Menopause (New York, N.Y.)

OBJECTIVES: To analyze the association between primary infertility and infertility type with the age of natural menopause. METHODS: This is a retrospective cohort study reviewing a subset of women from the Mayo Primary Infertility Cohort (…

OBJECTIVES: To challenge the perception that endometriosis uniformly regresses after menopause by presenting the case of repeated, pathology-confirmed symptomatic recurrences spanning two decades after menopause, and to emphasize key consid…

OBJECTIVES: To determine the risk of developing de novo carpal tunnel syndrome (CTS), arthritis, or rheumatoid arthritis in women who underwent hysterectomy with bilateral ovarian conservation (H-OC) before reaching spontaneous menopause. …

ObjectivesTo quantify the burden of sleep disturbances on health-related quality of life (HRQoL) and mental well-being in perimenopausal and postmenopausal women with/without co-occurring vasomotor symptoms (VMS).MethodsPerimenopausal and p…

ObjectiveReproductive history may help identify women at higher risk for experiencing menopausal symptoms. We hypothesized that gestation length and offspring birthweight for gestational age z-scores would be associated with menopausal symp…

OBJECTIVE: The primary objective of this study was to determine whether women with and without a history of endometriosis experience menopause differently, in terms of their satisfaction with quality of life. METHODS: This study was conduc…

ObjectivesTo summarize the literature on the rediscovery and clinical exploration of the fourth natural estrogen estetrol (E4), more than 100 years after the discovery of estrone (E1), estradiol (E2), and estriol (E3).MethodsLiterature revi…

AbstractMenopause, defined by the cessation of menstrual cycles after 12 months of amenorrhea not due to other causes, is associated with significant hormonal changes, primarily a decrease in estrogen, androgen, and progesterone levels. Thi…

OBJECTIVES: To better understand whether history of infertility is associated with anti-Müllerian hormone (AMH) levels later in life, outside of reproduction. METHODS: Among 1,758 premenopausal women in the Nurses' Health Study II with mea…

IMPORTANCE AND OBJECTIVE: Postmenopausal endometriosis is a complex condition that challenges the conventional belief that endometriosis resolves with menopause. Despite the cessation of menstruation, a subset of women continues to experien…

ObjectiveWe examined the long-term effects of premenopausal bilateral oophorectomy (PBO) with or without concurrent or preceding hysterectomy on physical and cognitive function and on odds of chronic conditions.MethodsWe enrolled 274 women …

ObjectiveThis study aimed to explore the risk factors for intrauterine device (IUD) embedment in postmenopausal women.MethodsA total of 731 women who underwent hysteroscopy for IUD removal from January 2019 to December 2021 were included in…

ObjectiveTo identify the optimal triage procedure for endometrial biopsies in postmenopausal women.MethodsThe clinical information of 470 postmenopausal women with endometrial biopsy results and postmenopausal bleeding (PMB) and/or transvag…

ObjectiveExpanding access to legal cannabis has dovetailed with increased interest in medical cannabis (MC) use; however, there is a paucity of research examining MC use to alleviate menopause-related symptoms. This survey study assessed pa…

OBJECTIVES: Evaluate the proportion of justified bilateral salpingo-oophorectomy (BSO) at hysterectomy, based on pathologic diagnosis, and determine prevalence of avoidable BSO based on pre- and intraoperative considerations and pathologic …

ObjectiveThe incidence of postmenopausal endometrial cancer (EC) is rising, and the uterine microbiota has recently been suggested to be an etiology of EC. However, the differences in microbiota profiles in paired EC and the adjacent non-EC…

ObjectiveTo understand prevalence, severity, impact, and treatment of vasomotor symptoms associated with menopause, using cross-sectional survey data.MethodsThis online, two-part survey was conducted in East Asia among women 40-65 years rec…

ObjectiveTo determine prevalence and health-related quality of life (HRQOL) of moderate-to-severe vasomotor symptoms (VMS) in postmenopausal women in Europe, the US, and Japan, and among subgroups of women not taking hormone therapy (HT).Me…

ObjectiveThe incidence of carpal tunnel syndrome (CTS) is higher in women, and peaks around the age of menopause. Therefore, we investigated whether bilateral oophorectomy is associated with an increased risk of severe CTS.MethodsWe include…

OBJECTIVE: To study bone mineral density (BMD) in women with and without pelvic deep infiltrating endometriosis (DIE) who underwent early bilateral oophorectomy (BO). METHODS: A case-control study was performed in 83 women who underwent ear…

OBJECTIVE: To evaluate predictors of bilateral salpingo-oophorectomy at hysterectomy and determine rate of unnecessary bilateral salpingo-oophorectomy. METHODS: Retrospective review of hysterectomies at six Ontario, Canada hospitals from Ju…

Uterine fibroids (UFs) are benign tumors that arise from a single genetically altered mesenchymal stem cell under the influence of gonadal hormones. UFs are the most common benign gynecologic tumors in premenopausal women worldwide. It is e…

ObjectiveWe studied eight mental health conditions diagnosed before bilateral oophorectomy performed for nonmalignant indications.MethodsWe identified 1,653 premenopausal women who underwent bilateral oophorectomy for a nonmalignant indicat…

ObjectiveThis meta-analysis aims to investigate serum androgen profiles (testosterone, dehydroepiandrosterone sulfate, androstenedione, and sex hormone-binding globulin) in women with premature ovarian failure and to establish if there is e…