BACKGROUND AND OBJECTIVES: Calcitonin gene-related peptide (CGRP) plays a central mechanistic role in migraine and is an established drug target. However, it remains unclear whether peripheral plasma CGRP levels meaningfully reflect disease…
BACKGROUND AND OBJECTIVES: Previous studies, including large cohort analyses comparing vaccinated and unvaccinated adults, suggest that routine immunizations such as inactivated influenza vaccines (IIVs) may reduce Alzheimer dementia (AD) r…
BACKGROUND AND OBJECTIVE: To describe the relative frequency, demographics, comorbidities, and health care utilization of veterans who receive migraine care at the Veteran's Health Administration (VHA) and to evaluate differences by gender.…
BACKGROUND AND OBJECTIVES: Most studies of health-related quality of life (HRQoL) in multiple sclerosis (MS) have been cross-sectional. The few longitudinal studies have not accounted for potential heterogeneity in HRQOL trajectories. There…
To assess myofascial dysfunction and sensitization beyond the pelvis in women with endometriosis-associated chronic pelvic pain (endo-CPP).
OBJECTIVE: Our aim was to evaluate seizure course in catamenial epilepsy (CE) and noncatamenial epilepsy (NCE) during pregnancy. METHODS: We prospectively followed women referred to our Epilepsy Center for pregnancy planning to the end of …
Some ovarian steroids such as estradiol (E)1,2 and progesterone (P)3,4 have neuroactive properties that can affect neuronal excitability. Cyclic changes in the serum concentrations of these steroids in relation to the menstrual cycle may in…
Found in inflammatory zone (FIZZ) 2, also known as resistin-like molecule (RELM)-β, belongs to a novel cysteine-rich secreted protein family named FIZZ/RELM. Its function is unclear, but a closely related family member, FIZZ1, has profibrot…
A woman with a long history of menstruation-related headaches, at times associated with papilledema and brief episodes of unresponsiveness, was experiencing recurrent cryptogenic subarachnoid hemorrhage. Although the source of hemorrhage wa…
We present the second reported patient with cerebral endometriosis. She had repetitive partial seizures on the first day of her menstrual cycle. The seizures were controlled by danazol after the causative lesions were surgically removed.
Sciatic endometriosis may cause cyclic sciatic pain and a sensorimotor mononeuropathy. Neurophysiologic tests and conventional radiologic examinations are of little value in delineating this lesion, but the pelvic CT appearance of sciatic e…