Immunology and cell biology

Clodronate-loaded liposomes (CL liposomes) have been widely employed to deplete different macrophage subpopulations to assess their role in homeostatic, repair, regulatory, defense, autoimmune and inflammatory processes. Administration of C…

Tumor-associated macrophages (TAMs) exert tumor-promoting effects. There have been reports that estrogen receptors (ERs) are expressed on the infiltrating macrophages of endometriosis, ovarian cancer and lung cancer. However, the role of ER…

Since its discovery, diverse functions have been attributed to the G0/G1 switch gene 2 (G0S2), from lipid metabolism to control of cell proliferation. Our group showed for the first time that G0S2 promotes quiescence in hematopoietic stem c…