Construction of a nomogram to predict overall survival for patients with lung large cell neuroendocrine carcinoma: analysis of the SEER database

Construction of a nomogram to predict overall survival for patients with lung large cell neuroendocrine carcinoma: analysis of the SEER database | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research article Construction of a nomogram to predict overall survival for patients with lung large cell neuroendocrine carcinoma: analysis of the SEER database Dong Han, Fei Gao, Nan Li, Hao Wang, Qi Fu This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-16158/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background Lung large cell neuroendocrine carcinoma (L-LCNEC) has a poor prognosis with lower survival rate than other NSCLC patients. The estimation of an individual survival rate is puzzling. The main purpose of this study was to establish a more accurate model to predict the prognosis of L-LCNEC. Methods Patients aged 18 years or older with L-LCNEC were identified from the Surveillance, Epidemiology and End Results (SEER) database from 2004 to 2015. Cox regression analysis was used to identify factors associated with survival time. The results were used to construct a nomogram to predict 1-year, and 3-year survival probability in L-LCNEC patients. Overall survival (OS) were compared between low risk group and high risk group by the Kaplan–Meier analysis. Results A total of 3216 patients were included in the study. We randomly divided all included patients into 7:3 training and validating groups. In multivariable analysis of training cohort, age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy were independent prognostic factors for OS. All these factors were incorporated to construct a nomogram, which was tested in the validating cohort. Conclusions we constructed a visual nomogram prognosis model, which had the potential to predict the 1-year and 3-year survival rate of L-LCNEC patients, and could be used as an assistant prediction tool in clinical practice. Oncology Cancer Biology Lung large cell neuroendocrine carcinoma (L-LCNEC) nomogram Overall survival SEER Figures Figure 1 Figure 2 Figure 3 Figure 4 Introduction Lung cancer is one of the malignant tumors with high incidence and mortality rate in the world [ 1 ]. Lung large cell neuroendocrine carcinoma (L-LCNEC) is a kind of rare and invasive non-small cell lung cancer. L-LCNEC, which is characterized by both morphological differentiation of neuroendocrine tumors and large cell lung cancer, belongs to highly malignant neuroendocrine tumor. L-LCNEC is reclassified into the category of neuroendocrine tumors(NETs) by 2015 World Health Organization Classification of Lung Tumors. L-LCNEC is identified as an independent solid tumor with clinical and biological characteristics similar to small cell lung cancers (SCLC) [ 2 ]. The incidence of L-LCNEC accounts for 15% of lung NET and 2.0% − 3.5% of the lung cancer resected cases [ 3 , 4 ]. Compared with other NSCLC histological types, L-LCNEC has a poor prognosis with lower survival rate than other NSCLC patients in the same period, even for patients with early stage disease or received surgery treatment [ 5 – 8 ]. There are several literatures about the prognosis of L-LCNEC, but they often came from small samples retrospective analysis. At present, there is no reliable predictor for the prognosis of L-LCNEC. Meanwhile, the independent prognostic factors of cancer can be screened according to the traditional Kaplan Meier method and cox proportional hazards model, but the survival prediction analysis can't predict the survival of an individual. The existing TNM staging can not fully integrate the clinical prognosis information of patients, so it is necessary to develop a new prognosis prediction model which can combined with TNM staging to predict the risk of death more accurately and reliably. At present, nomogram model has been widely used in tumor survival prediction research[ 9 , 10 ]. Compared with the traditional TNM staging, nomogram has integrated more individual characteristics, including personal information, disease stage, treatment method, etc., and it has gradually become a new type of prognosis evaluation tool [ 11 – 13 ]. Our large-scale, population-based prospective cohort study is the first attempt to establish a predictive nomogram for L-LCNEC for 1-year and 3-year survival probability. Methods Data Sources The data of this retrospective study came from Surveillance, Epidemiology and End Results database (SEER database), which is the authoritative cancer statistical database in the United States. SEER database records the incidence, mortality and disease status of millions of cancer patients. At present, the number of registration stations has been expanded to eighteen. Data from registries are submitted to NCI twice a year for classification, statistics and aggregation, and cancer information of the population covered is disseminated to the United States and the world. We obtained the clinical information of patients diagnosed as L-LCNEC from SEER database in 2004-2015 with reference number 14026-nov2018 using SEER*STAT 8.3.6 software. Inclusion and exclusion criteria We extracted the data of L-LCNEC patients registered from 2004 to 2015. Patients who met the following criteria were included in this study: (1) Adults aged 18 years or older; (2) Patients with pathologically confirmed L-LCNEC; (3) No history of other primary tumor. Patients with the following conditions were excluded from this study: (1) Patients with incomplete TNM stage (AJCC, 6th Edition) information registration required by the research; (2) Patients whose survival time was less than one month. Variables extracted from the SEER database included the following: Age at diagnosis, Year of diagnosis, Sex, Race recode, Marital status, Primary Site(Mainbronchus, Upper lobe, Middle lobe, Lower lobe, Overlapping lesion of lung) ,TNM stage, Grade, Surgical recode, Radiation recode, Chemotherapy recode, Survival months, Vital status recode. Statistical analysis We randomly divided all included patients into 7:3 training and validating groups. Multivariable Cox proportional hazards models were determined to evaluate independent prognostic factors in training groups. Multivariable Cox proportional hazards model was used to estimate theβregression coefficient for each of the selected prognostic predictors. The risk scores of the training cohort were generated by combining with β expression coefficient and individual information of each patient. Those whose riskscore higher than median value were defined as high-risk group, Those whose riskscore lower than or equal to the median value were classified as low-risk group. Nomogram prediction model was built to predict the prognosis of L-LCNEC patients individually. C-index and calibration curve were used to evaluate the accuracy of model. Predictive value of model was assessed with the area under the receive operator characteristic curve (AUROC) . The model is validated by validating groups. For better analysis, all variables are converted to categorical variables. Overall survival was defined as the time from the beginning of the diagnosis until death of any cause or until the last follow-up date. The survival analysis was performed using Kaplan-Meier curves with P value determined by Log-rank method. The Hazard’s ratio was determined by univariate and multivariate Cox proportional hazard model. All statistical tests were two-sided, and P -value < 0.05 was considered statistically significant. Univariate and multivariate Cox analysis were carried out using SPSS 19.0 software, other statistical analysis were conducted using R(version 3.6.0). Results Characteristics of patients According to the inclusion criteria, 3216 patients were included in this study. The average age at diagnosis was 66.17±10.45 years old. The median age was 67 years old (age ranging from 18 to 94), 1725 patients were males and 1491 patients were females, the ratio of males to females was 1.16:1. We randomly divided all included patients into 7:3 training and validating groups. 2252 patients were in the training cohort and 964 were in the validation cohort. The characteristics and treatment measures of patients are shown in Table 1. Independent prognostic factors in the training cohort In the training cohort, the clinical characteristics and treatment measures of patients were included in the univariable analysis to explore the factors that may influence overall survival(OS). All significant factors in the univariable analysis and the variables that may be related to OS were entered into the multivariable analysis based on the Cox regression. Multivariate analyses indicated that age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy were independent prognostic factors for OS. The univariable and multivariate analysis are shown in Table 2. Riskscore and survival state in the training cohort In the training cohort, there were 1143 low-risk groups and 1109 high-risk groups. The riskscore and survival status of low-risk groups and high-risk groups are shown in Figure 1A and Figure 1B. By the end of follow-up, the survival rate of low-risk group was 39.1%, while that of high-risk group was 9.5%. The median survival time of high-risk group was significantly shorter than low-risk group. (7 months vs 28 months, p=0.000, Figure 1C). Nomogram construction Significant independent factors based on the results of the multivariable analysis, including age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy were incorporated to establish the nomogram for predicting 1-year, and 3-year survival probability. In the nomogram model, different scores (range 0-100) were given on a points scale at the top of the nomogram by the vertical line of the selected variable. The total score could be accumulated by adding the scores of all variables, and then we could estimate the probability of 1-year and 3-year survival of an individual patient by the vertical line to the prediction line at the bottom of the nomogram(Figure2). Validation of the Nomogram It is demonstrated that Harrell’s C-index for the established nomogram to predict OS was 0.75 in the training cohort. Likewise, Harrell’s C-index for prediction of OS in the validation cohort was 0.76. ROC curve and AUC were used to evaluate the prediction ability of nomogram to patients with L-LCNEC for 1-year survival rate (AUC =0.815) and 3-year survival rate (AUC =0.838) in the training cohort(Figure 3A, 3B). In the validation cohort, it also showed a good prediction ability of 1-year survival rate (AUC =0.812) and 3-year survival rate (AUC =0.86) (Figure 3C, 3D). Calibration of the Nomogram The calibration plots showed a good agreement between the prediction and actual observations for 1-year survival and 3--year survival in the training and validation cohorts(Figure4A-4D). Discussion L-LCNEC is a rare subtype of lung cancer classification. According to the existing literature reports, the average age of L-LCNEC was 60 years old, most of those were male [ 14 ], which was similar to our results. The survival rate of L-LCNEC greatly varied due to the selected patients’ age, tumor stage or treatment difference[ 15 – 23 ]. Clinicians' prediction for the survival probability of L-LCNEC is often based on the large-population study, but the estimation of an individual survival rate is puzzling. Therefore, it is necessary to establish a more accurate model to predict the prognosis of L-LCNEC and provide more effective treatment measures for individuals. Based on a retrospective study of high-quality, population-based data, our study summarized the clinical characteristics of patients with L-LCNEC, analyzed the factors related to the prognosis and established a more reasonable and effective nomogram model for predicting survival rate of L-LCNEC. Our results indicated that the independent factors influencing the prognosis of L-LCNEC were age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy. Compared with patients under 60 years old, there was an increased risk of death in patients over 60 years old. Increased risk in elderly groups may be due to their poor physical function, intolerance or insensitivity to surgery, chemotherapy, radiotherapy or other treatment methods, as well as multiple diseases combination. In terms of gender, the prognosis of male patients was worse than female patients, which may be related to the factors such as more smoking phenomenon involved in male patients or their