Comparison of Visual Performance between Monofocal and Rotationally Asymmetric Refractive Intraocular Lenses

Masaki Miyoshi, Hirotaka Tanabe, Tomohiro Shojo, Tomofusa Yamauchi, Kosuke Takase, Hitoshi Tabuchi
2024 · doi:10.21203/rs.3.rs-2338587/v2
preprint OA: closed CC-BY-4.0
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Abstract

Abstract Objective or Purpose We compared the visual performance of a monofocal intraocular lens (IOL) (ZCB00) and a rotationally asymmetric refractive IOL with +1.5 diopters near addition (Lentis Comfort LS-313 MF15). Design Retrospective Comparative Case Series. Subjects, Participants, and/or Controls A total of 1352 eyes of 676 patients were enrolled; the ZCB00 group comprised 904 eyes of 452 patients (72.3 ± 6.8 years; females/males, 268/184), and the LS-313 MF15 group included 448 eyes of 224 patients (73.6 ± 7.0 years; females/males, 125/99). Methods, Intervention, or Testing We investigated postoperative parameters ten weeks after surgery from both eyes of cataract patients who underwent bilateral implantation with one of the two IOLs within three months between 2011 and 2019. A linear mixed-effects model was used for both eyes, strictly adjusting for sex, age, subjective refraction spherical equivalent, subjective refraction cylinder, corneal astigmatism, axial length, corneal higher-order aberrations, and pupil diameter to ensure statistical validity. Main Outcome Measures Visual acuity at different distances, contrast sensitivity with and without glare, the quality of vision assessed by the Japanese version of the NEI VFQ-25, and the use of spectacles after surgery. Results The corrected distance visual acuity was significantly better,and the higher-order aberrations (ocular/internal, scaled to a 4/6-mm pupil; WF_4_post_O_TotalHOA, _Third, _Fourth, _Trefoil, _Coma, _Tetrafoil, _Spherical; WF_4_post_I_TotalHOA, _Third, _Fourth, _Trefoil, _Coma, _Tetrafoil, _Spherical, WF_6_post_O_Spherical, and WF_6_post_I_Spherical) were significantly smaller in the ZCB00 group (p<0.00068, Wald test). Contrast sensitivity with glare (6.3 degrees) and spectacle independence (near) were significantly better in the LS-313 MF15 group (p<0.00068, Wald test). Conclusions In terms of visual parameters, each IOL group displayed different characteristics at a high level of performance.

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License: CC-BY-4.0