Precise Estimation of In Vivo Protein Turnover Rates

Jonathon J. O’Brien, Vikram Narayan, Yao Wong, Phillip Seitzer, Celeste M. Sandoval, Nicole Haste, Megan Smith, Ramin Rad, Aleksandr Gaun, Adam Baker, Matthew Kukurugya, Baby Martin-McNulty, Chunlian Zhang, Ganesh Kolumam, Carmela Sidrauski, Vladimir Jojic, Fiona McAllister, Bryson Bennett, Rochelle Buffenstein
2020 · doi:10.1101/2020.11.10.377440
preprint OA: closed CC-BY-4.0
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

This paper developed a novel method for precisely estimating protein turnover rates in living organisms using stable isotope labeling and mass spectrometry.

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License: CC-BY-4.0