Growth tradeoffs produce complex microbial communities on a single limiting resource

Michael Manhart, Eugene I. Shakhnovich
2018 · doi:10.1101/266569
preprint OA: closed
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Abstract

The relationship between the dynamics of a community and its constituent pairwise interactions is a fundamental problem in ecology. Higher-order ecological effects beyond pairwise interactions may be key to complex ecosystems, but mechanisms to produce these effects remain poorly understood. Here we show that higher-order effects can arise from variation in multiple microbial growth traits, such as lag times and growth rates, on a single limiting resource with no other interactions. These effects produce a range of ecological phenomena: an unlimited number of strains can exhibit multi stability and neutral coexistence, potentially with a single keystone strain; strains that coexist in pairs do not coexist all together; and the champion of all pairwise competitions may not dominate in a mixed community. Since variation in multiple growth traits is ubiquitous in microbial populations due to pleiotropy and non-genetic variation, our results indicate these higher-order effects may also be widespread, especially in laboratory ecology and evolution experiments.

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