Clinical Obstetrics and Gynecology

RU-486, the first clinically available antiprogestin, has numerous gynecologic applications beyond first-trimester pregnancy termination. Long-term administration of 2 mg/day of RU-486 suppresses ovulation while maintaining serum estrogen l…

Many otherwise healthy women will experience a significant disruption in lifestyle from abnormal uterine bleeding. Most of those seeking medical attention will not be at risk for developing anemia. In each case, a thorough search for underl…

Today, evaluating women with abnormal uterine bleeding generally is initiated in the office with an endometrial biopsy. The indications and contraindications for endometrial sampling along with situations which do not, per se, demand sampli…

A review of the clinical features, diagnosis and management of primary and secondary dysmenorrhea updates some old views. Dysmenorrhea is painful menstruation, either cramps with no visible cause, primary dysmenorrhea, or secondary to speci…

1Saint Barnabas Medical Center Livingston, New Jersey 2The University of California—San Diego School of Medicine San Diego, California

Experience with multidisciplinary management of CPP has demonstrated the importance of ruling out and of treating nongynecologic conditions such as myofascial syndrome, irritable bowel syndrome, urethral syndrome, and psychogenic pain in wo…

Recent investigations have documented the importance of ruling out occult nongynecologic diagnoses such as myofascial syndrome, IBS, urethral syndrome, and psychogenic disorders in women with CPP and normal laparoscopy. In light of current …

The development of GnRH agonists has had a major impact on the practice of gynecology and reproductive endocrinology. The clinical usefulness of GnRH agonists will increase as modes of administration are improved and indications become bett…

University of Arkansas Little Rock, Arkansas University of Cincinnati College of Medicine Cincinnati, Ohio

Danazol-induced Pseudomenopause in the Management of Endometriosis W Paul Dmowski; Clinical Obstetrics and Gynecology

In conclusion, different models of physician-patient interactions will be effective at certain times in any long-term relationship between a physician and a patient with chronic disease. Even the most involved patient under certain conditio…

The risk for developing endometriosis begins at puberty and extends to menopause in women of all races. The major pathway in the pathogenesis of this disease is the transplantation of endometrial cells to the pelvis and other abdominal orga…

In summary, endometriosis is a protean pathologic entity of uncertain nature and etiology, occurring commonly in the pelvis and rarely in remote sites. The lesions are characterized by gross and microscopic evidence of endometrium, past and…

Houston, Diana E. PhD; Noller, Kenneth L. MD; Melton, L Joseph III MD; Selwyn, Beatrice J. ScD Author Information