Current pharmaceutical biotechnology

Curr Pharm Biotechnol · ISSN (e) 1873-4316 · 6 papers in corpus
lab-animal 2025
doi:10.2174/0113892010331129250216041033 ·PMID:39980288

AIMS: The present study aimed to examine the roles of circRNA-circSMAD2 and its regulatory mechanisms in endometriosis (EMs). BACKGROUND: Evidence has confirmed that circRNAs play multiple roles in regulating the occurrence and development…

other 2020
doi:10.2174/1389201021666191227121627 ·PMID:31880256

BACKGROUND: Endometrial cancer is one of the most common gynecological cancer in the developed countries and occurs mainly in postmenopausal women. Angiogenesis is important for cancer formation as it provides nutrients for growing tumor ma…

other 2019
doi:10.2174/1389201020666190619145655 ·PMID:31215376

BACKGROUND: In the course of neoplastic diseases, a reduction in SEMA3F expression is observed, which translates into an increase in the proliferative and proangiogenic potential of cells forming the tumor and the surrounding microenvironme…

observational 2019
doi:10.2174/1389201020666190717092448 ·PMID:31322068

BACKGROUND: VEGF-A, VEGF-B, VEGFR-1 and VEGFR-2 are important proteins involved in the induction and development of a new blood vessel network through which the tumor is properly nourished and oxygenated. OBJECTIVES: The aim of the study w…

observational 2019
doi:10.2174/1389201020666190408112822 ·PMID:30961491

BACKGROUND: EDIL3 is an extracellular matrix protein that plays a key role in angiogenesis. Changes in the pattern of its expression also affect cellular processes and the tumor microenvironment. Elevated level of EDIL3 is considered an unf…

other 2019
doi:10.2174/1389201020666190219121602 ·PMID:30806307

BACKGROUND: Neuropilins (NRPs) participate in many processes related to cancer development such as angiogenesis, lymphangiogenesis and metastasis. Although endometrial cancer is one of the most common gynecological cancers, it has not been …