HIGH DISCRIMINATING POWER BIOMARKER DIAGNOSING

Lack of non-invasive method for diagnosis of endometriosis has weighed down efforts to control and study the aetiopathogenesis of the disease among women of reproductive age. The early detection of endometriosis is crucial for its ultimate control and prevention. In many cases endometriosis is not diagnosed and treated until the disease has established itself and caused pathological symptoms. A published poll revealed women have to wait an average of 11.7 years in USA and 8.0 years in UK [Hadfield R. et al. Hum Reprod. 1996; 11 : 878 - 80] to get a correct diagnosis after the initial onset of symptoms for endometriosis.The present invention concerns a system and a method of in vitro diagnosing which comprises processing of several biomarker variables obtainable from in vitro assaying of at least one fluid sample or at least one cell containing sample of said patient, whereby the assay system produces input signals into a signal processor corresponding with activity or presence of each biomarker in said sample and whereby the input signals are processed in the signal processor comprising a mathematical model that produce output signals that is predictive for the extent of endometriosis or the progress of endometriosis in the patient.