Global, neuronal, and beta-cell specific deletion of insulin inhibitory receptor (incep-tor) improves glucose homeostasis in diet-induced obese mice
preprint
OA: gold
CC-BY-4.0
Abstract
Abstract Our data support the hypothesis that inhibition of inceptor to sensitize INSR/IGF1R action may be a promising pharmacological target in the context of diet-induced impairments of glucose homeostasis, with the potential to avoid 𝛽-cell failure and to slow diabetes progression.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00
- unpaywall
- last seen: 2026-05-21T02:00:01.467718+00:00
License: CC-BY-4.0