Journal of enzyme inhibition and medicinal chemistry
J Enzyme Inhib Med Chem
· ISSN (e) 1475-6374
· 1 paper in corpus
A comprehensive set of 3-phenylcoumarin analogues with polar substituents was synthesised for blocking oestradiol synthesis by 17-β-hydroxysteroid dehydrogenase 1 (HSD1) in the latter part of the sulphatase pathway. Five analogues produced …