The authors presented the importance of the gynecological laparoscopy for diagnosis of the external genital endometriosis in its different forms. In the last 20 years, it was seen that laparoscopy is not only the basic method for diagnostic…
Aromatase P-450 is a key enzyme in the production of estrogens, that is, the conversion of androstenedione and testosterone to estrone and estradiol. Aromatase is a good target for selective inhibition. New aromatase inhibitors provide a go…
The purpose of this study was to describe the endothelial cell activity of the endometrial tissue in women with and without endometriosis, and find out the diagnostic opportunities for everyday gynecologic practice. There were 30 women with…
There were checked out 32 women in concern with genital bleeding receiving Tamoxifen 20 mg daily for a period of an year. The above mentioned were receiving this medicine because of breast cancer with the help of flexible office hysteroscop…
This article reveals one of the newest theories on the pathogenesis of endometriosis. The research was carried out in the last two years and the suggested conclusions give much more convenient explanations on the way endometriosis develops.
A very rare--casuistic--case of endometriosis is presented, which appeared ten years after surgical menopause (hysterectomy and ovariectomy) without concomitant use of hormone replacement therapy or phytoestrogens. The possibilities of endo…
The authors are investigated the frequency of the cases of genital endometriosis, its most frequent localization and the choice of treatment on 864 women patients who have undergone operations connected with other gynaecological disorders a…
OBJECTIVE: To determinate the effectiveness of treatment with gonadotrophine releasing hormone agonist. METHODS: We investigated 164 patients with laparoscopy divided in two groups. Women in first group received Dipherelin 3. 75 mg /lpsen/…
In this study, the authors tried to figure out the value of immunodiagnostics, and especially the protein characteristics of the peritoneal fluid in women with endometriosis. The main purpose was to establish whether this kind of diagnostic…
The aim of our research work was to evaluate the neovascularisation in endometrial cancer and hyperplasia of the endometrium using "power" angio-Doppler technique. Two hundred and fifty patients /200 bulgarian and 50 patients from Greece/ w…
Utrogestan is a modern progesterone, which shows maximal effectiveness with minimal side effects. It is a natural progesterone in micronized form, which makes it suitable for oral administration and vaginal application with same effectivene…
The authors present outcomes of inspection of 300 women suffering from genital endometriosis. Localization and thermocoagulation of endometriosis was performed by diagnostic and operative laparoscopy. After operation women were treated with…
Within the last years, there have been reports on the use of GnRH antagonists, as opposed to agonists, in the treatment of the patients with infertility, uterine fibroids, endometriosis and precocious puberty. The advantage of the antagonis…