Cancer immunology research

Cancer Immunol Res · ISSN (e) 2326-6074 · 3 papers in corpus
2022
doi:10.1158/2326-6066.cir-22-0295 ·PMID:36255418

Fragility of regulatory T (Treg) cells manifested by the loss of neuropilin-1 (NRP1) and expression of IFNγ undermines the immune suppressive functions of Treg cells and contributes to the success of immune therapies against cancers. Intrat…

other 2022
doi:10.1158/2326-6066.CIR-22-0407 ·PMID:36095166

Some patients with advanced clear-cell ovarian cancer (CCOC) respond to immunotherapy; however, little is known about the tumor microenvironment (TME) of this relatively rare disease. Here, we describe a comprehensive quantitative and topog…

2018
doi:10.1158/2326-6066.cir-17-0343 ·PMID:29622581

Triple-negative breast cancer (TNBC) is a leading cause of breast cancer death and is often associated with BRCA1 and BRCA2 mutation. Due to the lack of validated target molecules, no targeted therapy for TNBC is approved. Tissue factor (TF…