Primary amenorrhea due to sclerotic or “non-functional” endometrium: Case presentation and literature review

Primary amenorrhea is less common than secondary amenorrhea. It can be caused by various anatomical, genetic, or hormonal factors during the development of the reproductive organs. Congenital absence of the endometrium or sclerotic endometrium is a very rare cause of primary amenorrhea with only three cases previously reported in English literature. We describe a case of sclerotic or non-functional endometrium in the context of Mullerian abnormality and normal female karyotype 46 XX.