Seminars in diagnostic pathology

Clinical application of exogenous hormone as a method of contraception and/or treatment of various gynecologic disorders is exceedingly common. Unfortunately, the concurrent use of these agents also complicates the interpretation of patholo…

Mutations and other molecular events involving subunits of the SWI/SNF chromatin remodelling complex are common in a wide variety of malignancies, including those arising at various sites in the female genital tract. Endometrioid and clear …

The widespread use of abdominal ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) has resulted in an increased identification of asymptomatic pancreatic lesions. Preoperative diagnoses of pancreatic lesions can…

A variety of miscellaneous conditions affect the appendix, both as incidental findings and as causes of clinical signs and symptoms that often mimic appendicitis. Congenital abnormalities of the appendix are rare; the two most commonly repo…

Selected tumor-like lesions of the urinary bladder and urethra, particularly those that have been the subject of recent attention in the literature, are reviewed. Within the category of epithelial abnormalities, it has recently been appreci…

Ectopic tissues rarely occur in the lung. They include endometriosis, neurological tissue, thyroid, pancreas, and adrenal. Choristomas are very rare developmental anomalies derived from these ectopic tissues. They develop as a mass composed…

Diverse nonneoplastic glandular lesions of the uterine cervix may occasionally be misinterpreted as premalignant or malignant. These processes include papillary endocervicitis, tunnel clusters, deep glands and deep nabothian cysts, microgla…

Despite earlier arguments that the so-called "endometrioid carcinoma" is of Müllerian remnant origin, our clinicopathologic study of 35 cases indicated that it is actually an adenocarcinoma of prostatic duct origin. With respect to histolog…

The clinical and pathologic features and the differential diagnosis of uterine tumors containing mixed epithelial and mesenchymal elements are reviewed. The malignant mullerian mixed tumor (MMMT) is the most common neoplasm in this group, w…