Exogenous HMGB1 promotes pancreatic cancer progression by supporting the crosstalk between tumor and myeloid-derived suppressor cell

WITHDRAWN: Exogenous HMGB1 promotes pancreatic cancer progression by supporting the crosstalk between tumor and myeloid-derived suppressor cell | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article WITHDRAWN: Exogenous HMGB1 promotes pancreatic cancer progression by supporting the crosstalk between tumor and myeloid-derived suppressor cell Faming Wang, Wei Wei, Tao San, Liqin Li, ning wang This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3886646/v2 This work is licensed under a CC BY 4.0 License Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Editorial Note The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author. Editorial notes are used to provide important context regarding the topic of a preprint or to alert readers to potential issues concerning that preprint or a downstream publication associated with it. For more information on editorial notes, see our Editorial Policies . Abstract The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author. Full Text The authors have withdrawn this preprint from Research Square. Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3886646","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":666656742,"identity":"5e5e847d-b12e-4890-b125-5cbd6ad13275","order_by":0,"name":"Faming Wang","email":"","orcid":"","institution":"Huzhou Central Hospital, Affiliated Huzhou Central Hospital, Zhejiang Chinese Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Faming","middleName":"","lastName":"Wang","suffix":""},{"id":666656743,"identity":"c3f37de4-11ee-4af3-a5f2-63da97780033","order_by":1,"name":"Wei Wei","email":"","orcid":"","institution":"Huzhou Central Hospital, Affiliated Huzhou Central Hospital, Zhejiang Chinese Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Wei","middleName":"","lastName":"Wei","suffix":""},{"id":666656744,"identity":"a4f97884-7870-48d7-a924-3bf9254d1913","order_by":2,"name":"Tao San","email":"","orcid":"","institution":"Huzhou Central Hospital","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Tao","middleName":"","lastName":"San","suffix":""},{"id":666656745,"identity":"43cdf205-0639-470f-9336-bddd44ae554f","order_by":3,"name":"Liqin Li","email":"","orcid":"","institution":"Huzhou Central Hospital, Affiliated Huzhou Central Hospital, Zhejiang Chinese Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Liqin","middleName":"","lastName":"Li","suffix":""},{"id":666656746,"identity":"417de372-2195-40e7-a5f5-3b1ebc9cb487","order_by":4,"name":"ning wang","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAz0lEQVRIiWNgGAWjYDAC5gOMjxkYDgBZjA0MDAXEaGFLYDaGamlsYDAgTgubNEQLyBpitBgc406rLvhzR05+dnP7gx8GDPL8YgcIaeHddnsGzzNjgzsHGxt7DBgMZ85OwK/F7H7vtts8EocTN0gkNjbwGDAkGNwmpAVoSzGPweHE+TMSGxv/EKuFmSfhcGLDjcTGZqJssT/Gu1ma58BhsF9myxhIEPaLZBvvxs88fw4DQ6z9wcc3FTby/NIEtCCABBJJkpZRMApGwSgYBZgAAMyRRw3cRvCeAAAAAElFTkSuQmCC","orcid":"","institution":"Huzhou Central Hospital, Affiliated Huzhou Central Hospital, Zhejiang Chinese Medical University","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"ning","middleName":"","lastName":"wang","suffix":""}],"badges":[],"createdAt":"2024-01-22 02:18:26","currentVersionCode":2,"declarations":"","doi":"10.21203/rs.3.rs-3886646/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-3886646/v2","draftVersion":[],"editorialEvents":[],"editorialNote":"The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.","failedWorkflow":false,"files":[{"id":113125900,"identity":"e366688b-469d-4f0a-924d-a37702575280","added_by":"auto","created_at":"2026-06-26 09:57:41","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":62264,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3886646/v2/eb4d9429-689d-4267-a92d-4098d688abf7.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"WITHDRAWN: Exogenous HMGB1 promotes pancreatic cancer progression by supporting the crosstalk between tumor and myeloid-derived suppressor cell","fulltext":[{"header":"Full Text","content":"The authors have withdrawn this preprint from Research Square."}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":true,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":true,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"","lastPublishedDoi":"10.21203/rs.3.rs-3886646/v2","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-3886646/v2","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.","manuscriptTitle":"WITHDRAWN: Exogenous HMGB1 promotes pancreatic cancer progression by supporting the crosstalk between tumor and myeloid-derived suppressor cell","msid":"","msnumber":"","nonDraftVersions":[{"code":2,"date":"2026-06-25 16:33:02","doi":"10.21203/rs.3.rs-3886646/v2","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}},{"code":1,"date":"2024-01-25 15:57:56","doi":"10.21203/rs.3.rs-3886646/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"f2063c00-78f6-46c0-8b0e-1321a0ce221a","owner":[],"postedDate":"June 25th, 2026","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2026-06-25T16:33:02+00:00","versionOfRecord":[],"versionCreatedAt":"2026-06-25 16:33:02","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v2","identity":"rs-3886646","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-3886646","identity":"rs-3886646","version":["v2"]},"buildId":"ehx78VzkSd0WSzXnipQa-","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}