European journal of drug metabolism and pharmacokinetics
Eur J Drug Metab Pharmacokinet
· ISSN (e) 2107-0180
· 2 papers in corpus
other
BACKGROUND: Overactive adenosine triphosphate signaling via P2X3 homotrimeric receptors is implicated in multiple conditions. To fully understand the metabolism and elimination pathways of eliapixant, a study was conducted to assess the pha…
2018
Background and objectivesPrevious studies have demonstrated the metabolism of tibolone through sulfation, with the cytosolic sulfotransferase (SULT) SULT2A1 as the major responsible enzyme. The current study aimed to investigate how SULT2A1…