different body functions or characteristics from female. Similar to other tumors, TNM staging is an independent factor for the prognosis of L-LCNEC patients. Compared with stage I patients, the risk of death in stage II patients increased by 1.06 times, stage III patients increased by 1.35 times, and stage IV patients increased by 3.02 times, thus suggesting that with the tumor staging increase, the risk of death in patients also increased. The possible reason is that the patients' body function is worse and the more complications appear with the advanced tumor stage, they are unable to receive comprehensive treatment for tumors. There is no standard treatment method for L-LCNEC. Similar to other subtypes of lung cancer, combined therapy, including surgery, chemotherapy and radiotherapy, were taken. The beneficial effect of surgery on L-LCNEC patients has been reported in the previous literatures[ 24 , 25 ]. Surgical-predominant therapy should be the principle method for treating L-LCNEC patients with early stage presently. Our study indicated surgery was an independent factor affecting the prognosis of L-LCNEC. However, the effect of surgery on the prognosis of L-LCNEC patients was also related to the surgical method. Compared with the patients who did not undergo surgery treatment, the results showed that the mortality risk of patients received local tumor destruction was reduced by 29.4%, but there was no statistical significance (P = 0.729), while the mortality risk of those received sublobar resection, lobectomy and pneumonectomy was reduced by 47.1% (P = 0.000), 61.3% (P = 0.000), 61.2%(P = 0.000)respectively. Therefore, surgical treatment may not be limited to stage I L-LCNEC patients, but should be extended to resectable patients after adjuvant chemotherapy. Lobectomy or pneumonectomy could be conducted as soon as possible if the patient's physical condition allowed, because the cancer cells grow rapidly and patients may lose the chance of surgery within a few months. L-LCNEC is aggressive with high potential to metastasize and is easy to recur after operation, so it is not enough to effectively treat the disease by surgery alone. L-LCNEC patients treated by surgery alone were rarely cured even in the early stage [ 26 ], which urges more scholars to consider chemotherapy or radiotherapy [ 6 , 18 , 27 , 28 ]. Two retrospective analysis showed that compared with the patients with surgery alone, platinum-based neoadjuvant chemotherapy or postoperative adjuvant chemotherapy could prolong the recurrence time of tumor and significantly benefit the long-term survival for the patients with early stage [ 29 , 30 ]. Chemotherapy regimens for small cell lung cancer/non-small cell lung cancer were used in L-LCNEC treatment, but most of the data were came from single center, small sample or retrospective studies, and the results were controversial [ 7 , 31 , 32 ]. For patients with advanced L-LCNEC, chemotherapy could significantly improve overall survival [ 33 – 36 ]. Our study also showed that chemotherapy may have a survival advantage. Since SEER database does not contain records of chemotherapy regimens, the topic which chemotherapy is better for L-LCNEC patients was not involved in our study. Because of the low incidence, there were a few literatures on radiotherapy for L-LCNEC. Mackley believed that if gross residual disease was present after surgery, adjuvant radiation should be recommended, adjuvant radiotherapy could be beneficial to local control and reduced the risk of local recurrence [ 37 ]. Rieber conclued that patients with incomplete resection showed a survival benefit from adjuvant radiotherapy [ 38 ]. Our results also supported the prognostic benefits of radiotherapy. Through the establishment of nomogram, we could predict individualized prognosis according to their scores in order to select an appropriate treatment strategy for individuals. There were some limitations in our study: this was a retrospective study, our results are inevitable subject to selection bias. In addition, due to the limited clinical factors included in SEER database, this study did not analyze the possible factors related to the prognosis of the disease, such as smoking record, genes status, chemotherapy schemes, ect.. Therefore, it is necessary for a prospective evaluation for the nomogram in clinical application. Conclusion In this study, our analysis indicated that age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy were independent prognostic factors for overall survival of L-LCNEC patients. And on this basis, we constructed a visual nomogram prognosis model, which had the potential to predict the 1-year and 3-year survival rate of L-LCNEC patients, and could be used as an assistant prediction tool in clinical practice. Abbreviations L-LCNEC Lung large cell neuroendocrine carcinoma; NETs neuroendocrine tumors; SEER The Surveillance, Epidemiology and End Results; OS Overall survival; AJCC:American Joint Committee on Cancer; AUROC Area under the receive operator characteristic curve Declarations Acknowledgments: We would like to give special thanks to the efforts of the SEER tumor registry team. Authors’ contributions: (I) Conception and design: Dong Han, Qi Fu; (II) Data analysis and interpretation: All authors; (III) Manuscript writing: All authors; (IV) Final approval of manuscript: All authors. Funding: The research for this manuscript was not financially supported and none of the authors had any relevant financial relationships. Availability of data and materials: All analyzed data are publicly available at the SEER website ( http://www.seer . cancer.gov), and should be requested under the approval of the SEER Program administration. Ethics approval and consent to participate: This study used a general dataset from the Surveillance, Epidemiology, and End Results database built by a public health program, and therefore did not require institutional review board approval. Consent for publication: Not applicable. Competing interests: The authors declare that they have no competing interests. Author details Department of Oncology & Hematology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China; Graduate School, China Academy of Chinese Medical Sciences, Beijing, China References 1. Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin 2015;65:87-108. 2. Fasano M, Della Corte CM, Papaccio F, et al. Pulmonary Large-Cell Neuroendocrine Carcinoma: From Epidemiology to Therapy. J Thorac Oncol 2015;10:1133-41. 3. Travis WD. Advances in neuroendocrine lung tumors. Ann Oncol 2010;21 Suppl 7:vii65-71. 4. Gridelli C, Rossi A, Airoma G, et al. Treatment of pulmonary neuroendocrine tumours: state of the art and future developments. Cancer Treat Rev 2013;39:466-72. 5. Battafarano RJ, Fernandez FG, Ritter J, et al. Large cell neuroendocrine carcinoma: an aggressive form of non-small cell lung cancer. J Thorac Cardiovasc Surg 2005;130:166-72. 6. Sarkaria IS, Iyoda A, Roh MS, et al. Neoadjuvant and adjuvant chemotherapy in resected pulmonary large cell neuroendocrine carcinomas: a single institution experience. Ann Thorac Surg 2011;92:1180-6; discussion 6-7. 7. Naidoo J, Santos-Zabala ML, Iyriboz T, et al. Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes. Clin Lung Cancer 2016;17:e121-e9. 8. Filosso PL, Guerrera F, Evangelista A, et al. Adjuvant chemotherapy for large-cell neuroendocrine lung carcinoma: results from the European Society for Thoracic Surgeons Lung Neuroendocrine Tumours Retrospective Database. Eur J Cardiothorac Surg 2017;52:339-45. 9. Karakiewicz PI, Briganti A, Chun FK, et al. Multi-institutional validation of a new renal cancer-specific survival nomogram. J Clin Oncol 2007;25:1316-22. 10. Tang XR, Li YQ, Liang SB, et al. Development and validation of a gene expression-based signature to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma: a retrospective, multicentre, cohort study. Lancet Oncol 2018;19:382-93. 11. Mariani L, Miceli R, Kattan MW, et al. Validation and adaptation of a nomogram for predicting the survival of patients with extremity soft tissue sarcoma using a three-grade system. Cancer 2005;103:402-8. 12. Sternberg CN. Are nomograms better than currently available stage groupings for bladder cancer? J Clin Oncol 2006;24:3819-20. 13. Wang L, Hricak H, Kattan MW, et al. Prediction of organ-confined prostate cancer: incremental value of MR imaging and MR spectroscopic imaging to staging nomograms. Radiology 2006;238:597-603. 14. Sanchez de Cos Escuin J. Diagnosis and treatment of neuroendocrine lung tumors. Arch Bronconeumol 2014;50:392-6. 15. Iyoda A, Hiroshima K, Moriya Y, et al. Postoperative recurrence and the role of adjuvant chemotherapy in patients with pulmonary large-cell neuroendocrine carcinoma. J Thorac Cardiovasc Surg 2009;138:446-53. 16. Glisson BS, Moran CA. Large-cell neuroendocrine carcinoma: controversies in diagnosis and treatment. J Natl Compr Canc Netw 2011;9:1122-9. 17. Varlotto JM, Medford-Davis LN, Recht A, et al. Should large cell neuroendocrine lung carcinoma be classified and treated as a small cell lung cancer or with other large cell carcinomas? J Thorac Oncol 2011;6:1050-8. 18. Fournel L, Falcoz PE, Alifano M, et al. Surgical management of pulmonary large cell neuroendocrine carcinomas: a 10-year experience. Eur J Cardiothorac Surg 2013;43:111-4. 19. Iyoda A, Jiang SX, Travis WD, et al. Clinicopathological features and the impact of the new TNM classification of malignant tumors in patients with pulmonary large cell neuroendocrine carcinoma. Mol Clin Oncol 2013;1:437-43. 20. Filosso PL, Ruffini E, Di Gangi S, et al. Prognostic factors in neuroendocrine tumours of the lung: a single-centre experience. Eur J Cardiothorac Surg 2014;45:521-6; discussion 6. 21. Sakurai H, Asamura H. Large-cell neuroendocrine carcinoma of the lung: surgical management. Thorac Surg Clin 2014;24:305-11. 22. Eichhorn F, Dienemann H, Muley T, et al. Predictors of survival after operation among patients with large cell neuroendocrine carcinoma of the lung. Ann Thorac Surg 2015;99:983-9. 23. Filosso PL, Rena O, Guerrera F, et al. Clinical management of atypical carcinoid and large-cell neuroendocrine carcinoma: a multicentre study on behalf of the European Association of Thoracic Surgeons (ESTS) Neuroendocrine Tumours of the Lung Working Groupdagger. Eur J Cardiothorac Surg 2015;48:55-64. 24. Roesel C, Terjung S, Weinreich G, et al. A Single-Institution Analysis of the Surgical Management of Pulmonary Large Cell Neuroendocrine Carcinomas. Ann Thorac Surg 2016;101:1909-14. 25. Mochizuki E, Matsuura S, Oishi K, et al. Surgical resection for clinical stage I high-grade neuroendocrine carcinoma of the lung. World J Surg Oncol 2018;16:33. 26. Saji H, Tsuboi M, Matsubayashi J, et al. Clinical response of large cell neuroendocrine carcinoma of the lung to perioperative adjuvant chemotherapy. Anticancer Drugs 2010;21:89-93. 27. Veronesi G, Morandi U, Alloisio M, et al. Large cell neuroendocrine carcinoma of the lung: a retrospective analysis of 144 surgical cases. Lung Cancer 2006;53:111-5. 28. Kim KW, Kim HK, Kim J, et al. Outcomes of Curative-Intent Surgery and Adjuvant Treatment for Pulmonary Large Cell Neuroendocrine Carcinoma. World J Surg 2017;41:1820-7. 29. Iyoda A, Hiroshima K, Toyozaki T, et al. Adjuvant chemotherapy for large cell carcinoma with neuroendocrine features. Cancer 2001;92:1108-12. 30. Kujtan L, Muthukumar V, Kennedy KF, et al. The Role of Systemic Therapy in the Management of Stage I Large Cell Neuroendocrine Carcinoma of the Lung. J Thorac Oncol 2018;13:707-14. 31. Sun JM, Ahn MJ, Ahn JS, et al. Chemotherapy for pulmonary large cell neuroendocrine carcinoma: similar to that for small cell lung cancer or non-small cell lung cancer? Lung Cancer 2012;77:365-70. 32. Derks JL, van Suylen RJ, Thunnissen E, et al. Chemotherapy for pulmonary large cell neuroendocrine carcinomas: does the regimen matter? Eur Respir J 2017;49. 33. Shimada Y, Niho S, Ishii G, et al. Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens. Lung Cancer 2012;75:368-73. 34. Le Treut J, Sault MC, Lena H, et al. Multicentre phase II study of cisplatin-etoposide chemotherapy for advanced large-cell neuroendocrine lung carcinoma: the GFPC 0302 study. Ann Oncol 2013;24:1548-52. 35. Niho S, Kenmotsu H, Sekine I, et al. Combination chemotherapy with irinotecan and cisplatin for large-cell neuroendocrine carcinoma of the lung: a multicenter phase II study. J Thorac Oncol 2013;8:980-4. 