Irreversible inhibitors of tyrosine kinases

BRIDGES ALEXANDER JAMES, DENNY WILLIAM ALEXANDER, DOBRUSIN ELLEN MYRA, DOHERTY ANNETTE MARIAN, FRY DAVID WILLIAM, MCNAMARA DENNIS JOSEPH, SHOWALTER HOWARD DANIEL HOLLIS, SMAILL JEFFREY B, ZHOU HAIRONG
2003
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This patent describes irreversible tyrosine kinase inhibitors and methods for treating conditions including endometriosis, cancer, restenosis, atherosclerosis, and psoriasis.

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Abstract

The present invention provides compounds that are irreversible inhibitors of tyrosine kinases. Also provided is a method of treating cancer, restenosis, atherosclerosis, endometriosis, and psoriasis and a pharmaceutical composition that comprises a compound that is an irreversible inhibitor of tyrosine kinases.

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europepmc
last seen: 2026-08-03T06:10:56.557307+00:00