values for ALST (13.2 kg), FM (23.4 kg), and BMC (2.0 kg). These values can be compared with the reference values National Health and Nutrition Examination Survey (NHANES) (\u003cspan citationid=\"CR77\" class=\"CitationRef\"\u003e77\u003c/span\u003e) and be useful for many applications in clinical and field practice. For example, using the criteria proposed by the FNIH (cutoffs\u0026thinsp;\u0026lt;\u0026thinsp;19.75 for men and \u0026lt;\u0026thinsp;15.02 for women) we can classify both older adults with sarcopenia (\u003cspan citationid=\"CR78\" class=\"CitationRef\"\u003e78\u003c/span\u003e). Since older adult \u0026ldquo;A\u0026rdquo; presented predicted ALST values of 18.1 kg and older adult B of 13.1 kg. These findings are highly relevant as they allow permanent following/monitoring of excessive accumulation of FM, declines in BMC and ALST, as risks to older adults throughout the life course (\u003cspan citationid=\"CR79\" class=\"CitationRef\"\u003e79\u003c/span\u003e, \u003cspan citationid=\"CR80\" class=\"CitationRef\"\u003e80\u003c/span\u003e). Thus, keeping the balance rate of fat, muscle and bone are essential to preserving metabolic homeostasis, and health status and positively contributes to successful aging (\u003cspan citationid=\"CR74\" class=\"CitationRef\"\u003e74\u003c/span\u003e). For this reason, the assessment of BC in older adults is critical and could be an additional preventive strategy for age-related diseases (\u003cspan citationid=\"CR74\" class=\"CitationRef\"\u003e74\u003c/span\u003e), which may result in sarcopenia (\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e, \u003cspan citationid=\"CR48\" class=\"CitationRef\"\u003e48\u003c/span\u003e, \u003cspan citationid=\"CR81\" class=\"CitationRef\"\u003e81\u003c/span\u003e), osteoporosis (\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e) sarcopenic obesity (\u003cspan citationid=\"CR64\" class=\"CitationRef\"\u003e64\u003c/span\u003e) osteosarcopenic obesity (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e) and osteosarcopenia (\u003cspan citationid=\"CR11\" class=\"CitationRef\"\u003e11\u003c/span\u003e). This should impair muscle strength, and functional capacity, as well as greater morbidity and mortality in older adults (\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e, \u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e). Therefore, the current prediction equations could increase the available options for the estimation of body composition in older adults. To ensure dissemination and accessibility, an assessment of the main body components based on our predictive models can be found in an excel file (Additional file 1) in the following link (\u003cspan class=\"ExternalRef\"\u003e\u003cspan class=\"RefSource\"\u003ehttp://posgraduacao.eerp.usp.br/files/Model_BodyComposition_OlderAdults.xlsx\u003c/span\u003e\u003cspan address=\"http://posgraduacao.eerp.usp.br/files/Model_BodyComposition_OlderAdults.xlsx\" targettype=\"URL\" class=\"RefTarget\"\u003e\u003c/span\u003e\u003c/span\u003e). Lastly, future studies should evaluate the efficiency of these equations applied in longitudinal and intervention studies.\u003c/p\u003e \u003c/div\u003e \u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003eOur findings demonstrated that the anthropometric prediction equations developed in this study provide a reliable, practical, and low-cost instrument to assess the components that most change during the aging process. These results suggest that the equations can be valid alternative and reliable information about BC in older adults since the internal validation method PRESS presented high internal validity, high coefficients of determination, and low prediction errors. \u003c/p\u003e\n"},{"header":"Abbreviations","content":"\u003cp\u003eBody composition (BC)\u003c/p\u003e\n\u003cp\u003eSkeletal muscle mass (SMM)\u003c/p\u003e\n\u003cp\u003eFat mass (FM)\u003c/p\u003e\n\u003cp\u003eFat-free mass (FFM)\u003c/p\u003e\n\u003cp\u003eBone mineral content (BMC)\u003c/p\u003e\n\u003cp\u003eLean soft tissue (LST)\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eAppendicular lean soft tissue (ALST)\u0026nbsp;\u003c/p\u003e\n\u003cp\u003ePredicted residual error sum of squares (PRESS)\u003c/p\u003e\n\u003cp\u003eHalf arm span (HAS)\u003c/p\u003e\n\u003cp\u003eTriceps skinfold (TriSK)\u003c/p\u003e\n\u003cp\u003eStandard error to estimate (SEE)\u003c/p\u003e\n\u003cp\u003eBody density (BD)\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eDual energy X-ray absorptiometry (DXA)\u003c/p\u003e\n\u003cp\u003eMagnetic resonance imaging (MRI)\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003eEthics approval and consent to participate.