36. Tokito T, Kenmotsu H, Watanabe R, et al. Comparison of chemotherapeutic efficacy between LCNEC diagnosed using large specimens and possible LCNEC diagnosed using small biopsy specimens. Int J Clin Oncol 2014;19:63-7. 37. Mackley HB, Videtic GM. Primary carcinoid tumors of the lung: a role for radiotherapy. Oncology (Williston Park) 2006;20:1537-43; discussion 44-5, 49. 38. Rieber J, Schmitt J, Warth A, et al. Outcome and prognostic factors of multimodal therapy for pulmonary large-cell neuroendocrine carcinomas. Eur J Med Res 2015;20:64. Tables Table 1 Demographics and Clinical characteristics of patients Clinical parameters No. of Patients No. of training cohort No. of validation cohort Age at diagnosis <60 849（26.4%） 601（26.7%） 248（25.7%） ≥60 2367（73.6%） 1651（73.3%） 716（74.3%） Sex Male 1725（53.6%） 1198（53.2%） 527（54.7%） Female 1491（46.4%） 1054（46.8%） 437（45.3%） Race White 2702（84.0%） 1897（84.2%） 805（83.5%） Black 378（11.8%） 262（11.6%） 116（12.0%） Other 136（4.2%） 93（4.1%） 43（4.5%） Marital status at diagnosis Married 1722（53.5%） 1178（52.3%） 544（56.4%） Non-married 1494（46.5%） 1974（47.7%） 420（43.6%） Year of diagnosis 2004 174 (5.4%) 126 (5.6%) 48 (5.0%) 2005 183 (5.7%) 119 (5.3%) 64 (6.6%) 2006 228 (7.1%) 164 (7.3%) 64 (6.6%) 2007 242 (7.5%) 169 (7.5%) 73 (7.6%) 2008 235 (7.3%) 162 (7.2%) 73 (7.6%) 2009 278 (8.6%) 196 (8.7%) 82 (8.5%) 2010 294 (9.1%) 194 (8.6%) 100 (10.4%) 2011 274 (8.5%) 202 (9.0%) 72 (7.5%) 2012 319 (9.9%) 232 (10.3%) 87 (9.0%) 2013 347 (10.8%) 244 (10.8%) 103 (10.7%) 2014 332 (10.3%) 234 (10.4%) 98 (10.2%) 2015 310 (9.6%) 210 (9.3%) 100 (10.4%) Primary tumor Site Main bronchus 117（3.6%） 83（3.7%） 34（3.5%） Upper lobe 1762（54.8%） 1209（53.7%） 553（57.4%） Middle lobe 143（4.4） 106（4.7%） 37（3.8%） Lower lobe 773（24.0） 567（25.2%） 206（21.4%） Overlapping lesion 37（1.2%） 27（1.2%） 10（1.0%） NOS 384（11.9%） 260（11.5%） 124（12.9%） Grade Well differentiated 14（0.4%） 8（0.4%） 6（0.6%） Moderately differentiated 49（1.5%） 35（1.6%） 14（4.5%） Poorly differentiated 1166（36.3%） 825（36.6%） 341（35.4%） Undifferentiated; 386（12.0%） 270（12.0%） 116（12.0%） Unknown 1601（49.8%） 1114（49.5%） 487（50.5%） TNM I 903（28.1%） 641（28.5%） 262（27.2%） II 205（6.4%） 145（6.4%） 69（6.2%） III 690（21.5%） 483（21.4%） 207（21.5%） IV 1418（44.1%） 983（43.7%） 435（45.1%） Surgical therapy No 1931（60.0%） 1345（59.7%） 586（60.8%） Local tumor destruction 4（0.1%） 2（0.1%） 2（0.2%） Less than one lobe resection 325（10.1%） 235（10.4%） 90（9.3%） Lobectomy 851（26.5%） 595（25.4%） 256（26.6%） Pneumonectomy 105（3.3%） 75（3.3%） 30（3.1%） Radiotherapy No 1924（59.8%） 1332（59.1%） 592（61.4%） Yes 1292（40.2%） 920（40.9%） 372（38.6&） Chemotherapy No 1453（45.2%） 1022（45.4%） 431（44.7%） Yes 1763（54.8%） 1230（54.6%） 533（55.3%） Table2 Univariable analysis and Multivariable analysis of Training Cohort Parameters Univariable analysis Multivariable analysis HR 95%CI P HR 95%CI P Age at diagnosis <60 1.00（Ref） 1.00（Ref） ≥60 1.359 1.216-1.519 0.000 1.407 1.253-1.579 0.000 Sex Female 1.00（Ref） 1.00（Ref） Male 0.850 0.773-0.936 0.001 0.773 0.699-0.855 0.000 Race Black 1.00（Ref） 1.00（Ref） White 1.030 0.887-1.196 0.698 0.953 0.817-1.112 0.539 Other 1.068 0.843-1.353 0.586 0.991 0.779-1.260 0.939 Marital status at diagnosis Married 1.00（Ref） 1.00（Ref） Non-married 1.064 0.967-1.171 0.201 1.080 0.975-1.196 0.141 Year of diagnosis 2004 1.00（Ref） 1.00（Ref） 2005 1.204 0.919-1.577 0.179 1.179 0.896-1.550 0.240 2006 1.093 0.850-1.405 0.488 1.099 0.851-1.417 0.470 2007 1.193 0.928-1.533 0.169 0.956 0.740-1.234 0.729 2008 1.073 0.830-1.387 0.591 0.968 0.746-1.256 0.806 2009 1.154 0.903-1.477 0.253 1.068 0.831-1.374 0.606 2010 1.063 0.828-1.365 0.633 0.968 0.750-1.244 0.801 2011 1.285 1.003-1.645 0.047 1.179 0.917-1.516 0.200 2012 1.351 1.061-1.720 0.015 1.088 0.851-1.392 0.500 2013 1.198 0.937-1.533 0.149 1.073 0.836-1.377 0.582 2014 1.429 1.109-1.840 0.006 1.113 0.860-1.441 0.415 2015 1.317 0.959-1.810 0.089 1.159 0.839-1.599 0.371 Primary tumor Site Main bronchus 1.00（Ref） 1.00（Ref） Upper lobe 0.450 0.355-0.572 0.000 0.722 0.567-0.919 0.008 Middle lobe 0.511 0.374-0.698 0.000 0.897 0.654-1.232 0.503 Lower lobe 0.448 0.350-0.575 0.000 0.746 0.579-0.960 0.023 Overlapping lesion 0.635 0.388-1.041 0.072 0.740 0.449-1.220 0.238 NOS 0.824 0.634-1.071 0.148 0.655 0.502-0.855 0.002 Grade Well differentiated 1.00（Ref） 1.00（Ref） Moderately differentiated 0.757 0.285-2.007 0.575 0.933 0.349-2.495 0.890 Poorly differentiated 0.986 0.409-2.379 0.975 1.127 0.464-2.736 0.792 Undifferentiated; 1.125 0.463-2.734 0.749 1.279 0.523-3.128 0.590 Unknown 1.592 0.661-3.834 0.300 1.093 0.450-2.651 0.844 TNM I 1.00（Ref） 1.00（Ref） II 1.568 1.248-1.971 0.000 2.062 1.627-2.614 0.000 III 2.423 2.090-2.808 0.000 2.357 1.950-2.844 0.000 IV 4.098 4.305-5.597 0.000 4.021 3.329-4.856 0.000 Surgical therapy No 1.00（Ref） 1.00（Ref） Local tumor destruction 0.501 0.070-3.559 0.489 0.706 0.099-5.051 0.729 Less than one lobe resection 0.361 0.305-0.427 0.000 0.529 0.431-0.651 0.000 Lobectomy 0.247 0.217-0.281 0.000 0.387 0.322-0.465 0.000 Pneumonectomy 0.309 0.229-0.470 0.000 0.388 0.281-0.536 0.000 Radiotherapy No 1.00（Ref） 1.00（Ref） Yes 1.413 1.283-1.557 0.000 0.833 0.749-0.928 0.001 Chemotherapy No 1.00（Ref） 1.00（Ref） Yes 1.112 1.010-1.224 0.031 0.559 0.500-0.624 0.000 Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-16158","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research article","associatedPublications":[],"authors":[{"id":385098,"identity":"b7faa9cc-d79e-46d2-8783-ad56d899f405","order_by":1,"name":"Dong Han","email":"","orcid":"","institution":"Beijing Hospital of Traditional Chinese Medicine","correspondingAuthor":false,"prefix":"","firstName":"Dong","middleName":"","lastName":"Han","suffix":""},{"id":385099,"identity":"b6d7ac3c-d4e2-4d6d-bb0b-ac8efcdebdb2","order_by":2,"name":"Fei Gao","email":"","orcid":"","institution":"Chongqing City Hospital of Traditional Chinese Medicine","correspondingAuthor":false,"prefix":"","firstName":"Fei","middleName":"","lastName":"Gao","suffix":""},{"id":385100,"identity":"129b6655-e8a1-462e-a193-b519c9a2f3f2","order_by":3,"name":"Nan Li","email":"","orcid":"","institution":"China Academy of Chinese Medical Science","correspondingAuthor":false,"prefix":"","firstName":"Nan","middleName":"","lastName":"Li","suffix":""},{"id":385101,"identity":"aa9248af-35b7-442d-ad16-fcb79af9f7f9","order_by":4,"name":"Hao Wang","email":"","orcid":"","institution":"Beijing Hospital of Traditional Chinese Medicine","correspondingAuthor":false,"prefix":"","firstName":"Hao","middleName":"","lastName":"Wang","suffix":""},{"id":385102,"identity":"a36a7db1-d1a7-43a1-9f5f-01acaccf7289","order_by":5,"name":"Qi Fu","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAwUlEQVRIiWNgGAWjYBAC9gYGhgMgBj8z8+EHRGnhOQDVItnOlmZAtBYwMDjPoyBBnBaJ5I0Hf7YdTtx8mIfBgKHGJpoILWkFBySBWrYd5j3wgOFYWm4DIS32EjkGBwzBWvgSDBgbDhPWwgPSkghyWDOPgQTxWg4CtWxgJloLz7OCgw3n0o1nHAYGcgIxfuFhT9788UeZtWx//+HDDz7U2BDWAgQGDIxszY5glQlEKIdoYfhTZ0+k4lEwCkbBKBiJAABMEUR32RAzlgAAAABJRU5ErkJggg==","orcid":"","institution":"","correspondingAuthor":true,"prefix":"","firstName":"Qi","middleName":"","lastName":"Fu","suffix":""}],"badges":[],"createdAt":"2020-03-02 13:54:23","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-16158/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-16158/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":603881,"identity":"9d316d94-b1f7-46cf-800d-d123c89f79b7","added_by":"auto","created_at":"2020-03-05 22:03:41","extension":"jpg","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":479927,"visible":true,"origin":"","legend":"A: Patients ranked in the order of riskscore in the training cohort. The green line represents low risk groups, the red line represents high risk groups, the horizontal dotted line represents the value of median riskscore, low risk groups and high risk groups are separated by the vertical dotted line. B: The survival status of low risk groups and high risk groups. Low risk groups and high risk groups are separated by the vertical dotted line. Green dots represents survival status, red dots represents dead status. C: Overall survival of patients stratified by riskscore. Overall survival of high-risk group (n=1109) (HR=3.298, 95%CI=2.975-3.657, P=0.000) versus low-risk group (n=1143).","description":"","filename":"1.jpg","url":"https://assets-eu.researchsquare.com/files/rs-16158/v1/1.jpg"},{"id":603882,"identity":"b030a7a7-79d9-4055-b918-72f0127f7902","added_by":"auto","created_at":"2020-03-05 22:03:41","extension":"jpg","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":131513,"visible":true,"origin":"","legend":"Prognostic nomogram for patients with L-LCNEC. \n*0: No surgical treatment, 1: Local tumor destruction, 2: sublobar resection, 3: Lobectomy, 4: Pneumonectomy.\n#Yes: Received this treatment, No: Not received this treatment","description":"","filename":"2.jpg","url":"https://assets-eu.researchsquare.com/files/rs-16158/v1/2.jpg"},{"id":603883,"identity":"8bea616f-9fd5-4e2f-af29-b90709ecaece","added_by":"auto","created_at":"2020-03-05 22:03:41","extension":"jpg","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":265512,"visible":true,"origin":"","legend":"ROC curve for the prediction ability of nomogram to patients with L-LCNEC for (A) 1-year survival rate, (B) 3-year survival rate in the training cohort and for (C) 1-year survival rate, (D) 3-year survival rate in the validation cohort.","description":"","filename":"3.jpg","url":"https://assets-eu.researchsquare.com/files/rs-16158/v1/3.jpg"},{"id":603884,"identity":"cb61f301-dc70-4c9b-991b-368369c1876a","added_by":"auto","created_at":"2020-03-05 22:03:41","extension":"jpg","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":234198,"visible":true,"origin":"","legend":"The calibration curve for predicting patients survival at (A) 1-year, (B)3-year in the training cohort and at (C) 1-year , (D)3-year in the validation cohort. \nNomogram-predicted probability of survival is plotted on the x-axis, and actual survival is plotted on the y-axis.","description":"","filename":"4.jpg","url":"https://assets-eu.researchsquare.com/files/rs-16158/v1/4.jpg"},{"id":13492555,"identity":"fa0b1060-8dd5-4c5a-ac43-2bd72e574d0d","added_by":"auto","created_at":"2021-09-16 22:32:01","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":583993,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-16158/v1/9d7f86d9-6398-481c-a083-27c8103d26cd.pdf"}],"financialInterests":"","formattedTitle":"Construction of a nomogram to predict overall survival for patients with lung large cell neuroendocrine carcinoma: analysis of the SEER database","fulltext":[{"header":"Introduction","content":" \u003cp\u003eLung cancer is one of the malignant tumors with high incidence and mortality rate in the world [\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e]. Lung large cell neuroendocrine carcinoma (L-LCNEC) is a kind of rare and invasive non-small cell lung cancer. L-LCNEC, which is characterized by both morphological differentiation of neuroendocrine tumors and large cell lung cancer, belongs to highly malignant neuroendocrine tumor. L-LCNEC is reclassified into the category of neuroendocrine tumors(NETs) by 2015 World Health Organization Classification of Lung Tumors. L-LCNEC is identified as an independent solid tumor with clinical and biological characteristics similar to small cell lung cancers (SCLC) [\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e]. The incidence of L-LCNEC accounts for 15% of lung NET and 2.0% \u0026minus;\u0026thinsp;3.5% of the lung cancer resected cases [\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e, \u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eCompared with other NSCLC histological types, L-LCNEC has a poor prognosis with lower survival rate than other NSCLC patients in the same period, even for patients with early stage disease or received surgery treatment [\u003cspan additionalcitationids=\"CR6 CR7\" citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e]. There are several literatures about the prognosis of L-LCNEC, but they often came from small samples retrospective analysis. At present, there is no reliable predictor for the prognosis of L-LCNEC. Meanwhile, the independent prognostic factors of cancer can be screened according to the traditional Kaplan Meier method and cox proportional hazards model, but the survival prediction analysis can't predict the survival of an individual. The existing TNM staging can not fully integrate the clinical prognosis information of patients, so it is necessary to develop a new prognosis prediction model which can combined with TNM staging to predict the risk of death more accurately and reliably.