PLOS digital health

This scoping review aims to identify the necessary and practical considerations for the design, conduct and safety of decentralized clinical trials (DCTs) that test digital therapeutics (DTx) or software as a medical device (SaMD). The revi…

The differential progression of ten chronic overlapping pain conditions (COPC) and four comorbid mental disorders across demographic groups have rarely been reported in the literature. To fill in this gap, we conducted retrospective cohort …

BackgroundDespite significant advancements in biomedical named entity recognition methods, the clinical application of these systems continues to face many challenges: (1) most of the methods are trained on a limited set of clinical entitie…