\u003c/p\u003e\n\u003cp\u003eThe study was approved by the Ethics Review Board at University Hospital, the University of S\u0026atilde;o Paulo at Ribeir\u0026atilde;o Preto College of Nursing (EERP/USP), Brazil, with CAAE number: 18416619.3.0000.5393, and written informed consent was obtained from all subjects. All methods were carried out following the Declaration of Helsinki.\u003c/p\u003e\n\u003cp\u003eConsent for publication\u003c/p\u003e\n\u003cp\u003eNot applicable\u003c/p\u003e\n\u003cp\u003eAvailability of data and materials\u003c/p\u003e\n\u003cp\u003eThe datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.\u003c/p\u003e\n\u003cp\u003eCompeting interests\u003c/p\u003e\n\u003cp\u003eThe authors declare that they have no competing interests.\u003c/p\u003e\n\u003cp\u003eFunding\u003c/p\u003e\n\u003cp\u003eThis study was financed in part by the Coordena\u0026ccedil;\u0026atilde;o de Aperfei\u0026ccedil;oamento de Pessoal de N\u0026iacute;vel Superior - Brasil (CAPES) - Finance Code 001. This\u0026nbsp;study\u0026nbsp;was supported by the National Council for Scientific and Technological Development (CNPq-Brazil) under Grant 142078/2019-0.\u003c/p\u003e\n\u003cp\u003eAuthor\u0026rsquo;s contributions\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eACRV: Conceptualization; data curation; formal analysis; methodology; writing-original draft. LV: formal analysis; methodology; PPA: Data curation; formal analysis; writing-original draft. APS: Data curation; formal analysis; writing-original draft. MFTJ: Data curation; formal analysis; writing-original draft. LSLS: Data curation; formal analysis; writing-original draft. TCA: Data curation; formal analysis; writing-original draft. EF: Supervision; writing reviews and editing. \u0026nbsp;JLGS: Supervision; writing reviews and editing. VRP: Supervision; writing reviews and editing. JM: Supervision; writing reviews and editing. DRLM: Conceptualization; supervision; writing-review and editing.\u003c/p\u003e\n\u003cp\u003eAcknowledgments\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;Jorge Mota, Jose Luis Garcia-Soidan e Vicente Romo-Perez were supported by IACObus-2021-2022 program.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\u003cli\u003e\u003cspan\u003eJiang Y, Zhang Y, Jin M, Gu Z, Pei Y, Meng P. Aged-Related Changes in Body Composition and Association between Body Composition with Bone Mass Density by Body Mass Index in Chinese Han Men over 50-year-old. PLoS One. 2015 Jun 19;10(6):e0130400. doi: \u003cspan class=\"ExternalRef\"\u003e\u003cspan class=\"RefSource\"\u003e10.1371/journal.pone.0130400\u003c/span\u003e\u003cspan address=\"10.1371/journal.pone.0130400\" targettype=\"DOI\" class=\"RefTarget\"\u003e\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/li\u003e \u003cli\u003e\u003cspan\u003eBanitalebi E, Ghahfarrokhi MM, Dehghan M. 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Erratum in: Lancet. 2019 Jun 29;393(10191):2590\u003c/span\u003e\u003c/li\u003e\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"bmc-geriatrics","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bgtc","sideBox":"Learn more about [BMC Geriatrics](http://bmcgeriatr.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bgtc/default.aspx","title":"BMC Geriatrics","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"aging, DXA, equation, fat mass, bone mineral content, ALST","lastPublishedDoi":"10.21203/rs.3.rs-1835649/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-1835649/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e During aging, changes occur in the proportions of muscle, fat, and bone. The body composition (BC) alterations have a great impact on health, quality of life, and functional capacity. Several equations to predict BC using anthropometric measurements have been developed from a bi-compartmental (2-C) approach that determines only fat mass (FM) and fat-free mass (FFM). However, these models have several limitations, when considering constant density, progressive bone demineralization, and changes in the hydration of the FFM, as typical changes during senescence. Thus, the main purpose of this study was to propose and validate a new multi-compartmental anthropometric model to predict fat, bone, and musculature components in older adults of both sexes.