\u003c/p\u003e \u003cp\u003eAt present, nomogram model has been widely used in tumor survival prediction research[\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e, \u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e]. Compared with the traditional TNM staging, nomogram has integrated more individual characteristics, including personal information, disease stage, treatment method, etc., and it has gradually become a new type of prognosis evaluation tool [\u003cspan additionalcitationids=\"CR12\" citationid=\"CR11\" class=\"CitationRef\"\u003e11\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e]. Our large-scale, population-based prospective cohort study is the first attempt to establish a predictive nomogram for L-LCNEC for 1-year and 3-year survival probability.\u003c/p\u003e "},{"header":"Methods","content":"\u003cp\u003e\u003cstrong\u003eData Sources\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe data of this retrospective study came from Surveillance, Epidemiology and End Results database (SEER database), which is the authoritative cancer statistical database in the United States. SEER database records the incidence, mortality and disease status of millions of cancer patients. At present, the number of registration stations has been expanded to eighteen. Data from registries are submitted to NCI twice a year for classification, statistics and aggregation, and cancer information of the population covered is disseminated to the United States and the world. We obtained the clinical information of patients diagnosed as L-LCNEC from SEER database in 2004-2015 with reference number 14026-nov2018 using SEER*STAT 8.3.6 software.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eInclusion and exclusion criteria \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWe extracted the data of L-LCNEC patients registered from 2004 to 2015. Patients who met the following criteria were included in this study: (1) Adults aged 18 years or older; (2) Patients with pathologically confirmed L-LCNEC; (3) No history of other primary tumor.\u003c/p\u003e\n\u003cp\u003ePatients with the following conditions were excluded from this study: (1) Patients with incomplete TNM stage (AJCC, 6th Edition) information registration required by the research; (2) Patients whose survival time was less than one month.\u003c/p\u003e\n\u003cp\u003eVariables extracted from the SEER database included the following: Age at diagnosis, Year of diagnosis, Sex, Race recode, Marital status, Primary Site(Mainbronchus, Upper lobe, Middle lobe, Lower lobe, Overlapping lesion of lung) ,TNM stage, Grade, Surgical recode, Radiation recode, Chemotherapy recode, Survival months, Vital status recode.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eStatistical analysis\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWe randomly divided all included patients into 7:3 training and validating groups. Multivariable Cox proportional hazards models were determined to evaluate independent prognostic factors in training groups. Multivariable Cox proportional hazards model was used to estimate the\u0026beta;regression coefficient for each of the selected prognostic predictors. The risk scores of the training cohort were generated by combining with \u0026beta; expression coefficient and individual information of each patient. Those whose riskscore higher than median value were defined as high-risk group, Those whose riskscore lower than or equal to the median value were classified as low-risk group.\u003c/p\u003e\n\u003cp\u003eNomogram prediction model was built to predict the prognosis of L-LCNEC patients individually. C-index and calibration curve were used to evaluate the accuracy of model. Predictive value of model was assessed with the area under\u0026nbsp;the\u0026nbsp;receive\u0026nbsp;operator\u0026nbsp;characteristic\u0026nbsp;curve (AUROC)\u0026nbsp;.\u003c/p\u003e\n\u003cp\u003eThe model is validated by validating groups. For better analysis, all variables are converted to categorical variables. Overall survival was defined as the time from the beginning of the diagnosis until death of any cause or until the last follow-up date. The survival analysis was performed using Kaplan-Meier curves with \u003cem\u003eP\u003c/em\u003e value determined by Log-rank method. The Hazard\u0026rsquo;s ratio was determined by univariate and multivariate Cox proportional hazard model. All statistical tests were two-sided, and \u003cem\u003eP\u003c/em\u003e-value \u0026lt; 0.05 was considered statistically significant. Univariate and multivariate Cox analysis were carried out using SPSS 19.0 software, other statistical analysis were conducted using R(version 3.6.0).\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003e\u003cstrong\u003eCharacteristics of patients \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAccording to the inclusion criteria, 3216 patients were included in this study. The average age at diagnosis was 66.17\u0026plusmn;10.45 years old. The median age was 67 years old (age ranging from 18 to 94), 1725 patients were males and 1491 patients were females, the ratio of males to females was 1.16:1. We randomly divided all included patients into 7:3 training and validating groups. 2252 patients were in the training cohort and 964 were in the validation cohort. The characteristics and treatment measures of patients are shown in Table 1.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eIndependent prognostic factors in the training cohort\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eIn the training cohort, the clinical characteristics and treatment measures of patients were included in the univariable analysis to explore the factors that may influence overall survival(OS). All significant factors in the univariable analysis and the variables that may be related to OS were entered into the multivariable analysis based on the Cox regression. Multivariate analyses indicated that age at diagnosis, sex, stage of tumor, surgical\u0026nbsp;treatment, radiotherapy and chemotherapy were independent prognostic factors for OS. The univariable and multivariate analysis are shown in Table 2.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eRiskscore and survival state in the training cohort \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eIn the training cohort, there were 1143 low-risk groups and 1109 high-risk groups. The riskscore and survival status of low-risk groups and high-risk groups are shown in Figure 1A and Figure 1B. By the end of follow-up, the survival rate of low-risk group was 39.1%, while that of high-risk group was 9.5%. The median survival time of high-risk group was significantly shorter than low-risk group. (7 months vs 28 months, p=0.000, Figure 1C).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eNomogram construction\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eSignificant independent factors based on the results of the multivariable analysis, including age at diagnosis, sex, stage of tumor, surgical\u0026nbsp;treatment, radiotherapy and chemotherapy were incorporated to establish the nomogram for predicting 1-year, and 3-year survival probability. In the nomogram model, different scores (range 0-100) were given on a points scale at the top of the nomogram by the vertical line of the selected variable. The total score could be accumulated by adding the scores of all variables, and then we could estimate the probability of 1-year and 3-year survival of an individual patient by the vertical line to the prediction line at the bottom of the nomogram(Figure2).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eValidation of the Nomogram\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eIt is demonstrated that Harrell\u0026rsquo;s C-index for the established nomogram to predict OS was 0.75 in the training cohort. Likewise, Harrell\u0026rsquo;s C-index for prediction of OS in the validation cohort was 0.76.\u003c/p\u003e\n\u003cp\u003eROC curve and AUC were used to evaluate the prediction ability of nomogram to patients with L-LCNEC for 1-year survival rate (AUC =0.815) and 3-year survival rate (AUC =0.838) in the training cohort(Figure 3A, 3B). In the validation cohort, it also showed a good prediction ability of 1-year survival rate (AUC =0.812) and 3-year survival rate (AUC =0.86) (Figure 3C, 3D).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCalibration of the Nomogram\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe calibration plots showed a good agreement between the prediction and actual observations for 1-year survival and 3--year survival in the training and validation cohorts(Figure4A-4D).\u003c/p\u003e"},{"header":"Discussion","content":" \u003cp\u003eL-LCNEC is a rare subtype of lung cancer classification. According to the existing literature reports, the average age of L-LCNEC was 60\u0026nbsp;years old, most of those were male [\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e], which was similar to our results. The survival rate of L-LCNEC greatly varied due to the selected patients\u0026rsquo; age, tumor stage or treatment difference[\u003cspan additionalcitationids=\"CR16 CR17 CR18 CR19 CR20 CR21 CR22\" citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e]. Clinicians' prediction for the survival probability of L-LCNEC is often based on the large-population study, but the estimation of an individual survival rate is puzzling. Therefore, it is necessary to establish a more accurate model to predict the prognosis of L-LCNEC and provide more effective treatment measures for individuals. Based on a retrospective study of high-quality, population-based data, our study summarized the clinical characteristics of patients with L-LCNEC, analyzed the factors related to the prognosis and established a more reasonable and effective nomogram model for predicting survival rate of L-LCNEC.\u003c/p\u003e \u003cp\u003eOur results indicated that the independent factors influencing the prognosis of L-LCNEC were age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy.\u003c/p\u003e \u003cp\u003eCompared with patients under 60\u0026nbsp;years old, there was an increased risk of death in patients over 60\u0026nbsp;years old. Increased risk in elderly groups may be due to their poor physical function, intolerance or insensitivity to surgery, chemotherapy, radiotherapy or other treatment methods, as well as multiple diseases combination. In terms of gender, the prognosis of male patients was worse than female patients, which may be related to the factors such as more smoking phenomenon involved in male patients or their different body functions or characteristics from female. Similar to other tumors, TNM staging is an independent factor for the prognosis of L-LCNEC patients. Compared with stage I patients, the risk of death in stage II patients increased by 1.06 times, stage III patients increased by 1.35 times, and stage IV patients increased by 3.02 times, thus suggesting that with the tumor staging increase, the risk of death in patients also increased. The possible reason is that the patients' body function is worse and the more complications appear with the advanced tumor stage, they are unable to receive comprehensive treatment for tumors.\u003c/p\u003e \u003cp\u003eThere is no standard treatment method for L-LCNEC. Similar to other subtypes of lung cancer, combined therapy, including surgery, chemotherapy and radiotherapy, were taken. The beneficial effect of surgery on L-LCNEC patients has been reported in the previous literatures[\u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e, \u003cspan citationid=\"CR25\" class=\"CitationRef\"\u003e25\u003c/span\u003e]. Surgical-predominant therapy should be the principle method for treating L-LCNEC patients with early stage presently. Our study indicated surgery was an independent factor affecting the prognosis of L-LCNEC. However, the effect of surgery on the prognosis of L-LCNEC patients was also related to the surgical method. Compared with the patients who did not undergo surgery treatment, the results showed that the mortality risk of patients received local tumor destruction was reduced by 29.4%, but there was no statistical significance (P\u0026thinsp;=\u0026thinsp;0.729), while the mortality risk of those received sublobar resection, lobectomy and pneumonectomy was reduced by 47.1% (P\u0026thinsp;=\u0026thinsp;0.000), 61.3% (P\u0026thinsp;=\u0026thinsp;0.000), 61.2%(P\u0026thinsp;=\u0026thinsp;0.000)respectively. Therefore, surgical treatment may not be limited to stage I L-LCNEC patients, but should be extended to resectable patients after adjuvant chemotherapy. Lobectomy or pneumonectomy could be conducted as soon as possible if the patient's physical condition allowed, because the cancer cells grow rapidly and patients may lose the chance of surgery within a few months.