[Prospective clinical and sonographic assessment of uterine artery embolization as the treatment of symptomatic uterine leiomyomata]

Alonso AM, A M Alonso, Marret H, H. Marret, Herbreteau D, D Herbreteau, Perrotin F, F Perrotin, R Bouquin, Bouquin R, G Body, Body G
Gynecologie, obstetrique & fertilite · 2003 · doi:10.1016/s1297-9589(03)00004-3 · PMID:12718983
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Uterine artery embolization was an effective treatment for symptomatic uterine leiomyomata, reducing uterus and fibroid volume by 51% and 65% respectively with a 12.5% failure rate over 18.9 months.

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Abstract

OBJECTIVE: To evaluate the effectiveness of the uterine artery embolization as the treatment of symptomatic uterine leiomyomata. PATIENTS AND METHODS: Eighty-five women with symptoms caused by uterine leiomyomata underwent uterine artery embolization as an alternative to surgery from january 1997 to june 2000. The effectiveness of this method was evaluated by clinical and sonographic examination. RESULTS: The recession average was of 18.9 months. There were ten failures. We had immediate failures (n = 5) with a case of technical failure, one endometrium cancer, one adenomyosis, one larger subserosal leiomyomata and one parametrial leiomyomata. We had recurrences (n = 5) with the occurrence of new leiomyomatas (1 intramural and 3 submucosal) and an evolution of previous leiomyomata. The average volume reduction was 51% for the uterus and 65% for the main fibroid at one year follow-up. Minor complications occurred in 5%. Permanent amenorrhoea was observed for 3.75% of the women. Using cox model, no predictive factors of embolisation effectiveness were found. DISCUSSION AND CONCLUSION: In the treatment of symptomatic uterine leiomyoma, uterine artery embolization is an effective alternative to surgery. After one year and half, we had 12.5% of failures.

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Condition tags

adenomyosis

MeSH descriptors

Embolization, Therapeutic Leiomyoma Uterine Neoplasms Adult Aged Embolization, Therapeutic Endosonography Female Humans Leiomyoma Leiomyoma Middle Aged Prospective Studies Treatment Failure Treatment Outcome Uterine Neoplasms Uterine Neoplasms Uterus Uterus Uterus

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