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e This cross-sectional study included 100 older adults of both sexes. To determine the dependent variables (fat mass [FM], bone mineral content [BMC], and appendicular lean soft tissue [ALST]) whole total and regional DXA body scans were performed. Twenty-nine anthropometric measures and sex were appointed as independent variables. Models were developed through multivariate linear regression. Finally, the predicted residual error sum of squares (PRESS) statistic was used to measure the effectiveness of the predicted value for each dependent variable.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eResults: \u003c/strong\u003eAn equation was developed to simultaneously predict FM, BMC, and ALST from only four variables: weight, half arm span (HAS), triceps skinfold (TriSK), and sex. This model showed high coefficients of determination and low estimation errors (FM: R\u003csup\u003e2\u003c/sup\u003e\u003csub\u003eadj\u003c/sub\u003e: 0.83 and SEE: 3.16; BMC: R\u003csup\u003e2\u003c/sup\u003e\u003csub\u003eadj\u003c/sub\u003e: 0.61 and SEE: 0.30; ALST: R\u003csup\u003e2\u003c/sup\u003e\u003csub\u003eadj\u003c/sub\u003e: 0.85 and SEE: 1.65). \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eConclusion: \u003c/strong\u003eThe equations provide a reliable, practical, and low-cost instrument to monitor changes in body components during the aging process. The internal cross-validation method PRESS presented sufficient reliability in the model as an inexpensive alternative for clinical field use.\u0026nbsp;\u003c/p\u003e","manuscriptTitle":"Multicompartment body composition analysis in older adults: a cross-sectional study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2022-07-12 17:32:11","doi":"10.21203/rs.3.rs-1835649/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Major revision","date":"2022-10-18T05:22:51+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2022-10-09T18:51:47+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"569d5601-a931-4271-a284-cb8c0fd9c42f","date":"2022-09-29T22:44:13+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2022-08-16T15:53:13+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"8d4a50c6-546c-4096-95de-ac0a0573e756","date":"2022-08-10T13:10:15+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"ec10e430-3f64-4166-9587-7ec92c4d1320","date":"2022-08-09T18:52:58+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2022-08-02T16:22:03+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2022-07-30T15:13:20+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2022-07-08T17:34:51+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2022-07-08T17:06:27+00:00","index":"","fulltext":""},{"type":"submitted","content":"BMC Geriatrics","date":"2022-07-07T14:02:17+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"bmc-geriatrics","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bgtc","sideBox":"Learn more about [BMC Geriatrics](http://bmcgeriatr.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bgtc/default.aspx","title":"BMC Geriatrics","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"24ce3523-308e-4dda-bb98-70e555c51d6a","owner":[],"postedDate":"July 12th, 2022","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[],"tags":[],"updatedAt":"2023-10-16T18:48:48+00:00","versionOfRecord":{"articleIdentity":"rs-1835649","link":"https://doi.org/10.1186/s12877-023-03752-1","journal":{"identity":"bmc-geriatrics","isVorOnly":false,"title":"BMC Geriatrics"},"publishedOn":"2023-02-09 18:44:17","publishedOnDateReadable":"February 9th, 2023"},"versionCreatedAt":"2022-07-12 17:32:11","video":"","vorDoi":"10.1186/s12877-023-03752-1","vorDoiUrl":"https://doi.org/10.1186/s12877-023-03752-1","workflowStages":[]},"version":"v1","identity":"rs-1835649","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-1835649","identity":"rs-1835649","version":["v1"]},"buildId":"7rjqhiLT3MXkJMwkYKINL","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}