\u003c/p\u003e \u003cp\u003eL-LCNEC is aggressive with high potential to metastasize and is easy to recur after operation, so it is not enough to effectively treat the disease by surgery alone. L-LCNEC patients treated by surgery alone were rarely cured even in the early stage [\u003cspan citationid=\"CR26\" class=\"CitationRef\"\u003e26\u003c/span\u003e], which urges more scholars to consider chemotherapy or radiotherapy [\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e, \u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e, \u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e, \u003cspan citationid=\"CR28\" class=\"CitationRef\"\u003e28\u003c/span\u003e]. Two retrospective analysis showed that compared with the patients with surgery alone, platinum-based neoadjuvant chemotherapy or postoperative adjuvant chemotherapy could prolong the recurrence time of tumor and significantly benefit the long-term survival for the patients with early stage [\u003cspan citationid=\"CR29\" class=\"CitationRef\"\u003e29\u003c/span\u003e, \u003cspan citationid=\"CR30\" class=\"CitationRef\"\u003e30\u003c/span\u003e]. Chemotherapy regimens for small cell lung cancer/non-small cell lung cancer were used in L-LCNEC treatment, but most of the data were came from single center, small sample or retrospective studies, and the results were controversial [\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e, \u003cspan citationid=\"CR31\" class=\"CitationRef\"\u003e31\u003c/span\u003e, \u003cspan citationid=\"CR32\" class=\"CitationRef\"\u003e32\u003c/span\u003e]. For patients with advanced L-LCNEC, chemotherapy could significantly improve overall survival [\u003cspan additionalcitationids=\"CR34 CR35\" citationid=\"CR33\" class=\"CitationRef\"\u003e33\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e]. Our study also showed that chemotherapy may have a survival advantage. Since SEER database does not contain records of chemotherapy regimens, the topic which chemotherapy is better for L-LCNEC patients was not involved in our study.\u003c/p\u003e \u003cp\u003eBecause of the low incidence, there were a few literatures on radiotherapy for L-LCNEC. Mackley believed that if gross residual disease was present after surgery, adjuvant radiation should be recommended, adjuvant radiotherapy could be beneficial to local control and reduced the risk of local recurrence [\u003cspan citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e]. Rieber conclued that patients with incomplete resection showed a survival benefit from adjuvant radiotherapy [\u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e]. Our results also supported the prognostic benefits of radiotherapy.\u003c/p\u003e \u003cp\u003eThrough the establishment of nomogram, we could predict individualized prognosis according to their scores in order to select an appropriate treatment strategy for individuals.\u003c/p\u003e \u003cp\u003eThere were some limitations in our study: this was a retrospective study, our results are inevitable subject to selection bias. In addition, due to the limited clinical factors included in SEER database, this study did not analyze the possible factors related to the prognosis of the disease, such as smoking record, genes status, chemotherapy schemes, ect.. Therefore, it is necessary for a prospective evaluation for the nomogram in clinical application.\u003c/p\u003e "},{"header":"Conclusion","content":" \u003cp\u003eIn this study, our analysis indicated that age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy were independent prognostic factors for overall survival of L-LCNEC patients. And on this basis, we constructed a visual nomogram prognosis model, which had the potential to predict the 1-year and 3-year survival rate of L-LCNEC patients, and could be used as an assistant prediction tool in clinical practice.\u003c/p\u003e "},{"header":"Abbreviations","content":" \u003cdiv class=\"DefinitionList\"\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eL-LCNEC\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eLung large cell neuroendocrine carcinoma;\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eNETs\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eneuroendocrine tumors;\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eSEER\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eThe Surveillance, Epidemiology and End Results;\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eOS\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eOverall survival; AJCC:American Joint Committee on Cancer;\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eAUROC\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eArea under the receive operator characteristic curve\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003c/div\u003e "},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eAcknowledgments: \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWe would like to give special thanks to the efforts of the SEER tumor registry team.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors\u0026rsquo; contributions: \u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e(I) Conception and design: Dong Han, Qi Fu; (II) Data analysis and interpretation: All authors; (III) Manuscript writing: All authors; (IV) Final approval of manuscript: All authors.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe research for this manuscript was not financially supported and none of the authors had any relevant financial relationships.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAvailability of data and materials:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAll analyzed data are publicly available at the SEER website (\u003ca href=\"http://www.seer\"\u003ehttp://www.seer\u003c/a\u003e. cancer.gov), and should be requested under the approval of the SEER Program administration.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthics approval and consent to participate:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study used a general dataset from the Surveillance, Epidemiology, and End Results database built by a public health program, and therefore did not require institutional review board approval.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConsent for publication: \u003c/strong\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCompeting interests:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare that they have no competing interests.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthor details\u003c/strong\u003e\u003c/p\u003e\n\u003col\u003e\n\u003cli\u003eDepartment of Oncology \u0026amp; Hematology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China;\u003c/li\u003e\n\u003cli\u003eGraduate School, China Academy of Chinese Medical Sciences, Beijing, China\u003c/li\u003e\n\u003c/ol\u003e"},{"header":"References","content":"\u003cp class=\"EndNoteBibliography\"\u003e1. Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin 2015;65:87-108.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e2. Fasano M, Della Corte CM, Papaccio F, et al. Pulmonary Large-Cell Neuroendocrine Carcinoma: From Epidemiology to Therapy. J Thorac Oncol 2015;10:1133-41.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e3. Travis WD. Advances in neuroendocrine lung tumors. Ann Oncol 2010;21 Suppl 7:vii65-71.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e4. Gridelli C, Rossi A, Airoma G, et al. Treatment of pulmonary neuroendocrine tumours: state of the art and future developments. Cancer Treat Rev 2013;39:466-72.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e5. Battafarano RJ, Fernandez FG, Ritter J, et al. Large cell neuroendocrine carcinoma: an aggressive form of non-small cell lung cancer. J Thorac Cardiovasc Surg 2005;130:166-72.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e6. Sarkaria IS, Iyoda A, Roh MS, et al. Neoadjuvant and adjuvant chemotherapy in resected pulmonary large cell neuroendocrine carcinomas: a single institution experience. Ann Thorac Surg 2011;92:1180-6; discussion 6-7.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e7. Naidoo J, Santos-Zabala ML, Iyriboz T, et al. Large Cell Neuroendocrine Carcinoma of the Lung: Clinico-Pathologic Features, Treatment, and Outcomes. Clin Lung Cancer 2016;17:e121-e9.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e8. Filosso PL, Guerrera F, Evangelista A, et al. Adjuvant chemotherapy for large-cell neuroendocrine lung carcinoma: results from the European Society for Thoracic Surgeons Lung Neuroendocrine Tumours Retrospective Database. Eur J Cardiothorac Surg 2017;52:339-45.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e9. Karakiewicz PI, Briganti A, Chun FK, et al. Multi-institutional validation of a new renal cancer-specific survival nomogram. J Clin Oncol 2007;25:1316-22.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e10. Tang XR, Li YQ, Liang SB, et al. Development and validation of a gene expression-based signature to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma: a retrospective, multicentre, cohort study. Lancet Oncol 2018;19:382-93.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e11. Mariani L, Miceli R, Kattan MW, et al. Validation and adaptation of a nomogram for predicting the survival of patients with extremity soft tissue sarcoma using a three-grade system. Cancer 2005;103:402-8.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e12. Sternberg CN. Are nomograms better than currently available stage groupings for bladder cancer? J Clin Oncol 2006;24:3819-20.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e13. Wang L, Hricak H, Kattan MW, et al. Prediction of organ-confined prostate cancer: incremental value of MR imaging and MR spectroscopic imaging to staging nomograms. Radiology 2006;238:597-603.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e14. Sanchez de Cos Escuin J. Diagnosis and treatment of neuroendocrine lung tumors. Arch Bronconeumol 2014;50:392-6.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e15. Iyoda A, Hiroshima K, Moriya Y, et al. Postoperative recurrence and the role of adjuvant chemotherapy in patients with pulmonary large-cell neuroendocrine carcinoma. J Thorac Cardiovasc Surg 2009;138:446-53.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e16. Glisson BS, Moran CA. Large-cell neuroendocrine carcinoma: controversies in diagnosis and treatment. J Natl Compr Canc Netw 2011;9:1122-9.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e17. Varlotto JM, Medford-Davis LN, Recht A, et al. Should large cell neuroendocrine lung carcinoma be classified and treated as a small cell lung cancer or with other large cell carcinomas? J Thorac Oncol 2011;6:1050-8.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e18. Fournel L, Falcoz PE, Alifano M, et al. Surgical management of pulmonary large cell neuroendocrine carcinomas: a 10-year experience. Eur J Cardiothorac Surg 2013;43:111-4.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e19. Iyoda A, Jiang SX, Travis WD, et al. Clinicopathological features and the impact of the new TNM classification of malignant tumors in patients with pulmonary large cell neuroendocrine carcinoma. Mol Clin Oncol 2013;1:437-43.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e20. Filosso PL, Ruffini E, Di Gangi S, et al. Prognostic factors in neuroendocrine tumours of the lung: a single-centre experience. Eur J Cardiothorac Surg 2014;45:521-6; discussion 6.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e21. Sakurai H, Asamura H. Large-cell neuroendocrine carcinoma of the lung: surgical management. Thorac Surg Clin 2014;24:305-11.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e22. Eichhorn F, Dienemann H, Muley T, et al. Predictors of survival after operation among patients with large cell neuroendocrine carcinoma of the lung. Ann Thorac Surg 2015;99:983-9.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e23. Filosso PL, Rena O, Guerrera F, et al. Clinical management of atypical carcinoid and large-cell neuroendocrine carcinoma: a multicentre study on behalf of the European Association of Thoracic Surgeons (ESTS) Neuroendocrine Tumours of the Lung Working Groupdagger. Eur J Cardiothorac Surg 2015;48:55-64.