Zhonghua fu chan ke za zhi

OBJECTIVE: To investigate the relationship between the distribution of nerve fibers in multiple endometriosis lesions and pelvic pain. METHODS: From Sept. 2007 to Sept. 2008, 120 endometriosis patients treated in Peking Union Hospital were…

OBJECTIVE: to investigate the relationship between the ultrastructural features combined with the expression of connexin (Cx43) protein in uterine junction zone and pathogenesis of adenomyosis. METHODS: from Nov. 2008 to Nov. 2009, 30 pati…

OBJECTIVE: To evaluate long term effect and related factors in patients with menorrhagia treated by microwave endometrial ablation (MEA). METHODS: Total of 334 women with menorrhagia were treated by MEA, the range of age was from 29 to 59 …

OBJECTIVE: To investigate clinicopathological features of endometriosis-associated epithelial ovarian carcinoma. METHODS: Retrospective follow-up study, clinicopathological data from patients with ovarian epithelial carcinoma were retrieve…

OBJECTIVE: To study the incidence of pelvic adhesions in endometriosis (EM) and the relationship between pelvic adhesions and pain symptoms. METHODS: The incidence of pelvic adhesions, dysmenorrhea, chronic pelvic pain, dyspareunia, dyschi…

OBJECTIVE: To investigate nerve fibers distribution in endometrium of adenomyosis and their relationship with dysmenorrhea. METHODS: Endometrial tissue was sampled from 74 hysterectomy specimens including 32 cases with adenomyosis and 42 c…

OBJECTIVE: To evaluate effects and safety of gonadotrophin-releasing hormone agonist (GnRH-a) combined with transdermal estradiol and medroxyprogesterone acetate in the treatment of endometriosis. METHODS: From January 1st, 2007 to July 31…

OBJECTIVE: To establish the diagnostic model for endometriosis by screening the plasma biomarkers of endometriosis using surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS)coupled with bioinformatics…

OBJECTIVE: To investigate the expression of integrin beta3 and osteopontin (OPN) in eutopic and ectopic endometrium of adenomyosis. METHODS: From January 2007 to July 2008, the endometrium specimens were collected from 43 patients with ade…

OBJECTIVE: To investigate the influence on ovarian reserve function in treatment of ovarian endometriotic cyst by laparoscopic cystectomy with various hemostasis management. METHODS: From September 2007 to August 2008, 61 patients with bil…

OBJECTIVE: To investigate the relationship between degree of endometrioma adhesions and clinical feature, surgical treatment and postoperative recurrence. METHODS: From Jan 2003 to Mar 2008, 662 patients with endometrioma undergoing laparo…

OBJECTIVE: To investigate the safety and efficacy of transvaginal hydrolaparoscopic pelvic adhesiolysis (THLPA) treatment in the infertile women. METHODS: From May 2007 to Sep. 2008, 30 infertile patients underwent THLPA. The dye-test, hys…

OBJECTIVE: To investigate the metabolism of lipid, calcium and phosphorus in women with endometriosis. METHODS: Clinical data of 223 patients with endometriosis and 200 patients without endometriosis were retrospectively analyzed. Electroc…

OBJECTIVE: To investigate the changes in histological characteristics and collagen content in uterosacral and cardinal ligaments of perimenopausal women in relation to relaxation of pelvic supports. METHODS: Twenty-eight subjects undergoin…

OBJECTIVE: To set up the proteomic protein profiling of adenomyotic tissue and normal uterine muscle and identify the abnormally expressed proteins in adenomyotic tissue. METHODS: Samples of adenomyotic tissue (adenomyosis group) and age-m…

OBJECTIVE: To investigate the expression of claudin-4 in the eutopic and ectopic endometrium of women with endometriosis and evaluate the role of claudin-4 in the pathogenesis of endometriosis. METHODS: Thirty-five women with endometriosis…

OBJECTIVE: To investigate expression of elastin, lysyl oxidase (LOX) and elafin in cardinal ligament of women with pelvic organ prolapse (POP) so as to determine their contributions to POP. METHODS: The cardinal ligament samples were obtai…

OBJECTIVE: To study the inhibitory effect on the expression of regulated upon activation, normal T cell expressed and secreted (RANTES) and monocyte chemotactic activity of ectopic endometrial stromal cells by nuclear factor (NF)-kappaB dec…

OBJECTIVE: To study intermediate and long term efficacy of uterine arterial embolization (UAE) with sodium alginate microspheres (KMG) at diameters 500-00 microm in treatment of diffuse adenomyosis. METHODS: Totally 40 patients with standa…

OBJECTIVE: To explore the secretion of chemokine regulated upon activation normal T cell expressed and secreted (RANTES) influenced by the complex microenvironment in the peritoneal cavity of women with endometriosis and investigate chemota…

OBJECTIVE: To analyze the relevance between the effect on dysmenorrhea of uterine artery embolization (UAE) in treatment of adenomyosis (AM) in different periods of the menstrual cycle and the time of the operation. METHODS: Totally 225 ca…

OBJECTIVE: To evaluate the value of human epididymis secretory protein 4 (HE4) and CA(125) in the diagnosis of ovarian malignancy. METHODS: HE4 and CA(125) in the serum specimens of malignant ovarian tumor group (30 cases), benign ovarian …