CRYSTALLINE FORM OF 6-HYDROXY -3-(4-[2-(PIPERIDIN -1-YL) ETHOXY] PHENOXY)-2 -(4-METHOXYPHENYL) BENZO[B] THIOPHENE HYDROCHLORIDE.
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This invention describes a novel crystalline hydrate of a specific benzo[b]thiophene hydrochloride derivative and its use for inhibiting endometriosis alongside other estrogen-deprivation-associated diseases.
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Abstract
The present invention is directed to a novel crystalline hydrate of 6-hydroxy -3-(4-[2-(piperidin-1 -yl) ethoxy]phenoxy) -2-(4-methoxyphenyl benzo[b] thiophene hydrochloride and uses for same, including inhibition of disease states associated with estrogen deprivation including cardiovascular disease, hyperlipidemia, and osteoporosis and inhibition of other pathological conditions such as endometriosis, uterine fibrosis, estrogen-dependent cancer (including breast and uterine cancer), prostate cancer, benign prostatic hyperplasia, CNS disorders including Alzheimer's disease, prevention of breast cancer, and up-regulating ChAT.
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- europepmc
- last seen: 2026-07-27T06:15:28.040536+00:00