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e24. Roesel C, Terjung S, Weinreich G, et al. A Single-Institution Analysis of the Surgical Management of Pulmonary Large Cell Neuroendocrine Carcinomas. Ann Thorac Surg 2016;101:1909-14.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e25. Mochizuki E, Matsuura S, Oishi K, et al. Surgical resection for clinical stage I high-grade neuroendocrine carcinoma of the lung. World J Surg Oncol 2018;16:33.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e26. Saji H, Tsuboi M, Matsubayashi J, et al. Clinical response of large cell neuroendocrine carcinoma of the lung to perioperative adjuvant chemotherapy. Anticancer Drugs 2010;21:89-93.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e27. Veronesi G, Morandi U, Alloisio M, et al. Large cell neuroendocrine carcinoma of the lung: a retrospective analysis of 144 surgical cases. Lung Cancer 2006;53:111-5.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e28. Kim KW, Kim HK, Kim J, et al. Outcomes of Curative-Intent Surgery and Adjuvant Treatment for Pulmonary Large Cell Neuroendocrine Carcinoma. World J Surg 2017;41:1820-7.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e29. Iyoda A, Hiroshima K, Toyozaki T, et al. Adjuvant chemotherapy for large cell carcinoma with neuroendocrine features. Cancer 2001;92:1108-12.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e30. Kujtan L, Muthukumar V, Kennedy KF, et al. The Role of Systemic Therapy in the Management of Stage I Large Cell Neuroendocrine Carcinoma of the Lung. J Thorac Oncol 2018;13:707-14.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e31. Sun JM, Ahn MJ, Ahn JS, et al. Chemotherapy for pulmonary large cell neuroendocrine carcinoma: similar to that for small cell lung cancer or non-small cell lung cancer? Lung Cancer 2012;77:365-70.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e32. Derks JL, van Suylen RJ, Thunnissen E, et al. Chemotherapy for pulmonary large cell neuroendocrine carcinomas: does the regimen matter? Eur Respir J 2017;49.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e33. Shimada Y, Niho S, Ishii G, et al. Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens. Lung Cancer 2012;75:368-73.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e34. Le Treut J, Sault MC, Lena H, et al. Multicentre phase II study of cisplatin-etoposide chemotherapy for advanced large-cell neuroendocrine lung carcinoma: the GFPC 0302 study. Ann Oncol 2013;24:1548-52.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e35. Niho S, Kenmotsu H, Sekine I, et al. Combination chemotherapy with irinotecan and cisplatin for large-cell neuroendocrine carcinoma of the lung: a multicenter phase II study. J Thorac Oncol 2013;8:980-4.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e36. Tokito T, Kenmotsu H, Watanabe R, et al. Comparison of chemotherapeutic efficacy between LCNEC diagnosed using large specimens and possible LCNEC diagnosed using small biopsy specimens. Int J Clin Oncol 2014;19:63-7.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e37. Mackley HB, Videtic GM. Primary carcinoid tumors of the lung: a role for radiotherapy. Oncology (Williston Park) 2006;20:1537-43; discussion 44-5, 49.\u003c/p\u003e\n\u003cp class=\"EndNoteBibliography\"\u003e38. Rieber J, Schmitt J, Warth A, et al. Outcome and prognostic factors of multimodal therapy for pulmonary large-cell neuroendocrine carcinomas. Eur J Med Res 2015;20:64.\u003c/p\u003e"},{"header":"Tables","content":"\u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 10px; font-family: Verdana, Geneva, sans-serif;\"\u003eTable 1 \u0026nbsp;Demographics and Clinical characteristics of patients\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 784px;border-collapse: collapse;border: none;\" width=\"100%\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eClinical parameters\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eNo. of\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003ePatients\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eNo. of\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003etraining cohort\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eNo. of\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003evalidation cohort\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eAge at diagnosis\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026lt;60\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e849（26.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e601（26.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e248（25.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e≥60\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2367（73.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1651（73.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e716（74.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cspan style=\"background-color: white;\"\u003eSex\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cspan style=\"color: red;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cspan style=\"color: red;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cspan style=\"color: red;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1725（53.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1198（53.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e527（54.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1491（46.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1054（46.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e437（45.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRace\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eWhite\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2702（84.0%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1897（84.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e805（83.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eBlack\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e378（11.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e262（11.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e116（12.0%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eOther\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e136（4.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e93（4.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e43（4.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMarital status at diagnosis\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; Married\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1722（53.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1178（52.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e544（56.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; Non-married\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1494（46.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1974（47.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e420（43.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cspan style=\"background-color: white;\"\u003eYear of diagnosis\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2004\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e174 \u0026nbsp;(5.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e126 \u0026nbsp;(5.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e48 \u0026nbsp;(5.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2005\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e183 \u0026nbsp;(5.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e119 \u0026nbsp;(5.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e64 \u0026nbsp;(6.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2006\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e228 \u0026nbsp;(7.1%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e164 \u0026nbsp;(7.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e64 \u0026nbsp;(6.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2007\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e242 \u0026nbsp;(7.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e169 \u0026nbsp;(7.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e73 \u0026nbsp;(7.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2008\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e235 \u0026nbsp;(7.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e162 \u0026nbsp;(7.2%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e73 \u0026nbsp;(7.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2009\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e278 \u0026nbsp;(8.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e196 \u0026nbsp;(8.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e82 \u0026nbsp;(8.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2010\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e294 \u0026nbsp;(9.1%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e194 \u0026nbsp;(8.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e100 (10.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2011\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e274 \u0026nbsp;(8.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e202 \u0026nbsp;(9.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e72 \u0026nbsp;(7.5%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2012\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e319 \u0026nbsp;(9.9%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e232 \u0026nbsp;(10.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e87 \u0026nbsp;(9.0%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2013\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e347 \u0026nbsp;(10.8%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e244 \u0026nbsp;(10.8%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e103 (10.7%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2014\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e332 \u0026nbsp;(10.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e234 \u0026nbsp;(10.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e98 \u0026nbsp;(10.2%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2015\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e310 \u0026nbsp;(9.6%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e210 \u0026nbsp;(9.3%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e100 (10.4%)\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003ePrimary tumor Site\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMain bronchus\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e117（3.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e83（3.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e34（3.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eUpper lobe\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1762（54.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1209（53.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e553（57.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMiddle lobe\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e143（4.4）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e106（4.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e37（3.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLower lobe\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e773（24.0）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e567（25.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e206（21.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eOverlapping lesion\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e37（1.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e27（1.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e10（1.0%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eNOS\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e384（11.9%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e260（11.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e124（12.9%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eGrade\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eWell differentiated\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e14（0.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e8（0.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e6（0.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 9pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eModerately differentiated\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e49（1.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e35（1.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e14（4.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003ePoorly differentiated\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1166（36.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e825（36.