1-ARYLSULPHONYL, ARYL(THIO)CARBONYL PYRIDAZINO DERIVATIVES AND METHODS OF PREPARATION
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Novel non-steroidal heterocyclic pyridazino derivatives with high affinity for progestin receptors were developed and shown to be useful in treating endometriosis, contraception, menopause, and osteoporosis.
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Abstract
1-Arylsulphonyl, arylcarbonyl and aryl(thio)carbonyl pyridazino derivatives and processes for making said derivatives are described. The novel derivatives are non-steroidal heterocyclic compounds which act as selective progestins and/or antiprogestins having a high in vitro affinity for either the uterine, breast or bone progestin receptor. As such, the non-steroidal heterocyclic derivatives are useful in contraception, menopause, osteoporosis or endometriosis.
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- europepmc
- last seen: 2026-08-01T06:07:04.264727+00:00