40 minutes RT-qPCR Assay for Screening Spike N501Y and HV69-70del Mutations

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Cites (2)

• Molecular dynamic simulation reveals E484K mutation enhances spike RBD-ACE2 affinity and the combination of E484K, K417N and N501Y mutations (501Y.V2 variant) induces conformational change greater than N501Y mutant alone, potentially resulting in an escape mutant 2021
• The N501Y and K417N mutations in the spike protein of SARS-CoV-2 alter the interactions with both hACE2 and human derived antibody: A Free energy of perturbation study 2020

References (7)

• Molecular dynamic simulation reveals E484K mutation enhances spike RBD-ACE2 affinity and the combination of E484K, K417N and N501Y mutations (501Y.V2 variant) induces conformational change greater than N501Y mutant alone, potentially resulting in an escape mutant via crossref
• The N501Y and K417N mutations in the spike protein of SARS-CoV-2 alter the interactions with both hACE2 and human derived antibody: A Free energy of perturbation study via crossref
• doi:10.1038/s41401-020-0485-4 via crossref
• doi:10.7554/elife.61312.sa2 via crossref
• doi:10.1016/j.cell.2020.06.043 via crossref
• doi:10.1016/j.cell.2020.05.034 via crossref
• doi:10.1093/cid/ciab014 via crossref

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