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e341（35.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eUndifferentiated;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e386（12.0%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e270（12.0%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e116（12.0%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eUnknown\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1601（49.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1114（49.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e487（50.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTNM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eI\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e903（28.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e641（28.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e262（27.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eII\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e205（6.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e145（6.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e69（6.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eIII\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e690（21.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e483（21.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e207（21.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eIV\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1418（44.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e983（43.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e435（45.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eSurgical\u0026nbsp;therapy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; No\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1931（60.0%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1345（59.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e586（60.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; Local tumor destruction\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e4（0.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2（0.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2（0.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 9pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLess than one lobe resection\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e325（10.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e235（10.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e90（9.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLobectomy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e851（26.5%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e595（25.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e256（26.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003ePneumonectomy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e105（3.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e75（3.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e30（3.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRadiotherapy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eNo\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1924（59.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1332（59.1%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e592（61.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eYes\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1292（40.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e920（40.9%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e372（38.6\u0026amp;）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eChemotherapy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border: none;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eNo\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1453（45.2%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border: none;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1022（45.4%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border: none;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e431（44.7%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 248.59375px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"34.02061855670103%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eYes\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1763（54.8%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 157.640625px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"21.649484536082475%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1230（54.6%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 162.65625px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"22.68041237113402%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e533（55.3%）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cstrong\u003e\n \u003cbr\u003e\n \u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\n \u003cbr\u003e\n \u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cstrong\u003eTable2 \u0026nbsp; Univariable analysis and Multivariable analysis of Training Cohort\u003c/strong\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellpadding=\"0\" cellspacing=\"0\" style=\"width: 784px;border-collapse: collapse;border: none;\" width=\"100%\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 180.5px;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"25.252525252525253%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eParameters\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.28125px;border-style: solid none none;border-top-width: 1pt;border-top-color: windowtext;padding: 0in 5.4pt;\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eUnivariable analysis\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.125px;border-style: solid none none;border-top-width: 1pt;border-top-color: windowtext;padding: 0in 5.4pt;\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMultivariable analysis\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 73.5px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"12.5%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eHR\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"22.22222222222222%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e95%CI\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"15.277777777777779%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cem\u003eP\u003c/em\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"12.5%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eHR\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"25%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e95%CI\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"12.5%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cem\u003eP\u003c/em\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 268.375px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"35.714285714285715%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cspan style=\"background-color: white;\"\u003eAge at diagnosis\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.3265306122449%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.224489795918368%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.183673469387756%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.367346938775512%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.183673469387756%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.252525252525253%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026lt;60\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.28125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e≥60\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.359\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.216-1.519\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 31.5pt 0.0001pt 0in;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.407\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.253-1.579\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eSex\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.252525252525253%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.28125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.850\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.773-0.936\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.001\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 31.5pt 0.0001pt 0in;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.773\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.699-0.855\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRace\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.252525252525253%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eBlack\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.28125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eWhite\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 31.5pt 0.0001pt 0in;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.030\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.887-1.196\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.698\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.953\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.817-1.112\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.539\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eOther\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 31.5pt 0.0001pt 0in;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.068\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.843-1.353\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.586\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.991\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.779-1.260\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.939\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMarital status at diagnosis\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; Married\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; Non-married\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.064\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.967-1.171\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.201\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.080\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.975-1.196\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.141\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.252525252525253%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u003cspan style=\"background-color: white;\"\u003eYear of diagnosis\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.28125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 280.125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"37.37373737373738%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2004\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2005\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.204\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.919-1.577\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.179\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.179\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.896-1.550\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.240\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2006\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.093\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.850-1.405\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.488\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.099\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.851-1.417\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.470\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2007\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.193\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.928-1.533\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.169\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.956\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.740-1.234\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.729\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2008\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.073\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.830-1.387\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.591\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.968\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2009\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.154\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.903-1.477\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.253\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.068\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.831-1.374\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.606\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2010\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.063\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.828-1.365\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.633\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.968\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.750-1.244\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.801\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2011\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.285\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.003-1.645\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.047\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.179\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 