Pakistan journal of medical sciences

OBJECTIVE: Infertility a global health issue linked with untoward psychological and social impacts is due to a number of contributing factors; one of which is oxidative stress. This study aimed to determine the potential association of oxid…

ObjectiveTo determine the frequency and clinicopathological features of incidental premalignant and malignant gynecological lesions detected after hysterectomies performed for benign indications, and to identify associated risk factors.Meth…

OBJECTIVE: To investigate the association between delivery/abortion methods, allergy history, and endometriosis (EM) risk. METHODOLOGY: This prospective case-control study was conducted at the First Affiliated Hospital of Naval Medical Uni…

OBJECTIVE: Bromocriptine has emerged as a potential treatment for adenomyosis. This study aimed to identify genes associated with Bromocriptine sensitivity and explore the biological processes and cell-type-specific expression patterns invo…

Background & objectiveSurgical site infections (SSIs) are a common complication following hysterectomy that is associated with higher morbidity, prolonged hospitalization, and a healthcare burden. Identifying key risk factors for SSIs will …

ObjectiveTo explore factors influencing high-quality embryo rate in long protocols for controlled ovarian hyperstimulation (COH) during in vitro fertilization (IVF).MethodsIt was a retrospective case-control study including patients receivi…

OBJECTIVE: To examine if endometriosis affected outcomes of ovarian clear cell carcinoma (OCCC). METHODOLOGY: We searched for all study types on the databases of EMBASE, PubMed, Web of Science and Scopus. The search limits were 1st January…

Background & objectiveTo assess the association of assisted reproductive technologies (ART) conception with postpartum hemorrhage (PPH) during the peripartum and postpartum periods.MethodsClinical records of 11,497 patients enrolled in Fuji…

ObjectiveTo explore the clinical efficacy of transumbilical laparoendoscopic single-site extracorporeal surgery (TU-LESS-E) in the treatment of giant ovarian cysts and huge cystic pelvic masses.MethodologyThis was a retrospective study. Six…

ObjectiveTo compare the diagnostic performance of an exosomal ovarian cancer assay (chemiluminescence) with serum CA125 for epithelial ovarian cancer (EOC), focusing on sensitivity, specificity, positive predictive value (PPV), and negative…

OBJECTIVE: To investigate the correlation between endometriosis (EMs) severity and placenta accreta spectrum (PAS) risk in the subsequent pregnancy. METHOD: Clinical records of 2,142 patients who underwent laparoscopic surgery for EMs at F…

Background & objectiveThe added value of lymphadenectomy is a widely debated topic, especially in cases of early-stage epithelial ovarian cancer (EOC). We present robust evidence through an updated systematic review and meta-analysis regard…

ObjectiveTo compare the clinical outcome of freeze-thawed embryo transfer at different embryonic development days in whole embryo freezing patients of different ages.MethodsThis was a retrospective study. Collected clinical data of 558 pati…

ObjectiveTo explore the micro blood flow characteristics of normal singleton pregnancy placenta in middle and late pregnancy based on microvascular flow (MV-Flow) imaging.MethodsWe conducted a retrospective cohort study. Clinical records an…

ObjectiveThe aim of this study was to evaluate the impact of assisted reproductive technology (ART) on the risk of cerebral palsy (CP) in offspring.MethodsWe searched PubMed, Embase, Web of Science and Scopus databases for observational stu…

ObjectiveTo explore the influencing factors of polyspermy in long-term fertilization during in vitro fertilization (IVF) with antagonist protocol.MethodsThis was a retrospective case-control study. Patients with secondary infertility underg…

ObjectiveTo evaluate the efficacy of Fire Dragon Cupping (FDC) combined with Shaofu Zhuyu Decoction (SFZYD) in the treatment of primary dysmenorrhea (PD) with cold coagulation and blood stasis (CCBS).MethodologyA retrospective case-control …

ObjectiveSequential therapy in traditional Chinese medicine (TCM) refers to a combination of internal and external treatment methods in a certain order based on syndrome differentiation and therapy. The aim of this study was to evaluate the…

Injuries to the urinary tract are regrettable consequences of pelvic surgery. These often pertain to the bladder. The prevalence of iatrogenic ureteral injuries varies between 0.05% and 30%. Although certain lesions are identified intraoper…

ObjectiveTo analyze the value of serum human chorionic gonadotropin (β-HCG), anti-Mullerian hormone (AMH), progesterone (P)/ estradiol (E2) in predicting the pregnancy outcome of frozen-thawed embryo transfer (FET) cycle in patients with lo…

ObjectiveTo compare the pregnancy outcome of the fresh cycle or freeze-thaw cycle embryo transfer of patients treated with a long follicular phase regimen and antagonist regimen, and explore the clinical therapeutic effect of the two regime…

ObjectiveTo explore the choice of embryo transfer schemes for patients with low oocyte retrieval (≤ 3 oocytes).MethodsA retrospective analysis was conducted on patients with oocyte yields ≤ 3 undergoing in vitro fertilization and embryo tra…

ObjectiveTo compare the efficacy of letrozole vs Clomiphene citrate for ovulation induction in PCOS women.MethodsThis double blind randomized controlled trial was conducted at Services Hospital, Lahore, from January 2016 to December 2020. T…

Background & objectivesThe relationship of Vitamin-D (VD) with Luteinizing Hormone (LH), Follicle stimulating Hormone (FSH) and Anti Mullerian Hormone (AMH) is recognized. This study was conducted to determine whether VD is a predictor of f…

ObjectiveThe study aimed to demonstrate the efficacy and safety of an innovative hemostatic technique in managing Placenta Previa and Accreta Spectrum by S. Rao Spiral Suturing (SRSS) of a lower uterine segment.MethodIn this retrospective s…