Journal of enzyme inhibition and medicinal chemistry

J Enzyme Inhib Med Chem · ISSN (e) 1475-6374 · 1 paper in corpus
other 2018
doi:10.1080/14756366.2018.1452919 ·PMID:29620427

A comprehensive set of 3-phenylcoumarin analogues with polar substituents was synthesised for blocking oestradiol synthesis by 17-β-hydroxysteroid dehydrogenase 1 (HSD1) in the latter part of the sulphatase pathway. Five analogues produced …