9pt 0.0001pt 0in;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.917-1.516\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.200\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2012\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.351\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.061-1.720\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.015\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.088\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.851-1.392\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.500\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, 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10px;\"\u003e0.937-1.533\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.149\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.073\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2014\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.429\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.109-1.840\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.006\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.113\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.860-1.441\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.415\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2015\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.317\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.959-1.810\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.089\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.159\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.839-1.599\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.371\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003ePrimary tumor Site\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMain bronchus\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eUpper lobe\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.450\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.355-0.572\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.722\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.567-0.919\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.008\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan 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180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLower lobe\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.448\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n 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16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.746\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.579-0.960\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, 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style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eWell differentiated\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 9pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eModerately differentiated\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.757\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.285-2.007\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.575\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.933\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.349-2.495\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.890\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003ePoorly differentiated\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.986\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.409-2.379\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.975\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.127\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.464-2.736\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.792\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eUndifferentiated;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.125\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.463-2.734\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.749\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.279\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.523-3.128\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.590\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eUnknown\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.592\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.661-3.834\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.300\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.093\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.450-2.651\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.844\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTNM\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n 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width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eII\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.568\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.248-1.971\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n 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style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2.090-2.808\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" 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10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e4.021\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e3.329-4.856\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eSurgical\u0026nbsp;therapy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; No\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp; Local tumor destruction\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.501\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.070-3.559\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.489\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.706\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.099-5.051\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.729\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 9pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLess than one lobe resection\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.361\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.305-0.427\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.529\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.431-0.651\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLobectomy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.247\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.217-0.281\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.387\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.322-0.465\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003ePneumonectomy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.309\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.229-0.470\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.388\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.281-0.536\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRadiotherapy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: DengXian;line-height: 16pt;text-align: left;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;line-height: 16pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eNo\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.00（Ref）\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: right;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;text-indent: 10.5pt;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eYes\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.413\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1.283-1.557\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.833\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 122.8125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"18.556701030927837%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.749-0.928\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.001\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 180.5px;border: none;padding: 0in 5.4pt;\" width=\"25.77319587628866%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eChemotherapy\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 108.53125px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"16.49484536082474%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 69.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"11.34020618556701%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 73.5px;border: none;padding: 0in 5.4pt;vertical-align: top;\" valign=\"top\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: 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10px;\"\u003e0.500-0.624\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55.0625px;border-style: none none solid;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;height: 13.95pt;\" width=\"9.278350515463918%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e0.000\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style=\"margin: 0in 0in 0.0001pt;text-align: justify;font-size:14px;font-family: DengXian;\"\u003e\u003cspan style=\"font-size: 10px; font-family: Verdana, Geneva, sans-serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Lung large cell neuroendocrine carcinoma (L-LCNEC), nomogram, Overall survival, SEER","lastPublishedDoi":"10.21203/rs.3.rs-16158/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-16158/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eBackground Lung large cell neuroendocrine carcinoma (L-LCNEC) has a poor prognosis with lower survival rate than other NSCLC patients. The estimation of an individual survival rate is puzzling. The main purpose of this study was to establish a more accurate model to predict the prognosis of L-LCNEC.\u003c/p\u003e\u003cp\u003eMethods Patients aged 18 years or older with L-LCNEC were identified from the Surveillance, Epidemiology and End Results (SEER) database from 2004 to 2015. Cox regression analysis was used to identify factors associated with survival time. The results were used to construct a nomogram to predict 1-year, and 3-year survival probability in L-LCNEC patients. Overall survival (OS) were compared between low risk group and high risk group by the Kaplan–Meier analysis.\u003c/p\u003e\u003cp\u003eResults A total of 3216 patients were included in the study. We randomly divided all included patients into 7:3 training and validating groups. In multivariable analysis of training cohort, age at diagnosis, sex, stage of tumor, surgical treatment, radiotherapy and chemotherapy were independent prognostic factors for OS. All these factors were incorporated to construct a nomogram, which was tested in the validating cohort.\u003c/p\u003e\u003cp\u003eConclusions we constructed a visual nomogram prognosis model, which had the potential to predict the 1-year and 3-year survival rate of L-LCNEC patients, and could be used as an assistant prediction tool in clinical practice.\u003c/p\u003e","manuscriptTitle":"Construction of a nomogram to predict overall survival for patients with lung large cell neuroendocrine carcinoma: analysis of the SEER database","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2020-03-05 22:03:40","doi":"10.21203/rs.3.rs-16158/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"f4830fe0-36b5-484a-aa75-34bcc08b606d","owner":[],"postedDate":"March 5th, 2020","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":66787,"name":"Oncology"},{"id":66788,"name":"Cancer Biology"}],"tags":[],"updatedAt":"2021-02-19T12:10:50+00:00","versionOfRecord":[],"versionCreatedAt":"2020-03-05 22:03:40","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-16158","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-16158","identity":"rs-16158","version":["v1"]},"buildId":"WvIrzKhiLBfengagbw6Ux","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}