TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF

1995
OA: closed
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A triazolylated tertiary amine compound or salt thereof was identified as having aromatase inhibitory activity, making it useful for treating endometriosis and other conditions.

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Abstract

A triazolylated tertiary amine compound represented by general formula (I) or a salt thereof, having an aromatase inhibitory activity and being useful for preventing and treating breast cancer, mastopathy, endometriosis, prostatomegaly, etc., wherein A represents a single bond, lower alkylene or carbonyl; B represents lower alkyl, aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; D represents aryl, a 5- or 6-membered heterocyclic group, or a bicyclic fused heterocyclic group; and E represents 4H-1,2,4-triazolyl, 1H-1,2,4-triazolyl or 1H-1,2,3-triazolyl.

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europepmc
last seen: 2026-07-31T06:09:14.520117+00:00