Contemporary clinical trials communications

article 2023

A supportive text message intervention for individuals living with endometriosis (EndoSMS): Randomized controlled pilot and feasibility trial

doi:10.1016/j.conctc.2023.101093 ·PMID:36895681

INTRODUCTION: As a high symptom burden chronic condition, endometriosis is associated with diminished quality of life (QoL) and psychological distress. The EndoSMS text message intervention was developed to inform and support individuals li…

article 2023

The efficacy of GnRH-a followed by SanJieZhenTong capsules in long-term management of endometriosis: Study protocol for a multicenter, double-blinded, double-dummy randomized clinical trial

doi:10.1016/j.conctc.2023.101179 ·PMID:37409188

BACKGROUND: Endometriosis is a common benign gynecological disorder with high risk of recurrence and adverse impact on fertility-sparing. This study aims to evaluate the effectiveness and safety of SanJieZhenTong Capsules, a traditional Chi…

2022

Protocol for double-blind RCT of acupuncture for vulvodynia.

doi:10.1016/j.conctc.2022.101029 ·PMID:36387991

BackgroundVulvodynia, vulvar pain of unknown origin lasting at least 3 months, affects 7% of American women. Dyspareunia, its frequent companion, renders sexual intercourse virtually impossible. Although few therapies are efficacious and ra…

2021

Influence of the natural hormonal milieu on brain and behavior in women who smoke cigarettes: Rationale and methodology.

doi:10.1016/j.conctc.2021.100738 ·PMID:33718654

Women experience more severe health consequences from smoking, have greater difficulty quitting, and respond less favorably to nicotine replacement therapy than men. The influence of fluctuating ovarian hormones, specifically estradiol (E) …

2020

Feasibility and acceptability of testing a menstrual-cycle timed smoking cessation intervention for women of reproductive age (Project Phase): Protocol of a pilot randomized controlled trial.

doi:10.1016/j.conctc.2020.100569 ·PMID:32435718

BackgroundCompared to men, women have unique barriers to smoking cessation and are less likely to utilize quitline services. While current clinical recommendations have called for sex/gender-specific smoking cessation protocols, quitlines h…