Intrinsic capacity and readmission and other adverse outcomes in older hypertensive patients in China: a one-year follow up study

Qizhe Zhang, Shanshan Shen, Xujiao chen
2023 · doi:10.21203/rs.3.rs-2665835/v1
preprint OA: closed CC-BY-4.0
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Abstract

Background: The relationship between intrinsic capacity (IC) and adverse events in older adults has attracted concerns. However, it’s little known in hypertensive patients. Our study sought to assess the decline of IC and adverse events among older hypertensive patients in China. Methods: It’s an observational study. All patients completed the comprehensive geriatric assessment (CGA) through interview and physical examination. The impairment of IC was analyzed. Univariate and multivariate logistic regression analyses were performed to explore the relationship between IC at baseline and adverse outcomes. Results: : The study consisted of 971 hypertensive participants at baseline. And Patients in the IC impairment group were older and had lower BMI, hobbies, and education levels. IC impairment was a risk factor for readmission, frailty, and falls (OR, 95% CI=1.17(1.00-1.36), p = 0.046), (OR, 95% CI=2.04(1.78-2.34; P<0.001), (OR, 95% CI=1.38 (1.21-1.58; P<0.001). Meanwhile, the follow-up records showed that the number of patients who met the requirements of locomotion, cognition, vitality, psychological, and sensory of five IC domains was 60.11%, 39.66%, 45.91% 11.02%, and 76.36%. Among them, the sensory domain decreases most obviously, but the motor function domain does not. Conclusions: : IC impairment is common among hypertensive old inpatients in China. In the future, the evaluation and intervention of IC ought to be further carried out to improve the quality of life and reduce the incidence of adverse events.

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License: CC-BY-4.0