Pakistan journal of medical sciences

OBJECTIVE: To evaluate the therapeutic efficacy of bladder hydrodistension combined with oral mirabegron and intravesical instillation in patients with interstitial cystitis(IC). METHODOLOGY: This was a retrospective study. Ninety patients…

OBJECTIVE: The objective of the current study was to determine the efficacy of Cognitive Behavior Therapy (CBT-cp), Pelvic Floor Therapy (PFT), Integrated Therapy (Combination of CBT-cp and PFT), and Pharmacotherapy in the Treatment of Chro…

OBJECTIVE: Infertility a global health issue linked with untoward psychological and social impacts is due to a number of contributing factors; one of which is oxidative stress. This study aimed to determine the potential association of oxid…

OBJECTIVE: To determine the frequency and clinicopathological features of incidental premalignant and malignant gynecological lesions detected after hysterectomies performed for benign indications, and to identify associated risk factors. …

OBJECTIVE: To investigate the association between delivery/abortion methods, allergy history, and endometriosis (EM) risk. METHODOLOGY: This prospective case-control study was conducted at the First Affiliated Hospital of Naval Medical Uni…

OBJECTIVE: Bromocriptine has emerged as a potential treatment for adenomyosis. This study aimed to identify genes associated with Bromocriptine sensitivity and explore the biological processes and cell-type-specific expression patterns invo…

BACKGROUND & OBJECTIVE: Surgical site infections (SSIs) are a common complication following hysterectomy that is associated with higher morbidity, prolonged hospitalization, and a healthcare burden. Identifying key risk factors for SSIs wil…

OBJECTIVE: To explore the impact of a symptomics-based transitional care program on mental health and quality of life in perimenopausal women after total hysterectomy. METHODOLOGY: This retrospective study was conducted using medical recor…

OBJECTIVE: To explore factors influencing high-quality embryo rate in long protocols for controlled ovarian hyperstimulation (COH) during in vitro fertilization (IVF). METHODS: It was a retrospective case-control study including patients r…

OBJECTIVE: To examine if endometriosis affected outcomes of ovarian clear cell carcinoma (OCCC). METHODOLOGY: We searched for all study types on the databases of EMBASE, PubMed, Web of Science and Scopus. The search limits were 1st January…

BACKGROUND & OBJECTIVE: To assess the association of assisted reproductive technologies (ART) conception with postpartum hemorrhage (PPH) during the peripartum and postpartum periods. METHODS: Clinical records of 11,497 patients enrolled i…

OBJECTIVE: To explore the clinical efficacy of transumbilical laparoendoscopic single-site extracorporeal surgery (TU-LESS-E) in the treatment of giant ovarian cysts and huge cystic pelvic masses. METHODOLOGY: This was a retrospective stud…

OBJECTIVE: To compare the diagnostic performance of an exosomal ovarian cancer assay (chemiluminescence) with serum CA125 for epithelial ovarian cancer (EOC), focusing on sensitivity, specificity, positive predictive value (PPV), and negati…

OBJECTIVE: To investigate the correlation between endometriosis (EMs) severity and placenta accreta spectrum (PAS) risk in the subsequent pregnancy. METHOD: Clinical records of 2,142 patients who underwent laparoscopic surgery for EMs at F…

BACKGROUND & OBJECTIVE: The added value of lymphadenectomy is a widely debated topic, especially in cases of early-stage epithelial ovarian cancer (EOC). We present robust evidence through an updated systematic review and meta-analysis rega…

OBJECTIVE: To compare the clinical outcome of freeze-thawed embryo transfer at different embryonic development days in whole embryo freezing patients of different ages. METHODS: This was a retrospective study. Collected clinical data of 55…

OBJECTIVE: To explore the micro blood flow characteristics of normal singleton pregnancy placenta in middle and late pregnancy based on microvascular flow (MV-Flow) imaging. METHODS: We conducted a retrospective cohort study. Clinical reco…

OBJECTIVE: The aim of this study was to evaluate the impact of assisted reproductive technology (ART) on the risk of cerebral palsy (CP) in offspring. METHODS: We searched PubMed, Embase, Web of Science and Scopus databases for observation…

OBJECTIVE: To explore the influencing factors of polyspermy in long-term fertilization during in vitro fertilization (IVF) with antagonist protocol. METHODS: This was a retrospective case-control study. Patients with secondary infertility …

OBJECTIVE: To evaluate the efficacy of Fire Dragon Cupping (FDC) combined with Shaofu Zhuyu Decoction (SFZYD) in the treatment of primary dysmenorrhea (PD) with cold coagulation and blood stasis (CCBS). METHODOLOGY: A retrospective case-co…

OBJECTIVE: Sequential therapy in traditional Chinese medicine (TCM) refers to a combination of internal and external treatment methods in a certain order based on syndrome differentiation and therapy. The aim of this study was to evaluate t…

Injuries to the urinary tract are regrettable consequences of pelvic surgery. These often pertain to the bladder. The prevalence of iatrogenic ureteral injuries varies between 0.05% and 30%. Although certain lesions are identified intraoper…

OBJECTIVE: To analyze the value of serum human chorionic gonadotropin (β-HCG), anti-Mullerian hormone (AMH), progesterone (P)/ estradiol (E2) in predicting the pregnancy outcome of frozen-thawed embryo transfer (FET) cycle in patients with …

OBJECTIVE: To compare the pregnancy outcome of the fresh cycle or freeze-thaw cycle embryo transfer of patients treated with a long follicular phase regimen and antagonist regimen, and explore the clinical therapeutic effect of the two regi…

OBJECTIVE: To explore the choice of embryo transfer schemes for patients with low oocyte retrieval (≤ 3 oocytes). METHODS: A retrospective analysis was conducted on patients with oocyte yields ≤ 3 undergoing in vitro fertilization and embr…