Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura

Ferdinando Maggioni, Maggioni F, Antonio Palmieri, Palmieri A, Michele Tropea, Tropea M, Zanchin G, Giorgio Zanchin
The journal of headache and pain · 2008 · doi:10.1007/s10194-008-0018-x · PMID:18265933 · PMC3476179
case-report OA: gold CC-BY-NC-4.0
📄 Open PDF View on PubMed View at publisher

Abstract

We present the case of 48-year-old woman suffering from migraine with aura (MA) since menarche. During her life the patient frequently presented catamenial MA attacks with an increasing frequency during pregnancy in particular in the second and third trimesters, and then during breast-feeding. Treatment with oral contraceptive (OC) for endometriosis and later with cyclophosphamide, methotrexate, fluorouracil (CMF) for breast cancer produced a higher number of attacks. Instead, she referred an improvement with gonadotropin releasing hormone agonist (GnRH-a) for the treatment of endometriosis and then with tamoxifen as hormonal therapy after mastectomy and chemotherapy for breast cancer. We highlight the importance of physiological hormonal modification and hormonal therapies on the course of MA.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Antineoplastic Agents, Hormonal Contraceptives, Oral, Hormonal Migraine with Aura Migraine with Aura Amitriptyline Amitriptyline Analgesics Analgesics Antineoplastic Agents, Hormonal Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols Breast Neoplasms Breast Neoplasms Contraceptives, Oral, Hormonal Cyclophosphamide Cyclophosphamide Endometriosis Endometriosis Female Flunarizine

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

References (15)

Source provenance

crossref
last seen: 2026-06-27T06:32:55.888103+00:00
europepmc
last seen: 2026-07-28T06:14:09.330459+00:00
pubmed
last seen: 2026-05-13T22:14:42.556217+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: CC-BY-NC-4.0 · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine