IntroductionPeak alpha frequency (PAF), an electroencephalography measure, has gained interest due to its association to pain-related neural processes in both healthy and clinical populations. In healthy groups, PAF derived from the sensori…
Living with chronic pain presents significant challenges and disruptions, thus motivating the use of coping strategies to manage pain and its impact in everyday life. Yet how individuals cope with chronic pain and why some people show bette…
INTRODUCTION: Evidence increasingly shows small nerve fibre pathology in subsets of people with fibromyalgia through skin biopsy, corneal confocal microscopy, and microneurography. However, blood-based biomarkers of ongoing neuronal damage,…
IntroductionBack pain (BP) is a complex heritable trait with an estimated heritability of 40% to 60%. Less than half of this can be explained by known genetic variants identified in genome-wide association studies.ObjectivesWe applied a pow…
Clinical disorders associated with chronic pelvic pain (CPP) cause demonstrable emotional and physical dysfunction as well as increased health care utilization. Interventions that have been studied for the treatment of CPP often provide ina…
IntroductionChronic ocular pain (COP) is a widespread pain condition that presents clinical challenges, has heterologous and overlapping etiologies across patients, and can have a debilitating effect on quality of life. It can manifest with…
IntroductionNot only is chronic pain more prevalent in women but also the intersection between chronic pain and reproductive health adds complexity in pain management strategies and care plan development. Despite this, it remains unclear wh…
Bridging the gender pain gap requires collaborative efforts that address female-specific biological and psychosocial dimensions of pain through evidence-based, compassionate and empathy-driven approaches.
IntroductionNo prediction models exist for the success for buprenorphine initiation in opioid-naïve patients or in transition from other opioids in patients treated for chronic pain.ObjectivesTo create a prediction model for the successful …
IntroductionNeuropathic pain (NP) is one of the most devastating and under-managed symptoms of multiple sclerosis (MS). As it stands, NP is a difficult condition to treat, as many commonly used pain therapies are ineffective. Research has n…
Animal studies have shown androgens, especially testosterone, may have an analgesic effect on nociceptive behavior. However, it is unclear if this effect is present in humans. This review and meta-analysis aim to summarize and synthesize th…
IntroductionThe Menstrual Sensitivity Index (MSI), assessing the attunement to and fear of menstrual symptoms, was recently developed and validated in an adult sample.ObjectivesThe objective of this study was to validate the MSI in adolesce…
Introduction and objectivesLipedema is a widespread severe chronic disease affecting mostly women. Characterized by painful bilateral fat accumulation in extremities sparing hands and feet, objective measurement-based diagnosis is currently…
Dysregulation of sleep heightens pain sensitivity and may contribute to pain chronification. Interventions which consolidate and lengthen sleep have the potential to improve pain control. The main objective of this systematic review was to …
The endocannabinoid system (ECS) is an essential endogenous signaling system that may be involved in the pathophysiology of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS). Further research is required to understand the role o…
IntroductionThere is a need to identify objective cortical electrophysiological correlates for pain relief that could potentially contribute to a better pain management. However, the field of developing brain biomarkers for pain relief is s…
Chronic pelvic pain (CPP) is a highly prevalent condition which is underdiagnosed and poorly understood. The purpose of this review is to outline the various aspects of the nature of CPP, including its etiologies, clinical presentation, and…
IntroductionCritical for the diagnosis and treatment of chronic pain is the anatomical distribution of pain. Several body maps allow patients to indicate pain areas on paper; however, each has its limitations.ObjectivesTo provide a comprehe…
ObjectiveDetermine if chronic low back pain (LBP) is associated with DNA methylation signatures in human T cells that will reveal novel mechanisms and potential therapeutic targets and explore the feasibility of epigenetic diagnostic marker…
It is my pleasure to inform you that the 22nd International Pelvic Pain Society (IPPS) Annual Scientific Meeting on Pelvic Pain was a success. The 2019 program provided participants with an expanded understanding of chronic pelvic pain eval…