Alzheimer's research & therapy

· 3 papers in corpus
2026
doi:10.1186/s13195-026-02066-9 ·PMID:42050742

BackgroundFew studies comprehensively examined women's life-course reproductive patterns and the risk of dementia. This study aims to examine the association between women's reproductive life sequence and dementia, and to explore the potent…

2025
doi:10.1186/s13195-025-01834-3 ·PMID:40796907

BackgroundAlzheimer's disease (AD) is characterized by cognitive decline, amyloid-beta (Aβ) accumulation, and tau hyperphosphorylation. Effective therapies remain limited; therefore, recent studies have explored microRNAs as potential thera…

2020
doi:10.1186/s13195-020-00662-x ·PMID:32807237

BackgroundTreatments are needed to address the growing prevalence of Alzheimer's disease (AD). Clinical trials have failed to produce any AD drugs for Food and Drug Administration (FDA) approval since 2003, and the pharmaceutical developmen…